Results 31 to 40 of about 74,225 (244)

Long‐Term Ocular Outcomes of Dupilumab in Atopic Dermatitis: Results From the BioDay Registry

Clinical and Translational Allergy
Background Dupilumab‐associated ocular surface disease (DAOSD) is the most reported side effect in dupilumab‐treated atopic dermatitis (AD) patients.
Nienke Veldhuis, Roselie E. Achten, Chantal M. vanLuijk, Marlot M. van derWal, Constance F. denHartog Jager, Nicolaas P. A. Zuithoff, Mohsin El Amrani, Edward F. Knol, Femke vanWijk, Marlies deGraaf, Inge M. Haeck, Mor M. Dickman, Marjolein S. deBruin‐Weller   +12 more
doaj   +1 more source

Nanomaterials for Allergy Diagnosis and Treatment: Advances, Opportunities and Translational Challenges

Advanced Science, EarlyView.
Nanomaterials offer dual applications in allergy management. For diagnosis, nanomaterials enhance analytical sensitivity and improve detection in specific IgE and functional assays such as the basophil activation test (BAT). For allergen‐specific immunotherapy, nanomaterials enable allergen masking and controlled release, and effectively modulate the ...
Madiha Habib, Shan Jiang, Joyce ZX Lee, CW Lim, HL Yeung, Nicki YH Leung, Patrick SC Leung, Ting F Leung, Christine YY Wai   +8 more
wiley   +1 more source

Complementary and Integrative Therapies for Childhood Atopic Dermatitis

Children, 2019
Background: Childhood atopic dermatitis is a chronic inflammatory skin condition that causes significant psychological and financial costs to the individual and society.
Adrienne L. Adler-Neal, Abigail Cline, Travis Frantz, Lindsay Strowd, Steven R. Feldman, Sarah Taylor   +5 more
doaj   +1 more source

AHR‐Responsive Carbon Dots Orchestrate Skin Wound Healing and Colonic Mucosal Repair via Treg‐Mediated Macrophage Efferocytosis

Advanced Science, EarlyView.
Guided by pharmacophore modeling and molecular docking, aryl hydrocarbon receptor (AHR)‐responsive carbon dots were synthesized. They bind directly to AHR and expand gut‐resident regulatory T (Treg) cells. Treg‐derived C‐C motif chemokine ligand 1 (CCL1) enhances macrophage efferocytosis, creating a pro‐regenetative niche that promotes colonic mucosal ...
Zilu Zhu, Han Zhang, Shuai Lin, Wenqian Zheng, Xin Li, Xiaowei Xu, Ruili Yang   +6 more
wiley   +1 more source

Redefining Treat-to-target in Atopic Dermatitis: Towards Meaningful, Patient-centred Disease Control – An ISAD Position Paper

Acta Dermato-Venereologica
Treat-to-target strategies link predefined goals to regular assessment and treatment adaptation. In atopic dermatitis, recent initiatives have mainly defined thresholds using clinician- and patient-reported outcomes.
John Su, Andreas Wollenberg, Melanie Funk, Tina Mesarič, Brandon Hu, Tammi Shipowick, Kelly Barta, Kristin Belleson, Li-Chuen Wong, Kiu Han Kim, Chia-Yu Chu, Sandipan Dhar, Yoshiyuki Kataoka, Kin Fon Leong, Kam Lun Ellis Hon, Erere Otrofanowei, Peter Foley, Lin Ma, Yong Kwang Tay, Marie Lodén, Anousha Yazdabadi, Kathrin A. Gibson, Jonathan D. Akikusa, Andrew Östör, Connie Katelaris, Frank Thien, Michihiro Futamura, Rie Yotsu, Peter Schmid-Grendelmeier, Alain Taïeb   +29 more
doaj   +1 more source

Does stress increase the risk of atopic dermatitis in adolescents? results of the Korea Youth Risk Behavior Web-based Survey (KYRBWS-VI). [PDF]

PLoS ONE, 2013
This study investigated the relationship between level of stress in middle and high school students aged 12-18 and risk of atopic dermatitis. Data from the Sixth Korea Youth Risk Behavior Web-based Survey (KYRBWS-VI), a cross-sectional study among 74,980
Jeoung A Kwon, Eun-Cheol Park, Minjee Lee, Ki-Bong Yoo, Sohee Park   +4 more
doaj   +1 more source

Upadacitinib Restrains the Pathogenic Fitness of CD4+ T Cells and Aberrant B Cell Programming in Optic Neuritis

Advanced Science, EarlyView.
Single‐cell profiling and functional perturbation reveal coordinated JAK1‐pSTAT3 downstream programs in optic neuritis, including MCL1‐dependent fitness of pathogenic CD4+ Tem cells and glycolysis‐linked, cholesterol‐sensitive B‐cell responses associated with RORA. Upadacitinib disrupts this reciprocal T‐B‐cell circuit and alleviates neuroinflammation,
Gengchen Jiang, Qi Jiang, Lian Han, Yue Peng, Xingyu Liu, Tong Yang, Hao Huang, Jiaying Liu, Yuan Gao, Hui Yang, Wenjun Zou, Zhaohuai Li, Wenru Su   +12 more
wiley   +1 more source

Suicidal Ideation in Adult Patients with Atopic Dermatitis: A German Cross-sectional Study

Acta Dermato-Venereologica, 2017
A cross-sectional study was performed to assess symptoms of suicidality, depression and anxiety in adult patients with atopic dermatitis. The study describes the relationships between these psychiatric symptoms and skin-specific factors, such as atopic ...
Jan Dieris-Hirche, Uwe Gieler, Frank Petrak, Wolfgang Milch, Bert te Wildt, Barbara Dieris, Stephan Herpertz   +6 more
doaj   +1 more source

ROS/pH‐Responsive Phenylboronic Acid–Chitosan Nanoparticles Improve Silymarin‐Mediated Hepatoprotection After Hepatectomy With Gut‐Liver Axis‐Associated Responses

Advanced Science, EarlyView.
Bioactive phenylboronic acid–chitosan nanoparticles enable responsive silymarin delivery for post‐hepatectomy liver protection. The nanoplatform integrates antioxidant and antibacterial functions, improves hepatic recovery, and is associated with coordinated shifts in gut microbiota, metabolites, cytokines, and hepatic proteomic pathways, suggesting a ...
Jinjin Tong, Chaochao Luo, Zezheng Liu, Xinyan Zhang, Daixu Jia, Yang Sun, Zhaonan Zhang, Haoran Shi, Jianfang Wang, Hua Zhang   +9 more
wiley   +1 more source

Green Synthesis of Silver Nanoparticles From Macaranga tanarius (L.) Mull. Arg. Leaf Extract With Enhanced Antibacterial, Antioxidant, and Tyrosinase Inhibitory Activities

International Journal of Microbiology
Atopic dermatitis (AD) is a chronic inflammatory skin disorder characterized by microbial imbalance, particularly the overgrowth of Staphylococcus aureus.
Hsin-Ya Yeh, Mohit Chand, Soma Sardar Barawi, Han-Chen Ho, Chia-Jyi Liu, Chih-Wei Chang, Higuchi Kazuki, Jui-Yu Chou   +7 more
doaj   +1 more source