Results 151 to 160 of about 59,772 (269)

Production of hydroxyectoine from biogas by an engineered strain of Methylomicrobium alcaliphilum using a novel Taylor‐flow bioreactor

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND The production of compatible solutes, such as ectoine and hydroxyectoine, is of great interest due to their industrial and biotechnological applications. Methylomicrobium alcaliphilum was genetically engineered to replace a native gene with a heterologous one, aiming to enhance ectoine production.
Raquel Herrero‐Lobo, Nuria Fernández‐González, Eva Marcos, María Alejandra Martínez, Pedro García‐Encina, María del Rosario Rodero, Raúl Muñoz, Sergio Bordel   +7 more
wiley   +1 more source

Role of RNA modifications in carcinogenesis and carcinogen damage response

Molecular Carcinogenesis, Volume 62, Issue 1, Page 24-37, January 2023., 2023
Abstract The field of epitranscriptomics encompasses the study of post‐transcriptional RNA modifications and their regulatory enzymes. Among the numerous RNA modifications, N6‐methyladenosine (m6A) has been identified as the most common internal modification of messenger RNA (mRNA).
Michelle Verghese, Emma Wilkinson, Yu‐Ying He   +2 more
wiley   +1 more source

Epidermolysis bullosa for primary care providers: A practical review

Journal of General and Family Medicine, EarlyView.
Abstract Epidermolysis bullosa (EB) is a group of genetic skin diseases, which manifest as fragile skin and blistering in addition to many extracutaneous conditions. Pediatricians and primary care providers play an integral role in managing these patients with multifaceted care needs.
Kennedy Sparling, Judith O'Haver, Muayad Shahin, Amanda Damon, Nichole Halliburton, Kellie Badger, Mariam Iqneibi, Beth Moeves, Harper N. Price, Emily S. Gorell   +9 more
wiley   +1 more source

Best practices in surgical and nonsurgical management of head and neck Merkel cell carcinoma: An update

Molecular Carcinogenesis, Volume 62, Issue 1, Page 101-112, January 2023., 2023
Abstract Merkel cell carcinoma (MCC) is a rare, highly aggressive cutaneous neuroendocrine carcinoma. Controversy exists regarding optimal management of MCC as high‐quality randomized studies and clinical trials are limited, and physicians are bound to interpret highly heterogeneous, retrospective literature in their clinical practice. Furthermore, the
Daniela Duarte‐Bateman, Alan Shen, Taylor Bullock, Payam Sadeghi, Joseph M. Escandón, Eliska Dedkova, Brian R. Gastman   +6 more
wiley   +1 more source

Demonstration of autonomous fixed‐wing drone delivery of prescribed medications in remote islands in Japan

Journal of General and Family Medicine, EarlyView.
We demonstrated a combination of online medication counseling and drone delivery of medications dispensed by pharmacists in two rural clinics located far from pharmacies on remote islands in Japan. After being prescribed by physicians, dispensed by pharmacists, and online medication counseling, the medications were transported by autonomous fixed‐wing ...
Jun Miyata, Hironobu Tsuchiya, Fumiaki Nonaka, Yuji Aso, Masanori Sugahara, Takahiro Maeda   +5 more
wiley   +1 more source

Ustekinumab-Induced Vasculitis in a Patient With Crohn's Disease. [PDF]

ACG Case Rep J
Ospina Velasquez LE, Papadakis KA, Urquhart SA.   +2 more
europepmc   +1 more source

ANTIBIOTICS USED AS ANTI-INFLAMMATORY AND IMMUNOMODULATORY AGENTS IN DERMATOLOGICAL DISORDERS

, 2018
Showkath Ali S, Tantradi Praveena, Madhavi Lata M, Mastan Saheb   +3 more
openalex   +1 more source

Characterization of health concerns in people with neurofibromatosis type 1

Molecular Genetics &Genomic Medicine, Volume 11, Issue 1, January 2023., 2023
NF1 is a common cancer predisposition syndrome that requires lifelong surveillance. The aim of this research was to characterize health concerns and QoL in a population cohort. This study highlights that the presence of itch and increased visibility of NF1 complications impacts the QoL of adults and children.
Jane Fleming, Oliver Morgan, Claire Wong, Timothy E. Schlub, Yemima Berman   +4 more
wiley   +1 more source

First cycle toxicity and survival in patients with rare cancers treated with checkpoint inhibitors. [PDF]

J Natl Cancer Inst
Othus M, Patel SP, Chae YK, Dietrich E, Streicher H, Sharon E, Kurzrock R.   +6 more
europepmc   +1 more source

Real‐life retrospective multicentre study to describe the use of dupilumab in paediatric patients with atopic dermatitis in Spain: Patient profile, effectiveness and safety

JEADV Clinical Practice, EarlyView.
Abstract Background Dupilumab, inhibiting interleukin 4 and 13, is the first monoclonal antibody licensed for atopic dermatitis (AD) since 6 months of age. Objectives The study describes the patients' profile, the effectiveness and safety in real life of dupilumab in adolescents with moderate‐severe AD and children with severe AD.
Eulalia Baselga Torres, Marta Ivars, Carolina Prat, Asunción Vicente, Marta Feito Rodríguez, Rocío Maseda Pedrero, Ana Martín Santiago, Aniza Giacaman, Antonio Torrelo Fernández, Lucero Noguera‐Morel, Isabel Betlloch Mas, Laura de Berbegal Gracia, Montserrat Évole Buselli, Mónica Pozuelo Ruiz, José Bernabéu Wittel, María T. Monserrat García, Minia Campos Domínguez, Cristina Galache Osuna, Jorge Santos‐Juanes Jiménez, Altea Esteve Martínez, Violeta Zaragoza Ninet, Miquel Casals Andreu, Sara I. Palencia Pérez, José Suárez Hernández, Sara Dorta Alom, Laura Feliciano Divasson, Ana Batalla Cebey, Manuel Galán Gutiérrez, Raúl de Lucas Laguna   +28 more
wiley   +1 more source