Results 101 to 110 of about 392,833 (299)

Oral minoxidil bio-activation by hair follicle outer root sheath cell sulfotransferase enzymes predicts clinical efficacy in female pattern hair loss

, 2019
Department of Dermatology and Radiotherapy São Paulo State University – UNESPApplied Biology Inc.Sinclair DermatologyDepartment of Dermatology and Radiotherapy São Paulo State University ...
Ramos, P. M. [UNESP], Sinclair, R., Miot, H. A. [UNESP], Goren, A.   +3 more
core   +1 more source

When Biology Meets Medicine: A Perspective on Foundation Models

Advanced Intelligent Discovery, EarlyView.
Artificial intelligence, and foundation models in particular, are transforming life sciences and medicine. This perspective reviews biological and medical foundation models across scales, highlighting key challenges in data availability, model evaluation, and architectural design.
Kunying Niu, Yuxing Wang, Limin Zou, Jing Huang   +3 more
wiley   +1 more source

Evaluating Baricitinib for Severe Paediatric Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) with Single-Cell Sequencing

Journal of Inflammation Research
Danyang Yang,1 Xin Liu,1 Wenwen Jing,1 Xu Feng,1 Canying Lai,1 Chenyue Liu,2 Zhigang Xu,1,3 Yangang Zhang,1 Jiayi Han,1 Songmei Geng,1 Ruilian Li,1 Dan Li,4 Boyi Cheng,1 Yufei Wu,1 Zhuokun Liu,1 Jialin Lian,1 Zhenghui Wang,5 Yale Liu,1,* Xiaoli ...
Yang D, Liu X, Jing W, Feng X, Lai C, Liu C, Xu Z, Zhang Y, Han J, Geng S, Li R, Li D, Cheng B, Wu Y, Liu Z, Lian J, Wang Z, Liu Y, Li X   +18 more
doaj  

The EXPLAIN Study: Exploring Arthrogryposis Multiplex Congenita in Adults in Norway — A Description of Demographic, Medical, and Neurological Findings

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Arthrogryposis Multiplex Congenita (AMC) encompasses several hundred conditions with diverse genetic, pathophysiological, and clinical origins. The overarching EXPLAIN study explores underlying causes and implications of AMC and represents the largest clinical cohort of adults with AMC reported to date.
My Vuong Hermansen, Kristin Ørstavik, Unni Steen, Mathias Toft, Cathrine Brunborg, Lena Lande Wekre   +5 more
wiley   +1 more source

Oral Acitretin Combined with Topical 0.1% Tretinoin Cream for Facial Basal Cell Carcinoma in an Elderly Patient: A Case Report

Biologics: Targets & Therapy
Zhirong Shu,1,2,* Yu Jiang,1,2,* Shilin Deng,1,2 Tingnan Chen,1,2 Jingyao Liang,1,2 Xibao Zhang1,21Institute of Dermatology, Guangzhou Medical University, Guangzhou, 510095, People’s Republic of China; 2Department of Dermatology ...
Shu Z, Jiang Y, Deng S, Chen T, Liang J, Zhang X   +5 more
doaj  

Body dysmorphic disorder in female Swedish dermatology patients

, 2017
BackgroundIndividuals with body dysmorphic disorder (BDD) are highly distressed and impaired owing to perceived defects in their physical appearance that are not noticeable to others.
Klaas Wijma, Brohede, Sabina, Gun Wingren, Wijma, Klaas,, Sabina Brohede, Wyon, Yvonne, Wyon, Yvonne,, Yvonne Wyon, Wingren, Gun, Barbro Wijma, Brohede, Sabina,, Wijma, Klaas, Wijma, Barbro, Wingren, Gun,, Wijma, Barbro,   +14 more
core   +1 more source

Construction and evaluation of a chronic arthritis animal model induced by persistent activation of toll‐like receptors via lipopolysaccharide stimulation

Animal Models and Experimental Medicine, EarlyView.
We constructed a novel systemic juvenile idiopathic arthritis mouse model (LC) by introducing sustained TLR4 activation into the collagen‐induced arthritis model. The LC model effectively recapitulates human sJIA‐like systemic inflammation while revealing a critical dissociation between systemic immune activation and joint damage.
Fengming Li, Qiang Luo, Xinglin Wu, Yuxiao Chen, Xuemei Tang   +4 more
wiley   +1 more source

Associations of Sleep Quality and Perceived Stress with Skin, Scalp, and Hair Health Among 1,017 Chinese Women: A Cross-Sectional Observational Study

Clinical, Cosmetic and Investigational Dermatology
Shanqing Wang1,*, Ping Wang2,*, Juan Liu2,*, Lihong Chen1, Peggy Sextius3, Nathalie Deshayes3, Chengda Ye2, Frederic Flament4, Stephanie Nouveau3, Jun Wu2, Xingyuan Wang2, Zeneng Sun2, Yu Gao2, Emmanuelle Mainguene5, Jie Qiu2, Meng Pan1 1Department of ...
Wang S, Wang P, Liu J, Chen L, Sextius P, Deshayes N, Ye C, Flament F, Nouveau S, Wu J, Wang X, Sun Z, Gao Y, Mainguene E, Qiu J, Pan M   +15 more
doaj  

Circulating Exosomes Drive Persistent Neuronal Dysfunction in Post‐Herpetic Neuralgia Patients

Annals of Neurology, EarlyView.
Proposed model of exosome‐mediated neuronal dysfunction in post‐herpetic neuralgia (PHN). (1) Circulating, non‐pathogenic exosomes maintain homeostatic processes in healthy skin, where sensory nerve fibers innervate the epidermis and dermis. (2) During acute zoster, reactivating varicella zoster virus (VZV) travels down neurites to the skin causing ...
Christy S. Niemeyer, Seth Frietze, Serena W.R. Lewis, Emily C. Artman, Christina Coughlan, Safa I. Vaseemuddin, Arianna Gentile Polese, Maria A. Nagel, Stephen K. Tyring, Fyona Okundia, Anthony J. Saviola, Gary C. Curhan, Sharon G. Curhan, Diego Restrepo, Andrew N. Bubak   +14 more
wiley   +1 more source

Nanostructured Deep Eutectic Systems in Healthcare: From Bioactive Solvents to Intelligent Biointerfaces, Wearables, and AI‐Driven Design

Advanced NanoBiomed Research, EarlyView.
Beyond the green solvent paradigm, this review redefines Deep Eutectic Systems (DES) as programmable supramolecular nanoassemblies. We survey their biomedical convergence: stabilizing thermolabile mRNA to enable cold chain‐free logistics, reshaping transdermal microneedle delivery, enabling long‐term wearables via eutectogels, and utilizing Generative ...
Jeesu Moon, Min Seo Kim, Jae‐Seung Lee
wiley   +1 more source