Results 71 to 80 of about 977,904 (291)

Advancing Fractional Riesz Derivatives through Dunkl Operators

Mathematics, 2023
The aim of this work is to introduce a novel concept, Riesz–Dunkl fractional derivatives, within the context of Dunkl-type operators. A particularly noteworthy revelation is that when a specific parameter κ equals zero, the Riesz–Dunkl fractional ...
Fethi Bouzeffour
doaj   +1 more source

Derivative of the expected supremum of fractional Brownian motion at [Formula: see text]

, 2022
The H-derivative of the expected supremum of fractional Brownian motion [Formula: see text] with drift [Formula: see text] over time interval [0, T] [Formula: see text] at [Formula: see text] is found.
Rolski, T., Rolski, Tomasz, Dȩbicki, K., Bisewski, K., Bisewski, Krzysztof, Dȩbicki, Krzysztof   +5 more
core   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source

Analysis of Quantum Multiplicative Calculus and Related Inequalities

Mathematics
This article investigates the exact meaning of a quantum derivative result and the corresponding definition of a quantum definite integral in multiplicative calculus from a geometrical viewpoint.
Muhammad Nasim Aftab, Saad Ihsan Butt, Mohammed Alammar, Youngsoo Seol   +3 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Blood Balance Advanced Formula Hoax | Blood Balance Advanced Formula Reviews

, 2021
Blood Balance Advanced Formula Hoax- At present, you can easily buy these Blood Balance Advanced Formula Support supplements online. If you want you can always consult a health expert to know more details.
Advanced Formula
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Existence and Attractivity of Mild Solutions for Fractional Diffusion Equations Involving the Regularized ψ-Hilfer Fractional Derivatives

Axioms
The regularized ψ-Hilfer derivative within the sense of Caputo is an improved version of the ψ-Hilfer fractional derivative, primarily because it addresses the issue where the initial conditions of problems involving the ψ-Hilfer fractional derivative ...
Luyao Wang, Yuhang Jin, Wenchang He, Jia Mu   +3 more
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source