Results 151 to 160 of about 2,245,775 (332)

The Evolving Landscape of Immunotoxicity: Charting Mechanisms and Future Strategies for Immune Checkpoint Inhibitor Adverse Events

Med Research, EarlyView.
ABSTRACT The use of immune checkpoint inhibitors (ICIs) has significantly improved the efficacy of cancer therapy, but their associated immune‐related adverse events (irAEs) can severely compromise treatment safety. This review systematically summarizes the core mechanisms underlying irAEs, which include multi‐organ damage resulting from T‐cell ...
Anqi Lin, Keyin Zheng, Aimin Jiang, Xufeng Huang, Qi Wang, András Hajdu, Zhengrui Li, Jian Zhang, Peng Luo   +8 more
wiley   +1 more source

Effectiveness of Ethanol Extract of Rosa rugosa Thunb. on Ear Edema

Molecular Nutrition &Food Research, EarlyView.
Rosa rugosa extract (RT50) exhibited anti‐inflammatory effects and promoted skin recovery in hypersensitive skin disorders. DNCB‐induced ear edema resulted in elevated levels of cytokines and chemokines while suppressing skin barrier‐related factors.
Seon Gyeong Bak, Nisansala Chandimali, Eun Jae Park, Seung Woong Lee, Jaehoon Bae, Mun‐Chual Rho, Seung Jae Lee   +6 more
wiley   +1 more source

Utilization of the Inpatient Dermatology Service at a Large Academic Medical Centre

JEADV Clinical Practice, EarlyView.
Allison Holt, Mike Westmeijer, Joseph Ebriani, Bethany Brumbaugh, Baraa Hijaz, Madeline E. DeWane, Michael Stephens, John Trinidad, Kevin Sheng‐Kai Ma, Daniela Kroshinsky, Steven T. Chen   +10 more
wiley   +1 more source

A 15‐year population‐based study on incidence and vaccination coverage in pediatric inflammatory bowel disease in Italy

Pediatric Investigation, EarlyView.
Increasing incidence of pediatric inflammatory bowel disease (IBD) and suboptimal vaccination coverage in Apulia, Italy (2009–2023). A total of 1044 incident cases of paediatric IBD were identified in the period 2009–2023 in Apulia, Italy, giving an average annual standardized incidence rate of 12.7/100 000. A significant increase in incidence occurred
Francesca Fortunato, Angelo Campanozzi, Michele Di Toma, Alessandra Marinari, Domenico Martinelli   +4 more
wiley   +1 more source

Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy

Phytotherapy Research, EarlyView.
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee, Yu Jin So, Il‐Joo Jo, Ji Yong Jang, Tae Han Yook, Jun Ho Lee, Sung Wook Kim, Kangwook Lee, Soo Jung Park, Gabsik Yang   +9 more
wiley   +1 more source

A Case of Palmoplantar Vesiculobullous Lesions

JEADV Clinical Practice, EarlyView.
Ali Abid, Kelvin Truong, Jing Jing Li, Artiene Tatian   +3 more
wiley   +1 more source

Smart Hydrogels in Wearable Electronics for Wound Treatments

Small, EarlyView.
This review explores how the integration of smart hydrogels with wearable electronics can revolutionize current wound care and advance the intelligent healthcare system. It highlights their dynamic responsiveness to the wound environment, innovative capabilities for real‐time biomarker monitoring, and various applications, emphasizing the enormous ...
Boyuan Li, Min Li, Yi Wang
wiley   +1 more source

Persistent Facial Nodules in an Elderly Patient

JEADV Clinical Practice, EarlyView.
Qian Ding, Qin‐Si Liu, Heng‐Guang Zhao   +2 more
wiley   +1 more source

Synthesis of Boronic Acid‐Functionalized Core–Shell Mesoporous Silica–TiO2 Nanocomposite for Specific Enrichment of Glycopeptides From Biological Samples

Small Methods, EarlyView.
The schematic illustrates a workflow showing the current investigation using a boronic acid‐functionalized core–shell mesoporous silica‐TiO₂ (CSMS@TiO₂‐GLYMO‐APB) for N‐glycopeptide enrichment from biological samples, involving trypsin digestion, enrichment, deglycosylation with PNGase F, and subsequent mass spectrometry (MALDI‐TOF MS and Nano‐LC‐MS/MS)
Mohamed Adly Gab‐Allah, Maryam Adelipour, Hyojin Hwang, Reham M. Marzouk, Heejin Lim, Jooyeon Oh, Ji‐Hyun Cha, Jaebeom Lee, Jeongkwon Kim   +8 more
wiley   +1 more source

Conductive Hydrogel‐Enabled Electrode for Scalp Electroencephalography Monitoring

Small Methods, EarlyView.
Conductive hydrogels are emerging as effective EEG electrode‐scalp interfaces to overcome hair barriers. This review presents the demanding parameters for hair‐compatible hydrogel electrodes and summarizes their applications in healthcare and brain‐computer interfaces.
Zichong Ji, Leqi Li, Meiqiong Zheng, Xinyuan Ye, Wenqing Yan, Zonglei Wang, Yi Liu, Yuli Wang, Yujie Zhang, Pengcheng Zhou, Jiawei Yang, Mingzhe Wang, Shihong Lin, Hossam Haick, Yan Wang   +14 more
wiley   +1 more source