Results 11 to 20 of about 6,487 (164)

A Novel Topical Emollient Plus for Canine Atopic Dermatitis: A Clinical Trial Assessing Efficacy and User Acceptance. [PDF]

Vet Dermatol
Background: Canine atopic dermatitis (cAD) is a common, chronic skin condition characterised by epidermal barrier dysfunction, immune dysregulation and cutaneous dysbiosis. While “emollient plus” formulations are widely used in human atopic dermatitis, their role in cAD remains underexplored. Hypothesis/Objectives: To evaluate the clinical efficacy and
Fernandes B, Mendes AC, Alves SP, Schmidt V, Bizarro AF, Pinto M, Pereira H, Marto J, Lourenço AM.   +8 more
europepmc   +2 more sources

Efficacy of Der f 2/Zen 1-LAMP1 Plasmid-Based Vaccine Immunotherapy in Dogs With Atopic Dermatitis: A Proof-of-Concept Study. [PDF]

Vet Dermatol
Background: DNA‐based vaccination rapidly induces strong cellular and humoral immune responses, which may be enhanced by inclusion of lysosomal‐associated membrane protein‐1 (LAMP). Objectives: This proof‐of‐concept study evaluated the efficacy and safety of a Der f 2/Zen 1‐LAMP‐based DNA vaccine immunotherapy in client‐owned dogs with nonseasonal AD ...
Bizikova P, Matsumoto C, Ogino S, Tsukui T, Love K, Murphy M, Herrmann I.   +6 more
europepmc   +2 more sources

Randomised, Double-Blinded, Placebo-Controlled Challenge Test With Single Food Items in Dogs With Atopic Dermatitis and Adverse Food Reactions. [PDF]

Vet Dermatol
ABSTRACT Background Identification of offending foods in dogs with adverse food reactions is usually based on “deterioration” during open food challenges. Objectives To examine the placebo effect during double‐blinded, placebo‐controlled food challenges using a predefined set of criteria for relapse.
Sofou EI, Samuel E, Aleksandrova S, Chatzis M, Saridomichelakis MN.   +4 more
europepmc   +2 more sources

Machine Learning Model for an App-Based Tool to Assist With the Diagnosis of Canine Atopic Dermatitis. [PDF]

Vet Dermatol
Canine atopic dermatitis (cAD) is a chronic condition requiring life‐long management. Accurate diagnosis can be challenging, with no reliable diagnostic test. This study aimed to generate a simple diagnostic model for cAD. This model is a relevant prototype for an app‐based tool to support general practitioners in the diagnosis of cAD alongside ...
Langon X, Montoya M, Gourdon I.
europepmc   +2 more sources

Evaluation of filaggrin 2 expression in dogs with atopic dermatitis before and after oclacitinib maleate administration. [PDF]

Vet Dermatol
Background – Canine atopic dermatitis (cAD) is a chronic, inflammatory, multifactorial and pruritic disease. The presence of skin barrier impairment (e.g. filaggrin alterations), along with abnormal immune responses, can negatively impact cutaneous barrier function.
Villalobos WR, Ferreira T, Borek F, Santoro D, Ferrer L, Farias M.   +5 more
europepmc   +2 more sources

Effect of Gabapentin Administered With Prednisolone, Ciclosporin or a Placebo on Clinical Outcomes and Motor Activity in Cats With Atopic Skin Syndrome: A Prospective, Blinded, Placebo-Controlled Study. [PDF]

Vet Dermatol
Background: Gabapentin reportedly decreases central sensitisation, a disorder associated with chronic pruritus in humans, although this is not well documented in cats. Its combined use with the standard antipruritic therapy for feline atopic skin syndrome (FASS) is not yet described.
Morency J, Troncy É, Delsart A, Otis C, Del Castillo JRE, Gonzales A, Ross J, Moreau M, Pelletier JP, Martel-Pelletier J, Sauvé F.   +10 more
europepmc   +2 more sources

Effect of a Spray Containing Occlusive Agents, Humectants and Physiological Lipids on Skin Hydration of Healthy Dogs When Applied After Bathing With a Chlorhexidine 2%/Miconazole 2% Shampoo. [PDF]

Vet Dermatol
Background: Normal hydration of the canine epidermis is imperative for cutaneous homeostasis. Xerosis may be encountered in canine atopic dermatitis and may be aggravated by topical antiseptics. Hypothesis and Objectives: To evaluate the hydrating properties and the safety of a spray (Sensiderm spray; MP Labo) when applied after shampooing healthy dogs
Pseftogka A, Samuel Badulescu E, Chatzis MK, Saridomichelakis MN.   +3 more
europepmc   +2 more sources

Development of a Four-Language Questionnaire to Investigate Environmental Risk Factors for the Development of Canine Atopic Dermatitis and to Monitor Disease Course and Progression. [PDF]

Vet Dermatol
Background: The chronic and multifactorial character of canine atopic dermatitis (cAD) often leads to poor disease control and treatment dissatisfaction. Environmental factors are likely to contribute to the disease development and may play a more important role than assumed previously.
Rhodius PC, Fischer N, Rostaher A, Martini F, Chapman E, Audergon S, Hobi S, Lehner G, Wilhelm S, van Oordt N, Favrot C, Kowalska M.   +11 more
europepmc   +2 more sources

Incidence Rate of Otitis Externa Episodes in Atopic Dogs Is Reduced by a Therapeutic Diet in a 6-Month Randomised, Blinded, Controlled, Clinical Trial. [PDF]

Vet Dermatol
ABSTRACT Background Recurrent otitis externa (OE) episodes commonly affect dogs with canine atopic dermatitis (cAD) despite ongoing cAD treatment. Objective To determine if a therapeutic diet with active ingredients targeting the skin barrier and allergy pathways reduces the incidence rate of OE.
Watson A, Laxalde J, Martini F, Fischer N, Maina E, Favrot C.   +5 more
europepmc   +2 more sources

An open-label pilot study on an adsorbent mousse containing adelmidrol in client-owned cats with feline atopic skin syndrome and associated seborrhoea. [PDF]

Vet Dermatol
Background – Besides pruritus and skin lesions, cats with feline atopic skin syndrome (FASS) may have seborrhoea. Hypothesis/Objectives – The aim of this pilot study was to investigate whether an adsorbent mousse containing tapioca starch, adelmidrol and a nonpharmacological antimicrobial complex could decrease FASS‐associated seborrhoea in cats ...
Noli C, Della Valle MF, Morelli G, Schievano C, Skinalia Clinical Research Group.   +4 more
europepmc   +2 more sources