Results 81 to 90 of about 977,904 (291)

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

Starfish Optimization-Based Fractional Order 3DoF Control Strategy for Enhanced Frequency Stability in RES-Based Microgrids

IEEE Access
Frequency stability in microgrids presents vital challenges owing to unpredictable load variations and intermittent Renewable Energy Sources (RESs). This study investigates enhanced Load Frequency Control methodologies to address stability challenges ...
Imran Khan, Suheel Abdullah Malik, Amil Daraz, Muhammad Majid Gulzar, Baitullah Bareer   +4 more
doaj   +1 more source

A Partial Derivative Approach to the Change of Scale Formula for the Function Space Integral

, 2020
We investigate the partial derivative approach to the change of scale formula for the functon space integral and we investigate the vector calculus approach to the directional derivative on the function space and prove relationships among the Wiener ...
Young Sik Kim
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Performance Analyses of Four-Instant Discretization Formulas With Application to Generalized-Sylvester-Type Future Matrix Equation

IEEE Access, 2019
For solving generalized-Sylvester-type future matrix equation (GS-type FME) effectively, the continuous zeroing neural network (ZNN) model should be discretized by appropriate discretization formula.
Zhangqiang Yin, Kang Liu, Yuanhang Chen, Rui Xue, Jian Li, Yang Shi   +5 more
doaj   +1 more source

A Simple Derivation of Josephson's Formulae in Superconductivity

Letters in Mathematical Physics, 2000
A simple and general derivation of Josephson formulae for the tunneling currents is presented on the basis of Sewell's general formulation of superconductivity in use of off-diagonal long range order (ODLRO).
openaire   +3 more sources

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Existence and Stability for Fractional Differential Equations with a ψ–Hilfer Fractional Derivative in the Caputo Sense

Mathematics
This article aims to explore the existence and stability of solutions to differential equations involving a ψ-Hilfer fractional derivative in the Caputo sense, which, compared to classical ψ-Hilfer fractional derivatives (in the Riemann–Liouville sense),
Wenchang He, Yuhang Jin, Luyao Wang, Ning Cai, Jia Mu   +4 more
doaj   +1 more source

Analogues of Jacobi’s derivative formula II

The Ramanujan Journal, 2016
In this paper, we realize high-level versions of Jacobi's derivative formula to all the rational characteristics corresponding to level $k \,\,(k=3,4,5,6).$ For this purpose, we propose the method to obtain derivative formulas by means of the residue theorem.
openaire   +2 more sources

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source