ABSTRACT Phytocannabinoids are bioactive metabolites derived from the Cannabis sativa plant. They have garnered attention due to their recreational uses and therapeutic potential. Although various analytical strategies have been employed for their analysis, mass spectrometry (MS) coupled to chromatographic separation is superior due to its sensitivity ...
Radwa Mahmoud +2 more
wiley +1 more source
Absolute Quantitation of Phosphopeptides and Glycopeptides Using Coulometric Mass Spectrometry. [PDF]
Tanim-Al Hassan M +7 more
europepmc +1 more source
ABSTRACT The review examines the evolution of chemical ionization mass spectrometry (CI‐MS), a technique developed in 1966 by Field and Munson. CI is a soft‐ionization method that produces more intense molecular ions with less fragmentation than electron ionization (EI).
Malvika Dutt +4 more
wiley +1 more source
Arg-C Ultra Simplifies Histone Preparation for LC-MS/MS. [PDF]
Ryzhaya P +3 more
europepmc +1 more source
Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik +3 more
wiley +1 more source
Efficient Stereochemical Analysis of Hydroxy Fatty Acids Using PGME and PAME Derivatization. [PDF]
Um S, Lee J, Kim SH.
europepmc +1 more source
Residual Chemical Shift Anisotropies in the Structure Determination of Small Molecules
Plasma neutrophil elastase(ELANE) was markedly elevated in patients with alcohol use disorder, indicating a dysregulated protease‐antiprotease inflammatory balance characterised by decreased SERPINA3. ELANE showed excellent diagnostic specificity(AUC = 0.8683), supporting its potential utility as a neuroinflammatory biomarker for AUD.
Nilamoni Nath +3 more
wiley +1 more source
Sensitive Profiling of Human Milk Oligosaccharides in Human Colostrum and Breast Milk by Capillary Electrophoresis-Mass Spectrometry. [PDF]
Smolkova D +4 more
europepmc +1 more source
A Rapid and Sensitive Method for the Determination of Chitosan Concentration by NMR Relaxometry
ABSTRACT A rapid, reagent‐free method for the quantification of chitosan in aqueous solutions was developed using 1H nuclear magnetic resonance (NMR) relaxometry. Transverse relaxation times (T2) of chitosan solutions (5–1000 mg/L) were measured with a Carr–Purcell–Meiboom–Gill (CPMG) sequence on a benchtop NMR relaxometer.
Marta Férová, Jiří Kalina
wiley +1 more source
Unveiling the Accurate Site-Specific <i>N</i>- and <i>O</i>-Glycosylation of Hyperglycosylated Erythropoietin Drugs by an Integrated Approach. [PDF]
Wu S +11 more
europepmc +1 more source

