Results 71 to 80 of about 28,315 (303)
Dysregulation of the PATZ1/CTCF Balance Silences ZBTB20 to Drive Melanoma Progression
Advanced Science, EarlyView.This study uncovers a new oncogenic mechanism in melanoma. The transcription factor PATZ1 competes with the architectural protein CTCF for DNA binding, thereby disrupting a specific chromatin loop and silencing the tumor suppressor ZBTB20. This event unleashes the pro‐tumorigenic PMEPA1‐p38‐STAT1 signaling axis, promoting cancer progression.
Chaowei Deng +8 more
wiley +1 more source
Bullous hemorrhagic lichen sclerosus of the breast: a report of two cases and review of the literature [PDF]
, 2019 Lichen sclerosus (LS) is a chronic dermatologic condition characterized by atrophic porcelain-appearing plaques that can cause intense discomfort and eventually lead to destruction of local architecture.
Kroger, Kathleen T +3 more
core
Advanced Science, EarlyView.A dual‐targeting strategy to rejuvenate aged tendons. A reactive oxygen species (ROS)‐responsive hydrogel co‐delivers a selenium nanozyme (scavenges ROS) and a STING inhibitor to tendon stem cells. This combined action restores mitochondria–nucleus communication, alleviates cellular senescence, and rejuvenates tendon regeneration, offering a novel ...
Zhuo Zhang +11 more
wiley +1 more source
Jefferson Digital Commons quarterly report: October-December 2017 [PDF]
, 2018 This quarterly report includes: Assorted assets added to the JDC in the last quarter Grand Rounds Recordings College Within a College (CWIC) Posters Program of Industrial Design Capstones What people are saying about the ...
Copeland, James, LIBT +2 more
core +1 more source
Advanced Science, EarlyView.This study identifies the cockroach‐derived peptide leucokinin VIII as a potent accelerator of diabetic wound healing. By activating the FAK‐ACTG1 axis, the peptide drives keratinocyte migration and filopodia formation. Delivered via a developed PLGA‐PEG‐PLGA thermosensitive hydrogel for sustained release, this approach significantly hastens wound ...
Zhengshan Qin +11 more
wiley +1 more source
Understanding methods of wound debridement [PDF]
, 2014 Autolytic debridement describes the body's natural method of wound-bed cleansing, helping it to prepare the wound bed for healing. In acute wounds, autolytic debridement occurs automatically and often does not require intervention, as during the ...
Broadus C +5 more
core +1 more source
Multimodal Wearable Biosensing Meets Multidomain AI: A Pathway to Decentralized Healthcare
Advanced Science, EarlyView.Multimodal biosensing meets multidomain AI. Wearable biosensors capture complementary biochemical and physiological signals, while cross‐device, population‐aware learning aligns noisy, heterogeneous streams. This Review distills key sensing modalities, fusion and calibration strategies, and privacy‐preserving deployment pathways that transform ...
Chenshu Liu +10 more
wiley +1 more source
EFEKTIVITAS SALEP JINTAN HITAM (Nigella Sativa) PADA PROSES PENYEMBUHAN LUKA PERINEUM RUPTURE IBU NIFAS [PDF]
, 2016 Latar Belakang : Penyebab kematian maternal di Indonesia terkait persalinan adalah infeksi 11% berawal dari penatalaksanaan ruptur perineum yang kurang baik.
KUNTJORO, Tjahjono +2 more
core
De novo head and neck cancer after liver transplant with antibody-based immunosuppression induction [PDF]
, 2018 Background Powerful antibody-based immunosuppression induction is now used routinely during organ transplantation, and may place patients at even higher risk of post-transplant cancer.
Graham, Ryan C. +2 more
core +1 more source