Immunotherapy using pullulan-conjugated Der f 2 allergen in canine atopic dermatitis: An anti-inflammatory agent-sparing approach. [PDF]
Background – Allergen immunotherapy is used as aetiological treatment for canine atopic dermatitis (cAD). Objective – To assess the anti‐inflammatory agent‐sparing effect over 1 year of immunotherapy using pullulan‐conjugated recombinant Der f 2 (rDf2‐P). Conclusions and Clinical Relevance – Der f 2‐P immunotherapy can lead to a rapid reduction in anti‐
Nagata M +7 more
europepmc +2 more sources
An open-label pilot study on an adsorbent mousse containing adelmidrol in client-owned cats with feline atopic skin syndrome and associated seborrhoea. [PDF]
Background – Besides pruritus and skin lesions, cats with feline atopic skin syndrome (FASS) may have seborrhoea. Hypothesis/Objectives – The aim of this pilot study was to investigate whether an adsorbent mousse containing tapioca starch, adelmidrol and a nonpharmacological antimicrobial complex could decrease FASS‐associated seborrhoea in cats ...
Noli C +4 more
europepmc +2 more sources
Efficacy and field safety of ilunocitinib for the control of atopic dermatitis in client-owned dogs: A multicentre, double-masked, randomised, placebo-controlled clinical trial. [PDF]
Background – Inhibition of the Janus kinase (JAK) pathway is a well‐established option for canine atopic dermatitis (cAD). Objective – To evaluate the efficacy and safety of ilunocitinib, a novel JAK inhibitor for the control of pruritus and skin lesions in client‐owned dogs with cAD.
Forster S +5 more
europepmc +2 more sources
Transcriptomic profiling of dorsal root ganglia in atopic and healthy dogs: A comparative RNA sequencing study with implications in cutaneous itch research. [PDF]
Background – Itch is a common symptom in skin disorders. While the neural pathways of itch transmission from the skin to the brain are well‐understood in rodents, the same pathways in dogs remain unclear. The knowledge gap hinders the development of effective treatments for canine itch‐related disorders.
Tamamoto-Mochizuki C, Mishra SK.
europepmc +2 more sources
Updated insights into the molecular pathogenesis of canine atopic dermatitis. [PDF]
Abstract Atopic dermatitis (AD) is a common and chronic inflammatory skin disease with frequent relapses. The genomics revolution has greatly contributed and revolutionised our knowledge of human AD; understanding the molecular skin fingerprint of AD and associated pathogenic immune pathways has led to preclinical assessments of several novel ...
Banovic F.
europepmc +2 more sources
Associação entre dermatite atópica e mastocitoma em cães
Foi realizado um estudo para verificar se há associação entre a ocorrência de mastocitoma cutâneo e dermatite atópica em cães atendidos de 2014 à 2018, com a casuística do Hospital Veterinário da Universidade Vila Velha.
Rebeka Ferro Tosta Kalil +1 more
doaj +1 more source
Epidemiological and clinical features of allergic conjunctivitis in a reference center [PDF]
BACKGROUND: To evaluate demographic and clinical features of patients with allergic conjunctivitis in a reference center. METHODS: Prospective study using sings and symptoms graduated by standardized charts for clinical diagnosis.
Belfort, Rubens Junior +3 more
core +3 more sources
Prebiotics, probiotics and symbiotics on prevention and treatment of allergic diseases [PDF]
OBJECTIVE: To review current evidence about the effects of probiotics, prebiotics and symbiotics on the immune development as well as on the prevention of allergic diseases in children.
Cocco, Renata Rodrigues +4 more
core +3 more sources
Psoriasis in childhood and adolescence [PDF]
A psoríase é doença inflamatória crônica, imunologicamente mediada, recorrente e de caráter universal. Aproximadamente um terço dos adultos acometidos refere início da doença antes dos 16 anos de idade.
ARNONE, Marcelo +3 more
core +2 more sources
As perturbações do sono são frequentes em crianças com dermatite atópica, com impacto negativo significativo na sua qualidade de vida e com consequências no seu comportamento e desempenho cognitivo.
Ana Sofia Borges +2 more
doaj +1 more source

