ABSTRACT Background Frontal fibrosing alopecia (FFA) is an increasingly prevalent scarring alopecia potentially linked to environmental factors such as nanoparticles (NPs) in skincare and sunscreens. Objectives This case–control study aimed to quantify titanium, zinc, aluminum, and iron concentrations in hair shafts of FFA patients versus controls ...
Farnaz Ahmadpour +4 more
wiley +1 more source
Double‐Blind Placebo Challenge Confirmation of Diphenhydramine Allergy
ABSTRACT Diphenhydramine, a first‐generation H1–antihistamine commonly used for allergic symptom relief and infusion premedication, rarely causes true systemic hypersensitivity. When suspected reactions are mild and subjective—particularly in anxious patients—objective confirmation is essential.
Ruchi Patel +2 more
wiley +1 more source
Vandetanib induced photoallergic dermatitis: A case report
Vandetanib is a multi-kinase inhibitor of epidermal growth factor receptor (EGFR),vascular endothelial growth factor (VEGFR). Most common dermatological side effectsinduced by vandetanib include papulopustular eruption, hand-foot syndrome ...
Yüce, Gurbet Acar +7 more
core +1 more source
Outbreak of tropical rat mite (Ornithonyssus bacoti) dermatitis in a home for disabled persons [PDF]
Five mentally handicapped individuals living in a home for disabled persons in Southern Germany were seen in our outpatient department with pruritic, red papules predominantly located in groups on the upper extremities, neck, upper trunk and face.
Beck, W. +4 more
core +1 more source
Mechanisms and Regional Prevalence of Contact Allergens in Allergic Contact Dermatitis
Allergic contact dermatitis (ACD) represents a prevalent inflammatory skin condition resulting from exposure to environmental chemicals. The landscape of ACD has evolved significantly beyond traditional occupational settings, with widespread integration of allergens into cosmetics, consumer goods, and medical devices, creating new sensitization ...
Ji Young Um +5 more
wiley +1 more source
Filaggrin-stratified transcriptomic analysis of pediatric skin identifies mechanistic pathways in patients with atopic dermatitis [PDF]
Background: Atopic dermatitis (AD; eczema) is characterized by a widespread abnormality in cutaneous barrier function and propensity to inflammation. Filaggrin is a multifunctional protein and plays a key role in skin barrier formation.
Sherstnev, Alexander +13 more
core +1 more source
Modernizing U.S. Sunscreen Regulations: How Newer Filters Can Improve Public Health
ABSTRACT Background Skin cancer is the most common cancer in the United States, with over 5 million cases diagnosed annually. Despite being largely preventable, incidence rates continue to rise, largely due to inadequate protection from ultraviolet (UV) radiation, the primary environmental cause of skin cancer.
Clayton Wade Turner, Leslie Torgerson
wiley +1 more source
The Frequency and Causes of Photoallergic Contact Dermatitis among Dermatology Outpatients [PDF]
Too many patients with photoallergy remain undiagnoseddue to unsatisfactory knowledge among doctors and limited access tophotopatch testing. The objectives of this study were to analyze thefrequency of patients requiring diagnostic work-up for ...
Spiewak, Radoslaw +2 more
core +1 more source
Contact Urticaria and Related Conditions: Clinical Review
ABSTRACT Contact urticaria (CoU) is an immediate contact reaction occurring within minutes to an hour after exposure to specific proteins or chemicals. CoU is categorised into non‐immunologic (NI‐CoU) and immunologic (I‐CoU) types, with I‐CoU potentially leading to anaphylaxis. Both forms of CoU can be associated with protein contact dermatitis and the
Mojca Bizjak +15 more
wiley +1 more source
Synthesis Methods and Therapeutic Journey of Carprofen and Its Derivatives: A Review
Although it is currently only used in veterinary therapy, carprofen proves to be a molecule with a versatile therapeutic potential for human pharmacotherapy. Moreover, the molecule is a target in the drug discovery process for the development of new bioactive compounds.
Carmen Limban +6 more
wiley +1 more source

