Results 121 to 130 of about 392,833 (299)

The Nuclear Receptor Testicular Receptor 4 Orchestrates Cytoskeletal Organization in a G Protein Subunit Alpha 12/Rho‐Associated Protein Kinase–Dependent Manner to Promote Myofibroblast Differentiation and Tissue Fibrosis in Systemic Sclerosis

Arthritis &Rheumatology, EarlyView.
Objective Members of the superfamily of nuclear receptors have been implicated in inflammatory processes and pathologic tissue remodeling and have emerged as attractive targets for pharmaceutical intervention. However, the role of testicular receptor 4 (TR4; or Nr2c2) in fibroblast activation and rheumatologic diseases has not yet been investigated ...
Yun Zhang, Lichong Shen, Junhui Zheng, Gisela Baur, Dilidaer Yasen, Honglin Zhu, Yi‐Nan Li, Xianyi Meng, Thuong Trinh‐Minh, Tim Filla, Debomita Chakraborty, Andrea‐Hermina Györfi, Christina Bergmann, Adam Reich, Alexander Kreuter, Georg Schett, Jörg H. W. Distler   +16 more
wiley   +1 more source

A Deep Learning-Based Automated Scoring System for Predicting Eyelid Rejuvenation Outcomes After Monopolar Radiofrequency Treatment

Clinical, Cosmetic and Investigational Dermatology
Dong Hye Suh,1 Sang Jun Lee,1 In Yong Kim,2 Byung Chul Jang,3 Hei Sung Kim4 1ArumdaunNara Dermatologic Clinic, Seoul, Korea; 2Switz Dermatologic Clinic, Seoul, Korea; 3School of Electronics and Electrical Engineering, Kyungpook National University, Daegu,
Suh DH, Lee SJ, Kim IY, Jang BC, Kim HS
doaj  

Facial Cutaneous Rosai-Dorfman Disease Misdiagnosed as Sporotrichosis: A Case Report and Literature Review

Clinical, Cosmetic and Investigational Dermatology
Xinhuan Wang, Ji Li, Zhihao Li, Yuan Chen, Yubei Li, Xiaodong Li,* Yang Han* Department of Dermatology, Affiliated Central Hospital of Shenyang Medical College, Shenyang, Liaoning, People’s Republic of China*These authors ...
Wang X, Li J, Li Z, Chen Y, Li Y, Li X, Han Y   +6 more
doaj  

Nonmelanoma Skin Cancer Risk With JAK Inhibitors Compared to Interleukin‐6 Receptor Inhibitors in Rheumatoid Arthritis: Results From a National Cohort Study

Arthritis &Rheumatology, EarlyView.
Objective Nonmelanoma skin cancer (NMSC) is one of the most common malignancies in rheumatoid arthritis (RA). This analysis assessed NMSC risk with JAK inhibitors (JAKi) compared to interleukin‐6 receptor inhibitors (IL‐6Ri). Methods This study used data from the British Society for Rheumatology Biologics Register for Rheumatoid Arthritis linked to the
Zixing Tian, Lianne Kearsley‐Fleet, Sizheng Steven Zhao, James Galloway, Mark Lunt, Kath Watson, Narges Azadbakht, British Society for Rheumatology Biologics Register in Rheumatoid Arthritis Contributors Group, Kimme L. Hyrich   +8 more
wiley   +1 more source

Fibronectin-Based Skin Care Regimens for Skin Recovery After Intense Pulsed Light Therapy: A Split-Face Study

Clinical, Cosmetic and Investigational Dermatology
Haixia Feng,1,* Lan Ge,2,* Ge Shi,3,4,* Shan Yu,5 Xin Wang,6 Xiaowei Li,7 Si Wen,8 Linshan Wu,8 Zhen Yi,8 Xuesong Xian,8 Xiaoyan Fu,8 Baihui Zhang,8 Jinyin Liang,8 Hongling Zhu,8 Li Ye8 1Department of Dermatology, The University ...
Feng H, Ge L, Shi G, Yu S, Wang X, Li X, Wen S, Wu L, Yi Z, Xian X, Fu X, Zhang B, Liang J, Zhu H, Ye L   +14 more
doaj  

Deucravacitinib in Active Psoriatic Arthritis: Efficacy and Safety Up to 52 Weeks From the Randomized, Double‐Blind, Phase 3 POETYK PsA‐2 Trial

Arthritis &Rheumatology, EarlyView.
Objective To assess the efficacy and safety of deucravacitinib, an oral, selective tyrosine kinase 2 inhibitor, in patients with psoriatic arthritis (PsA) who were naive to biologic disease‐modifying antirheumatic drugs or received tumor necrosis factor inhibitors. Methods In the 52‐week, double‐blind, placebo‐controlled, phase 3 Program for Evaluation
Philip J. Mease, Vinod Chandran, April W. Armstrong, Ricardo Blanco, Alexis Ogdie, Evan L. Siegel, Alice B. Gottlieb, Xiaofeng Zeng, Diamant Thaçi, Mitsumasa Kishimoto, Hendrik Schulze‐Koops, Alan Kivitz, Eva Dokoupilová, Akimichi Morita, Eric M. Ruderman, Michael Plewinski, Kejia Wang, Caroline Sardinas, Eleni Vritzali, John Vaile, Atul Deodhar   +20 more
wiley   +1 more source

Integrative Multi-Omics and Experimental Analyses Identify TAPBP as a Key Mediator Linking Genetic Susceptibility to Melanocyte Dysfunction in Vitiligo

Clinical, Cosmetic and Investigational Dermatology
Jinlong Shi,1,* Mingzhen Guo,2,* Liying Fu,1 Jiangman He,1 Yuan Hu3 1Department of Dermatology, Zhengzhou People’s Hospital, Zhengzhou, Henan, People’s Republic of China; 2Department of Laboratory, Women and Children’s Hospital Affiliated
Shi J, Guo M, Fu L, He J, Hu Y
doaj  

Anti–Carbamylated Fibrinogen Autoantibodies of IgG and IgA Isotypes Contribute to a Better Prognostic Stratification in Very Early Rheumatoid Arthritis: Data From the French National ESPOIR Cohort

Arthritis &Rheumatology, EarlyView.
Objective The aim of this study was to investigate the prevalence and longitudinal evolution of anti–carbamylated fibrinogen antibodies (ACa‐Fib) of IgG and IgA isotypes in early rheumatoid arthritis (RA) and determine whether these antibodies provide additional diagnostic and prognostic information beyond anti–cyclic citrullinated peptide (anti‐CCP ...
Pauline Brevet, Olivia Guérin, Léna Le Goaréguer, Élisa Halbourg, Marie‐Laure Golinski, Sophie Candon, Olivier Boyer, Thierry Lequerré, Thierry Schaeverbeke, Valérie Devauchelle‐Pensec, Olivier Vittecoq, Manuel Fréret   +11 more
wiley   +1 more source

Bidirectional Inflammatory Mechanisms and Hematological/Coagulation Dysregulation in Psoriasis Complicated with Atherosclerosis: A Retrospective Hospital-Based Case-Control Study Leveraging the SH-YIMED Clinical Database

Psoriasis: Targets and Therapy
Miao Zhang,1,2,* Munsoon Hong,3,4,* Ruiqing Cao,1,2,* Jiale Chen,1,2 Liu Liu,1,2 Xiaoying Sun,1,2 Seokgyeong Hong,1,2 Xin Li1,2 1Department of Dermatology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine ...
Zhang M, Hong M, Cao R, Chen J, Liu L, Sun X, Hong S, Li X   +7 more
doaj  

Age‐Associated B Cells Contribute to Inflammation Via Antibody‐Independent Mechanisms in Takayasu Arteritis

Arthritis &Rheumatology, EarlyView.
Objective Although Takayasu arteritis (TAK) is not a prototypical autoantibody‐mediated disease, accumulating evidence suggests that B cells are involved. This study aimed to investigate the pathway of B cell activation and its contributions to TAK pathogenesis. Methods Histologic analysis of paravascular lymph nodes and affected arteries was conducted
Chenglong Fang, Xiaoxi Yang, Xiaochuan Sun, Shangyi Jin, Lihong Du, Jinwei Gao, Jing Li, Zhen Chen, Yuexin Chen, Mengtao Li, Xinping Tian   +10 more
wiley   +1 more source