Results 41 to 50 of about 576,280 (398)
JAK3 as an emerging target for topical treatment of inflammatory skin diseases [PDF]
, 2016 The recent interest and elucidation of the JAK/STAT signaling pathway created new targets for the treatment of inflammatory skin diseases (ISDs). JAK inhibitors in oral and topical formulations have shown beneficial results in psoriasis and alopecia ...
Alves de Medeiros, Ana +5 more
core +4 more sources
Neutrophils promote CXCR3-dependent itch in the development of atopic dermatitis. [PDF]
, 2019 Chronic itch remains a highly prevalent disorder with limited treatment options. Most chronic itch diseases are thought to be driven by both the nervous and immune systems, but the fundamental molecular and cellular interactions that trigger the ...
Barton, Gregory M +11 more
core +1 more source
British Journal of Dermatology, 2020 Tralokinumab is a fully human monoclonal antibody that specifically neutralizes interleukin‐13, a key driver of atopic dermatitis (AD).
J. Silverberg +11 more
semanticscholar +1 more source
By protecting against cutaneous inflammation, epidermal pigmentation provided an additional advantage for ancestral humans. [PDF]
, 2019 Pigmentation evolved in ancestral humans to protect against toxic, ultraviolet B irradiation, but the question remains: "what is being protected?" Because humans with dark pigmentation display a suite of superior epidermal functions in comparison with ...
Abuabara, Katrina +7 more
core +1 more source
Pollen grains induce a rapid and biphasic eczematous immune response in atopic eczema patients [PDF]
, 2008 Introduction: Eczematous reactions to type I allergy-inducing antigens are documented in a subgroup of patients with atopic eczema. Yet, the underlying immunological mechanisms are not well understood.
Behrendt, Heidrun +7 more
core +2 more sources
Methylisothiazolinone and Methylchloroisothiazolinone New Insights [PDF]
European Medical Journal Dermatology, 2013 Methylisothiazolinone (MI), along with Kathon™ CG (methylchloroisothiazolinone/MI), are widely used preservatives to prevent bacterial overgrowth in aqueous solutions of various types of cosmetic, household, and industrial products. Because of its high
Ana Rita Rodrigues-Barata +1 more
doaj
GENETIC AND THERAPEUTIC NOVELTIES IN ATOPIC DERMATITIS [PDF]
Romanian Journal of Medical Practice, 2018 Atopic dermatitis (atopic eczema) is a common affection in children, characterized by exacerbations and remissions. The forms may be mild, moderate or severe, the problem of treatment is in moderate and severe forms.
Ioana Veronica Grăjdeanu +5 more
doaj +1 more source
Pathophysiology of atopic dermatitis: Clinical implications.
Allergy and Asthma Proceedings, 2019 Atopic dermatitis (AD) is the most common chronic inflammatory skin disease. Genetic predisposition, epidermal barrier disruption, and dysregulation of the immune system are some of the critical components of AD.
Jihyun Kim, B. Kim, D. Leung
semanticscholar +1 more source
Epidemiology of atopic dermatitis in adults: Results from an international survey
Allergy. European Journal of Allergy and Clinical Immunology, 2018 There are gaps in our knowledge of the prevalence of adult atopic dermatitis (AD).
S. Barbarot +8 more
semanticscholar +1 more source
Contact Dermatitis, 2022 This review aims to provide a clinically useful update regarding the role of formaldehyde (FA) and its five main releasers (FRs) quaternium‐15, diazolidinyl urea, DMDM hydantoin, imidazolidinyl urea, and 2‐bromo‐2‐nitropropane‐1,3‐diol (bronopol) in ...
A. Goossens, O. Aerts
semanticscholar +1 more source