Results 101 to 110 of about 166,203 (279)

When Treatment Meets Natural History: Understanding Early Dermatitis‐Related Adverse Events in Systemic Atopic Dermatitis Trials

JEADV Clinical Practice, EarlyView.
ABSTRACT Biologics and Janus kinase (JAK) inhibitors have transformed the management of atopic dermatitis (AD), yet some patients experience early worsening of disease activity during treatment initiation. In clinical trials, these events are typically recorded as treatment‐emergent adverse events (TEAEs), most commonly coded as “atopic dermatitis”. We
Diego Ruiz Dasilva, Alondra Soto‐Gonzalez, Haya Alkiswani, Graham H. Litchman, Harrison Nguyen, Gil Yosipovitch, Firas George Hougeir, Matthew Zirwas, David Cotter, Brad Glick, E. James Song, Christopher G. Bunick, Neal Bhatia, Adam Friedman, Leon Kircik, Mona Shahriari, Peter Lio, James Del Rosso   +17 more
wiley   +1 more source

A Practical Guide for Incorporating Emollients in the Treatment of Mild‐to‐Moderate Atopic Dermatitis

JEADV Clinical Practice, EarlyView.
ABSTRACT Emollients and cleansers are essential components in managing atopic dermatitis (AD). While international evidence‐based guidelines recommend using gentle cleansers and emollients daily as a foundational therapy for AD, implementation in practice remains suboptimal.
Mette Deleuran, Wioletta Barańska‐Rybak, Michael J. Cork, Stamatis Gregoriou, Angela Hernandez‐Martin, Giuseppe Micali, Andaç Salman, Petra Staubach‐Renz, Antonio Torrelo, Charles Velter, Anneke Andriessen, Vanja Adzovic, Liselot Vink   +12 more
wiley   +1 more source

Dietary Patterns in Patients With Hidradenitis Suppurativa

JEADV Clinical Practice, EarlyView.
Among 131 patients, 99 had mild‐to‐moderate hidradenitis suppurativa and 25 severe HS. The most reported diets were “healthy and varied” or “no specific diet”, and 11% practiced intermittent fasting. Patients with mild‐to‐moderate HS reported similar frequency of intake of cake/biscuits/sweets, fast food, fish, vegetables and wholegrain as patients ...
Maria Victoria Gerdes‐Miranda, Marianne Bengtson Løvendorf, Simon Francis Thomsen, Lone Skov, Charlotte Näslund‐Koch   +4 more
wiley   +1 more source

Line‐Field Confocal Optical Coherence Tomography: A Diagnostic Tool Facilitating the Diagnosis of Sweet's Syndrome. A Case Report

JEADV Clinical Practice, EarlyView.
ABSTRACT Sweet's syndrome is a rare neutrophilic dermatosis characterized by an acute onset of erythematous and infiltrative lesions. Diagnosis is based on clinical, histopathological, and laboratory findings. We propose that non‐invasive skin imaging techniques, such as line‐field confocal optical coherence tomography (LC‐OCT), may be beneficial for ...
Aleksandra Anderson, Piotr Konopelski, Mariano Suppa, Joanna Czuwara, Marta Kurzeja, Lidia Rudnicka   +5 more
wiley   +1 more source

Triggering Receptor Expressed on Myeloid Cells‐2 Regulates Innate Lymphoid Cell Levels in Bleomycin‐Induced Pulmonary Fibrosis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Idiopathic pulmonary fibrosis, a pathological change causing poor outcomes, is not reversible despite current antifibrotic therapy. Emerging evidence suggests that innate lymphoid cells (ILCs) mediate lung inflammation and fibrosis after stimulation by endogenous factors.
Hsiao‐Chin Shen, Nien‐Jung Chen, Chuan‐Yen Sun, Wen‐Kuang Yu, Vincent Yi‐Fong Su, Wan‐Ling Yang, Wei‐Chih Chen, Kuang‐Yao Yang   +7 more
wiley   +1 more source

Pathophysiology of Pruritus in Atopic Dermatitis

Pruritus is a defining symptom of atopic dermatitis and has a tremendous impact on the quality of life of patients. The pathophysiology of pruritus in AD involves complex interactions between immune cells, cutaneous nerve fibers, and keratinocytes.
Yosipovitch, Gil, Soares, Georgia Biazus   +1 more
core   +1 more source

IGF2BP3 Overexpression Accelerates Osteoarthritis Progression by Promoting Glycolysis via m6A‐Dependent Stabilization of ECM1 mRNA

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT N6‐methyladenosine (m6A) plays a critical role in osteoarthritis (OA) pathogenesis. This study investigates the role of the m6A reader insulin‐like growth factor 2 mRNA‐binding protein 3 (IGF2BP3) in OA progression. OA models were established in vivo through destabilization of the medial meniscus (DMM) surgery in mice and in vitro by ...
Xing‐Shi Yuan, Hao‐Jie Zhang, Jia‐Xiang Ding, Zheng‐Liang Luo, Min Chen, Xiao‐Qi Zhang, Xi‐Fu Shang, Zhe Ni, Ke‐Rong Wu   +8 more
wiley   +1 more source

Treatment of atopic dermatitis with cyclosporin A: a case report

, 2017
Introduction . Despite the progress that has been made in the therapy of atopic dermatitis in recent years, cyclosporin A remains the first-line treatment of severe forms of the disease. Objective.
Adam Reich, Karolina Kaaz
core   +1 more source

Modern treatment methods in atopic dermatitis - literature overview

Journal of Education, Health and Sport
Introduction and aim: Atopic dermatitis (AD) is a chronic inflammatory skin disease. It is characterised by periods of exacerbation and remission of symptoms such as pruritus, dry skin and eczematous lesions with characteristic morphology.
Martyna Borowska-Łygan, Jakub Tomaszewski, Wojciech Urban, Konrad Strużek, Jan Biłogras, Kornelia Karamus, Rafał Wojciech Rejmak   +6 more
doaj   +1 more source

Patch test results in children and adolescents suffering from allergic contact dermatitis – comparison of patients with and without atopic dermatitis

, 2017
Introduction . Allergic contact dermatitis is a more and more frequently diagnosed skin disease in children and adolescents. It may coexist with atopic dermatitis.
Joanna Bacharewicz-Szczerbicka, Teresa Reduta, Anna Pawłoś, Iwona Flisiak   +3 more
core   +1 more source