Results 131 to 140 of about 1,910,776 (311)

Challenges, Unmet Needs, and Future Directions for Nanocrystals in Dermal Drug Delivery

Molecules
Nanocrystals, defined as crystalline particles with dimensions in the nanometer range (
Muzn Alkhaldi, Cornelia M. Keck
doaj   +1 more source

3D‐Printed Corneal Substitutes: Materials, Fabrication, and Preclinical Progress

Advanced Materials Technologies, EarlyView.
Successful clinical translation of 3D‐printed corneal substitutes relies on the interplay between the bioink properties, cellular component, and the fabrication process. These factors influence the critical properties of the construct, including optical transparency, mechanical stability, suture retention, that ultimately govern long‐term stromal ...
Shadi Moshayedi, Ashley Vazquez, Alexander J. Choi, Dimitrios Karamichos, Jayoung Kim   +4 more
wiley   +1 more source

FLAME RETARDANT TEXTILE FINISHING: IN VITRO ASSESSMENT OF DERMAL ABSORPTION [PDF]

, 2019
Flame Retardants (FR) are a group of anthropogenic environmental contaminants used in textile finishings. Currently, the largest marked group of FRs is brominated FR considered toxic, persistent and bioaccumulative.
Martí, Meritxell, Alonso, Cristina, Coderch Negra, M. Luisa, Manich, Albert M.   +3 more
core  

Deep‐Tissue Light Generation via Whispering Gallery Mode Lasing From a Commercial Nylon Fiber for Biomedical Applications

Advanced Materials Technologies, EarlyView.
A dyed nylon fiber is implemented inside the scattering phantom and skin tissue. The deep‐tissue light generation via whispering gallery mode lasing is demonstrated, achieving a depth of >50 times transport mean free path in scattering phantom and 3 mm beneath skin.
Dongqin Ni, Florian Klämpfl, Fernando Lahoz, Michael Schmidt, Martin Hohmann   +4 more
wiley   +1 more source

Proposal for revision of default dermal absorption values in regulatory toxicology [PDF]

The BfR compiled an updated dataset of dermal absorption in vitro studies for pesticides - the BfR dataset 2024. BfR developed an R script to efficiently compile and standardize data from multiple template files to generate a consolidated, standalone ...
Marx-Stoelting, Philip, Städele, Veronika, Martin, Sabine, Wend, Korinna   +3 more
core  

Development and ex vivo / in vitro evaluation of sodium alginate/ hydroxypropyl methylcellulose films for dermal and/or transdermal delivery of p-hydroxycinnamic acid

Journal of Holistic Integrative Pharmacy
Objective: Skin diseases and chronic wounds are health problems that require solutions for health systems due to their high costs and difficulties in effective and rapid treatment.
Ayşe Pınar Yağcılar, Gökçe Karaotmarlı Güven, Emre Şefik Çağlar, Neslihan Üstündağ Okur, Panoraia I. Siafaka   +4 more
doaj   +1 more source

GPR124 Alleviates Blood–Brain Barrier Disruption by Enhancing Microvascular Endothelial Function after Traumatic Brain Injury

Advanced Science, EarlyView.
Our study reveals the protective role of GPR124 in maintaining BBB integrity and promoting neurological recovery following TBI. It makes a significant contribution by uncovering a novel molecular interaction between GPR124 and FGFBP1 and linking this to activation of the Wnt/β‐catenin signaling pathway in vascular repair mechanisms.
Chen Wang, Lin Cai, Qiuyuan Gong, Yang Yang, Yuqing Liang, Xinyu Niu, Lai Wei, Ze Liu, Shengju Wu, Yinghui Men, Yaohui Tang, Jun Ding, Hengli Tian, Hao Chen   +13 more
wiley   +1 more source

Systemic and immunotoxicity induced by topical application of perfluoroheptane sulfonic acid (PFHpS) or perfluorooctane sulfonic acid (PFOS) in a murine model

Journal of Immunotoxicology
Per- and polyfluoroalkyl substances (PFAS) are a large group of synthetic surfactants of over 12,000 compounds that are incorporated into numerous products for their chemical and physical properties.
Lisa M. Weatherly, Hillary L. Shane, Laurel G. Jackson, Ewa Lukomska, Rachel Baur, Madison P. Cooper, Stacey E. Anderson   +6 more
doaj   +1 more source

A Pentaradial and Bilateral Combined Photoreception System in the Sea Cucumber is Mediated by a Blue Light‐Sensitive R‐Opsin

Advanced Science, EarlyView.
The sea cucumber Holothuria leucospilota detects blue and adjacent wavelengths of light via an r‐opsin with a maximum absorption at 459 nm. In the oral tentacles, papillae, and tube feet, distinct light‐sensing structures with specialized morphologies are formed, constituting a unique pentaradial and bilateral combined photoreception system.
Jiasheng Huang, Chunhua Ren, Zhou Qin, Yimeng Cui, Bingbing Zhang, Peng Luo, Xuan Wang, Yaoqi Xie, Xin Zhang, Aifen Yan, Yang Zhang, Dingding Fan, Yang Liu, Wenjie Pan, Xiao Jiang, Lihong Yuan, Haipeng Qin, David M. Irwin, Chaoqun Hu, Yang Liu, Ting Chen   +20 more
wiley   +1 more source

Redox‐Dependent Chaperoning of GBF1 Condensates Regulates Seed Germination in Arabidopsis

Advanced Science, EarlyView.
In dormant seeds (low ROS), GBF1 forms liquid condensates to repress the germination gene CathB3, and the chaperone GIP1 maintains condensate liquidity and repressive activity. Upon imbibition (high ROS), ROS oxidize GIP1 during germination, impairing its chaperone function.
Yunying Wang, Xiaofeng Fang
wiley   +1 more source