Results 51 to 60 of about 144,049 (286)

Epidemiology of canine atopic dermatitis [PDF]

, 2007
Canine atopic dermatitis (CAD) is a chronic, allergic skin disease associated with IgE-mediated reactions to environmental allergens. Atopic dermatitis/eczema in humans shares many similarities with CAD and is an increasing problem in industrialized ...
Nødtvedt, Ane
core  

Safety and efficacy of fluticasone propionate in the topical treatment of skin diseases [PDF]

, 2004
Fluticasone propionate - the first carbothioate corticosteroid - has been classified as a potent anti-inflammatory drug for dermatological use. It is available as 0.05% cream and 0.005% ointment formulations for the acute and maintenance treatment of ...
Atsuta J, Boner AL, Bridgman A, Callen J, Delescluse J, Dooms-Goossens AE, Dykes PJ, Falcoz C, Fisher DA, Goossens A, Harding SM, Hogger P, James M, Johnson M, Johnson M, Juhlin L, Katz HI, Korting HC, Lebwohl M, Li JT, Liu XQ, Llewellyn-Jones CG, Lucky AW, McKenzie AW, McLean HM, Nurnberger FG, Phillipps GH, Roberts DT, Spencer CM, Tharp MD, Venning VA, Wilkinson SM, Wolkerstorfer A, Young MMR   +33 more
core   +1 more source

De Novo Design and Directed Evolution Refinement of Mirror‐Image Protein Binders Targeting Interleukin‐4

Advanced Science, EarlyView.
This study presents the de novo design and directed evolution of a mirror‐image D‐protein inhibitor targeting human interleukin‐4 (IL‐4). The engineered molecule exhibits nanomolar binding affinity for IL‐4 and effectively inhibits IL‐4–mediated signaling.
Liqing Xu, Yuxiang Ren, Tongyue Wang, Hongyong Li, Yue Yao, Lei Liu, Ke Sun, Peilong Lu   +7 more
wiley   +1 more source

Assessment of the severity of atopic dermatitis

Przegląd Dermatologiczny, 2016
Atopic dermatitis is a frequent, chronic and recurrent inflammatory skin disease with complex etiology. Typical symptoms of this disease are persistent itching and dry skin.
Agnieszka Bożek, Adam Reich
doaj   +1 more source

Gastrointestinal Manifestations in Rubinstein‐Taybi Syndrome

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Rubinstein–Taybi syndrome is a rare genetic condition associated with a wide range of physical, cognitive, and developmental impairments, yet its gastrointestinal manifestations remain poorly characterized. Case reports and small series suggest a high prevalence of gastroesophageal reflux, constipation, dysphagia, and nutritional compromise ...
Mohamad Abi Nassif, Ajay Kaul, Lev Dorfman, Khalil El‐Chammas   +3 more
wiley   +1 more source

Resolution of Refractory Multifocal Atrial Tachycardia in Costello Syndrome Using Trametinib: A Case Supporting MEK Inhibitors as Targeted, Specific Antiarrhythmic

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Arrhythmias affect approximately half of patients with Costello syndrome (CS, OMIM # 218040), with non‐reentrant atrial tachycardia being the most common. This case describes an infant with Costello syndrome carrying the pathogenic HRAS c.34G>A (p.G12S) variant who developed early‐onset, drug‐refractory multifocal atrial tachycardia (MAT ...
Vanina Taliercio, Annabelle Wilcox, Stacey Cole, Josue Flores Daboub, José E. Morales Moreno, Kasey G. Andrews, S. Yukiko Asaki, Thomas A. Pilcher, Martin Tristani‐Firouzi, Mary C. Niu, David Viskochil, Benjamin Hammond   +11 more
wiley   +1 more source

Case report: Dupilumab leads to an increased chance of head and neck Staphylococcus aureus infection in atopic dermatitis patients

Frontiers in Medicine, 2023
Dupilumab was the first biological medication licensed to treat atopic dermatitis (AD), and it has shown remarkable effectiveness and safety in the treatment of moderate-to-severe atopic dermatitis.
Min Chen, Kai Gao, Kamran Ali, Jinpeng Shan, YunMi Qiu, Tianci Xie, Yiling Yu, Liming Wu   +7 more
doaj   +1 more source

Report from the third international consensus meeting to harmonise core outcome measures for atopic eczema/dermatitis clinical trials (HOME). [PDF]

, 2014
This report provides a summary of the third meeting of the Harmonising Outcome Measures for Eczema (HOME) initiative held in San Diego, CA, U.S.A., 6-7 April 2013 (HOME III).
Admani, S, Aoki, V, Apfelbacher, C, Ardeleanu, M, Barbarot, S, Berger, T, Bergman, JN, Block, J, Borok, N, Burton, T, Chalmers, JR, Chamlin, SL, Deckert, S, DeKlotz, CC, Dohil, M, Eichenfield, LF, Graff, LB, Hanifin, JM, Hebert, AA, Humphreys, R, Katoh, N, Kisa, RM, Margolis, DJ, Merhand, S, Minnillo, R, Mizutani, H, Nankervis, H, Ohya, Y, Rodgers, P, Schmitt, J, Schram, ME, Simpson, EL, Singh, J, Spuls, P, Stalder, JF, Svensson, A, Takaoka, R, Teper, A, Thomas, KS, Tom, WL, von Kobyletzki, L, Weisshaar, E, Williams, HC, Zelt, S   +43 more
core   +1 more source

Dupilumab Beyond the Airway: Decreased Morbidity in a Real‐World Analysis

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Post hoc analyses of clinical trials have characterized dupilumab's adverse effects, yet the real‐world impact in chronic rhinosinusitis with nasal polyps (CRSwNP) and asthma is not well described. This study aims to characterize the risks of lymphoma, cardiovascular events, eosinophilia, joint pain, inflammatory arthritis, and ...
Emma J. Anisman, Spencer Short, Emma Tam, Benjamin F. Bitner, Abdulghafoor Alani, Marc Rosen, Mindy Rabinowitz, Damaris Pena Evertz, Elina Toskala, Gurston G. Nyquist   +9 more
wiley   +1 more source

Eco-Friendly Synthesis of Silver Nanoparticles Using Sapindus mukorossi Extract With Antibacterial and Photocatalytic Activities

Scientifica
Green synthesis of silver nanoparticles (AgNPs) offers an eco-friendly approach for developing multifunctional nanomaterials. In this study, AgNPs were synthesized using Sapindus mukorossi fruit extract as both reducing and stabilizing agents. UV–visible
Mohit Chand, Han-Chen Ho, Chia-Jyi Liu, Chih-Wei Chang, Higuchi Kazuki, Jui-Yu Chou   +5 more
doaj   +1 more source