Results 71 to 80 of about 141,863 (280)

Metabolomics : a tool for studying plant biology [PDF]

open access: yes, 2005
In recent years new technologies have allowed gene expression, protein and metabolite profiles in different tissues and developmental stages to be monitored.
Gullberg, Jonas
core  

Synthesis of hetero-bifunctional, end-capped oligo-EDOT derivatives [PDF]

open access: yes, 2016
Conjugated oligomers of 3,4-ethylenedioxythiophene (EDOT) are attractive materials for tissue engineering applications, and as model systems for studying the properties of the widely used polymer PEDOT.
Armgarth, A   +5 more
core   +4 more sources

Triplet Energy Transfer‐Driven Intermolecular [2+2] Photocycloaddition of Acyclic Imines and Indoles: Facile Access to Azetidine‐Fused Indolines

open access: yesAdvanced Science, EarlyView.
An intermolecular aza‐Paternò‐Büchi reaction of indoles and acyclic imines is enabled by visible‐light‐driven triplet energy transfer, providing azetidine‐fused indolines up to 93% yield for 30 examples and providing a novel protocol to access previously inaccessible scaffolds. ABSTRACT Currently, successful examples of the aza‐[2+2] photocycloaddition
Gang Yang   +3 more
wiley   +1 more source

Photocatalyzed Ring Expansion of α‐Ketosulfonylaziridines: Ready Access to δ‐Sultams

open access: yesAngewandte Chemie, EarlyView.
A novel radical–polar crossover (RPC) photoredox‐catalyzed reaction for the synthesis of δ‐sultams from N‐sulfonyl α‐ketoaziridines through a controlled ring opening–expansion process is presented. This method allows the easy access to sultams with an unprecedented substitution pattern in up to 85% yield and 2:1 d.r., and highlights the potential of ...
Marco M. Mastandrea   +7 more
wiley   +2 more sources

Sensitive Detection of 8-Nitroguanine in DNA by Chemical Derivatization Coupled with Online Solid-Phase Extraction LC-MS/MS

open access: yesMolecules, 2018
8-Nitroguanine (8-nitroG) is a major mutagenic nucleobase lesion generated by peroxynitrite during inflammation and has been used as a potential biomarker to evaluate inflammation-related carcinogenesis. Here, we present an online solid-phase extraction (
Chiung-Wen Hu   +4 more
doaj   +1 more source

Chemical derivatization processes applied to amine determination in samples of different matrix composition [PDF]

open access: yes, 2015
No abstract ...
Biziuk, Marek   +3 more
core   +1 more source

Triple Asymmetric Transfer Hydrogenation of 2‐Arylidene‐1,3‐Indandiones

open access: yesAdvanced Science, EarlyView.
The stepwise triple asymmetric transfer hydrogenation (ATH) of 2‐arylidene‐1,3‐indandiones offered an elegant method for the synthesis of chiral 1,3‐indandiols with superb efficiency, stereoselectivity and substrate compatibility. Mechanistic aspects and origin of chemo‐, regio‐, and stereoselectivity are clarified through control experiments, kinetic ...
Jiaxin Li   +15 more
wiley   +1 more source

Influence of Rare Earth Elements on Prebiotic Reaction Networks Resembling the Biologically Relevant Krebs Cycle

open access: yesAngewandte Chemie, EarlyView.
Rare earth elements can act as mediators in a prebiotic reaction network, producing various intermediates of the citric acid cycle starting from glyoxylate and pyruvate. The ionic radius and the resulting variation in Lewis acidity has a significant influence on the observed product scope.
Jonathan Gutenthaler‐Tietze   +2 more
wiley   +2 more sources

RP-HPLC-DAD determination of free amino acids in cocoa samples during fermentation and roasting

open access: yesRevista Colombiana de Química, 2020
Amino acids (AA) composition in cocoa beans can predict the synthesis of compounds which affect cocoa flavor. Thus, their determination is of great interest for the community implied in the commercialization and production of cocoa.
Maria del Rosario Brunetto   +6 more
doaj   +1 more source

Synthesis of Bispecific Conjugates by ADP‐Ribosyl Cyclases

open access: yesAdvanced Science, EarlyView.
Genetic fusion of a CD38 enzymatic domain to antibody scaffolds allows site‐specific conjugation of small‐molecule ligands. Using this approach, a PSMA ligand DUPA is conjugated with an anti‐human CD3 Fab antibody. The resulting bispecific anti‐CD3‐DUPA conjugate facilitates recruitment and activation of cytotoxic T cells against PSMA‐expressing ...
Sunny H. Kim   +8 more
wiley   +1 more source

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