Results 111 to 120 of about 35,454 (303)

Non‐Invasive Scalp Tape‐Strip RNA Sequencing Captures Disease Activity and Treatment‐Response Signatures in Alopecia Areata

Allergy, EarlyView.
Non‐invasive scalp tape‐strip RNA sequencing captures core immune and follicular molecular signatures in alopecia areata. Tape‐strip transcriptomic profiles reflect disease severity and treatment response to baricitinib, with concordance to scalp biopsy‐derived signatures.
Carmen Mochón‐Jiménez, Jesús Gay‐Mimbrera, Viviana Dávila‐Flores, Helen He, Jerry Zhou, Irene Rivera‐Ruiz, Pedro J. Gómez‐Arias, Juan de Luque‐Fernández, Benjamin Ungar, Emma Guttman‐Yassky, Juan Ruano   +10 more
wiley   +1 more source

Occupational airborne contact dermatitis caused by trifluoroacetic acid in an organic chemistry laboratory

, 2019
airborne; allergic contact dermatitis; laboratory workers; occupational; organic chemistry; trifluoroacetic ...
최유원, 최혜영, 변지연
core   +1 more source

Allergic contact dermatitis due to 1,6-hexanediol diacrylate in ostomy patients [Elektronisk resurs]

Background: Many people live with ostomies after life-saving surgery. Ostomy patients often suffer from peristomal dermatitis. Allergic contact dermatitis (ACD) has been reported, mostly due to contact allergy (CA) to topical agents.
Svedman, Cecilia,, Dahlin, Jakob,, Mowitz, Martin,, Hamnerius, Nils,, Lund University., Siemund, Ingrid,   +5 more
core   +1 more source

Early Epidemiologic and Immune Predictors of Atopic Dermatitis: Reduced Cord Blood Regulatory B10 Cells in the Munich Atopy Prediction Study (MAPS)

Allergy, EarlyView.
In this prospective birth cohort from Munich, comprehensive clinical assessments and longitudinal lifestyle questionnaires were combined with cord blood immune profiling. Infants who later developed AD showed altered cord blood immune signatures, including reduced CD4+ T cells, increased B cells and markedly decreased Breg cells. Epidemiologic factors,
S. Preis, S. Kaesler, M. Koeberle, M. Hils, B. Evers, R. L. Silva, Y. Skabytska, L. Schellenberger, H. Hufnagel, M. Schielein, B. Kuschel, Y. Amar, A. Zink, T. Biedermann, Z. Kurgyis   +14 more
wiley   +1 more source

Hypersensitivity to Excipients in Drugs: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT Drugs contain active pharmaceutical ingredients and excipients, compounds which enhance the pharmacokinetics, stability and palatability of the pharmaceutical formulation. While most drug hypersensitivity reactions (DHR) are caused by active ingredients, excipients may also be involved.
Lene H. Garvey, Knut Brockow, Annick Barbaud, Charlotte G. Mortz, Gianfranco Calogiuri, Asli Gelincik, Osman O. Yeğit, Alla Nakonechna, Annette Wagner, Rik Schrijvers, Toon Ieven   +10 more
wiley   +1 more source

High release of hexavalent chromium into artificial sweat in a case of leather shoe–induced contact dermatitis

, 2019
Cases of allergic contact dermatitis due to chromium caused by chromium‐tanned leather articles such as shoes and gloves are well‐known.1, 2 In the European Union, hexavalent chromium in new leather articles on the market is restricted to 3 mg/kg since ...
Mihály Matura, Zheng Wei, Wei, Zheng,, Yolanda S. Hedberg, Matura, Mihaly,, Hedberg, Yolanda,   +5 more
core   +1 more source

Divergent Paths: A Comprehensive Review of Mechanisms and Clinical Implications in Atopic Dermatitis and Psoriasis

Allergy, EarlyView.
ABSTRACT Atopic dermatitis and psoriasis are two common cutaneous chronic inflammatory diseases. Although they share similar immunological mechanisms, their clinical implications in the patient are different. This review compares both diseases from different points of view such as genetics, natural history, triggers of disease, and skin barrier defects
Tali Czarnowicki, Kazunari Sugita, Zenas Yiu, Sandra Díez‐Ribas, Irene Garcia‐Jimenez, Emma Guttman‐Yassky, Luis F. Santamaria‐Babí   +6 more
wiley   +1 more source

Type‐2‐Inflammatory‐Diseases Share Comorbidities, Molecular Signatures, IL4/IL13 Genetics, and Response to IL4/IL13 Blockade

Allergy, EarlyView.
Studies suggest that type 2 inflammatory diseases are driven by overactivation of the IL4/IL13 pathway, manifesting differently in distinct tissues. We performed quantitative analyses using several large independent datasets to explore the interrelation of type 2 inflammatory diseases based on co‐prevalence, genetic predispositions, and transcriptomic ...
Jennifer D. Hamilton, Manuel A. R. Ferreira, Wei Keat Lim, Carlo Sidore, Matthew F. Wipperman, Wenzhen Ge, Xue Song, Changming Xia, Julie E. Horowitz, Andrea T. Hooper, Sara C. Hamon, Jennifer Maloney, Jamie M. Orengo, Zhen Chen, Stephanie Amato Ricci, Bolanle Akinlade, Aris Baras, Gary Herman, Brandy L. Bennett, George D. Yancopoulos   +19 more
wiley   +1 more source

Rapid Human Skin Barrier Disruption by Sodium Dodecyl Sulfate and Associated Molecular Mechanisms

Allergy, EarlyView.
Short‐term exposure to SDS rapidly disrupts human skin barrier integrity within minutes, as detected by real‐time electrical impedance spectroscopy. SDS‐induced barrier dysfunction is driven by oxidative stress, leading to suppression of immune/barrier mediators and activation of stress, lipid remodeling, and epidermal differentiation pathways ...
Manru Li, Huseyn Babayev, Paolo D'Avino, Can Zeyneloğlu, Ceren Bicer, Duygu Yazici, Yagiz Pat, Per Svedenhag, Nicolas Gaudenzio, Cezmi A. Akdis, Yasutaka Mitamura   +10 more
wiley   +1 more source

Allergic Contact Dermatitis in the Hamster

Journal of Investigative Dermatology, 1980
Allergic contact dermatitis to strong, low molecular weight contact allergens can regularly be induced in the hamster. By its clinical course, histopathology and susceptibility to intensification with complete Freund's adjuvant, this hypersensitivity appears congruent with the allergic contact dermatitis observed in other experimental animals and the ...
openaire   +2 more sources