Atopic dermatitis (AD) is a highly pruritic, chronic inflammatory skin disease. The diagnosis is made using evaluated clinical criteria. Disease activity and burden are best measured with a composite score, assessing both objective and subjective ...
A. Wollenberg+27 more
semanticscholar +1 more source
Nomenclature and clinical phenotypes of atopic dermatitis
Atopic dermatitis is a heterogeneous disease and resists classification. In this review, we discuss atopic dermatitis nomenclature and identify morphologic phenotypes, which will facilitate correct diagnoses and development of treatment strategies.
G. Girolomoni+7 more
semanticscholar +1 more source
JAK3 as an emerging target for topical treatment of inflammatory skin diseases [PDF]
The recent interest and elucidation of the JAK/STAT signaling pathway created new targets for the treatment of inflammatory skin diseases (ISDs). JAK inhibitors in oral and topical formulations have shown beneficial results in psoriasis and alopecia ...
Alves de Medeiros, Ana+5 more
core +4 more sources
Proderm technology: a water- based lipid delivery system for dermatitis that penetrates viable epidermis and has antibacterial effects. [PDF]
BackgroundA defective skin barrier and bacterial colonization are two important factors in maintenance and progression of atopic dermatitis and chronic allergic/irritant hand dermatitis.
Caputo-Janhager, Melinda+4 more
core +3 more sources
Neutrophils promote CXCR3-dependent itch in the development of atopic dermatitis. [PDF]
Chronic itch remains a highly prevalent disorder with limited treatment options. Most chronic itch diseases are thought to be driven by both the nervous and immune systems, but the fundamental molecular and cellular interactions that trigger the ...
Barton, Gregory M+11 more
core +1 more source
Pollen grains induce a rapid and biphasic eczematous immune response in atopic eczema patients [PDF]
Introduction: Eczematous reactions to type I allergy-inducing antigens are documented in a subgroup of patients with atopic eczema. Yet, the underlying immunological mechanisms are not well understood.
Behrendt, Heidrun+7 more
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Skin Barrier Abnormalities and Immune Dysfunction in Atopic Dermatitis
Atopic dermatitis (AD) is a common and relapsing skin disease that is characterized by skin barrier dysfunction, inflammation, and chronic pruritus. While AD was previously thought to occur primarily in children, increasing evidence suggests that AD is ...
Gabsik Yang+5 more
semanticscholar +1 more source
A Microbiome-Based Index for Assessing Skin Health and Treatment Effects for Atopic Dermatitis in Children. [PDF]
A quantitative and objective indicator for skin health via the microbiome is of great interest for personalized skin care, but differences among skin sites and across human populations can make this goal challenging.
Callewaert, Chris+15 more
core +4 more sources
Atopic dermatitis and risk of autoimmune diseases: a systematic review and meta-analysis
Background Atopic dermatitis is the most common chronic inflammatory skin disease and presents a major public health burden worldwide. Recent observational studies revealed the potential association between atopic dermatitis with autoimmune disorders ...
Zhiyu Lu+7 more
semanticscholar +1 more source
Diagnostic Features of Atopic Dermatitis
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J. Hanifin, G. Rajka
semanticscholar +1 more source