Results 111 to 120 of about 144,049 (286)

Influence of the sebaceous gland density on the stratum corneum lipidome [PDF]

, 2018
The skin surface lipids (SSL) result from the blending of sebaceous and epidermal lipids, which derive from the sebaceous gland (SG) secretion and the permeability barrier of the stratum corneum (SC), respectively.
Camera, Emanuela, Kozul, Nina, Ludovici, Matteo, Materazzi, Stefano, Picardo, Mauro, Risoluti, Roberta   +5 more
core   +1 more source

Clinically Meaningful Improvements in Quality of Life, Including Sleep, With Two‐Week and Monthly Dosed Rademikibart: A Phase 2 Randomized Trial in Adults With Moderate‐to‐Severe Atopic Dermatitis

JEADV Clinical Practice, EarlyView.
Rademikibart, a potent IL‐4Rα‐targeting antibody, achieved its primary endpoint as a treatment for adults with moderate‐to‐severe atopic dermatitis (AD) in the CBP‐201‐WW001 Phase 2 trial. There is a need for AD treatment options with convenient dosing intervals.
Jonathan I. Silverberg, Emma Guttman‐Yassky, Raúl Collazo   +2 more
wiley   +1 more source

The positive effect of dupilumab on comorbid asthma in patients with atopic dermatitis

Clinical and Translational Allergy, 2023
Lotte S. Spekhorst, Marlies deGraaf, Lisa P. van derRijst, Nicolaas P. A. Zuithoff, René C. Schweizer, Marijke Kamsteeg, Inge Haeck, Anneke M. T. vanLynden‐van Nes, Paula vanLumig, Geertruida L. E. Romeijn, Marie‐Louise Schuttelaar, Marjolein S. deBruin‐Weller   +11 more
doaj   +1 more source

Prevalence and Burden of Somatic Symptom Disorder in Atopic Dermatitis and Chronic Pruritus—The Persistent Somatic Symptoms Across Diseases: Pruritus (SOMA.PRU) Study

JEADV Clinical Practice, EarlyView.
In adults with atopic dermatitis and chronic pruritus, the mental comorbidity of Somatic Symptom Disorder is associated with higher average and worst pruritus intensity, higher psychological distress and lower quality of life. Additionally, there were nonsignificant changes in cutaneous nerve fiber densities in skin biopsies.
Stefan M. Kahnert, Ansgar Koechel, Gina L. Frank, Svenja Royeck, Claudia Zeidler, Felix Witte, Christian Mess, Konstantin Agelopoulos, Volker Huck, Bernd Löwe, Rupert Conrad, Gudrun Schneider, Stefan W. Schneider, Sonja Ständer   +13 more
wiley   +1 more source

Causal association between atopic dermatitis and Parkinson's disease: A bidirectional Mendelian randomization study

Brain and Behavior
Background Atopic dermatitis is one of the most common skin disorders. Evidence has suggested an association between skin disorders, such as atopic dermatitis, and Parkinson's disease (PD).
Taofeng Zhou, Baohao Wei, Yachun Hu, Xiaoming Zhou, Xiaoying Cai, Xiaolei Shi   +5 more
doaj   +1 more source

Interplay of Staphylococcal and Host Proteases Promotes Skin Barrier Disruption in Netherton Syndrome. [PDF]

, 2020
Netherton syndrome (NS) is a monogenic skin disease resulting from loss of function of lymphoepithelial Kazal-type-related protease inhibitor (LEKTI-1).
Butcher, Anna M, Cau, Laura, Dupont, Christopher L, Gallo, Richard L, Horswill, Alexander R, Hovnanian, Alain, Kaul, Drishti, Khalil, Shadi, Sanford, James A, Wang, Yichen, Williams, Michael R, Zaramela, Livia S, Zengler, Karsten   +12 more
core  

Comparing Self‐Reported and Physician‐Assessed Acne Severity Using Real‐World Data

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Real‐world data (RWD) offers access to vast amounts of health information; however, limited knowledge exists regarding its reliability in clinical and research practices. Objectives To analyse the agreement between self‐assessed severity of self‐reported acne vulgaris (AV), and physician‐assessed severity based on photographic ...
Ali Al‐Mousawi, Somaia Naassan, Misbah Noshela Ghazanfar, Sarah‐Louise Leth Kirsten, Benóný Þór Björnsson, Christian Riemer, Simon Francis Thomsen, Zarqa Ali   +7 more
wiley   +1 more source

Patient‐Reported Outcomes Selected by Paediatric Patients With Atopic Dermatitis in the Aiming High in Eczema/Atopic Dermatitis Approach

JEADV Clinical Practice, EarlyView.
We surveyed 290 paediatric patients with atopic dermatitis (AD)/their caregivers to determine troublesome AD features described as PROs. The most selected were itch (0‐ to 5‐year‐old children: 85%; children aged ≥ 6 years: 89.3%), skin appearance/condition (69.9% and 61.6%, respectively), and sleep disturbance (38.1% and 25.4%, respectively ...
Yuji Fujita, Sayuri Kajitani, Manabu Miyamoto, Yusuke Ando, Masaya Kato, Hironobu Fukuda, Yumi Yamada, Nozomu Kitahara, Norimasa Fukuda, Hideaki Shiraishi, Shigemi Yoshihara   +10 more
wiley   +1 more source

Systemic Absorption and Pharmacokinetics of Five Novel Topical Dermatologic Agents: A Review

JEADV Clinical Practice, EarlyView.
ABSTRACT In recent years, innovative topical medications with novel mechanisms of action have emerged to treat common dermatologic conditions such as acne, atopic dermatitis, vitiligo, and actinic keratoses. These molecularly targeted therapies offer improved safety and tolerability compared to traditional options like corticosteroids.
Mary Dyson, Kara Hurley, Hannah Chaudhury, Lara Shehadeh, Cameron West   +4 more
wiley   +1 more source

ACTIVATED ZINC PYRITHIONE APPLICATION FOR THE ATOPIC DERMATITIS AMONG CHILDREN: MECHANISM OF ACTION, CLINICAL EFFICIENCY

Педиатрическая фармакология, 2009
Atopic dermatitis is characterized by the chronic recurrent course and often complicated by the consecutive infection and requires an adequate and regular external treatment. This article is devoted to the overview of the key pharmacodynamic and clinical
F.I. Petrovsky, D.S. Korostovtsev
doaj   +2 more sources