Results 91 to 100 of about 392,833 (299)

The Saudi National Policy and Protocol for Epidermolysis Bullosa

open access: yesRisk Management and Healthcare Policy
Ashjan Alheggi,1,* Amal Alhashem,2,3,* Hind Mohammad H Alshihry,4,* Sultan Al-khenaizan,5,* Fawwaz Freih Alshammrie,6,* Mariam M AlEissa,7– 10,* Hajer Y Almudaiheem,11,* Nancy Shehata,12,&ast ...
Alheggi A   +13 more
doaj  

Single‐Nucleus Transcriptomic Atlas of Human Vellus Hair Pilosebaceous Units Reveals Age‐Associated Remodeling

open access: yesAdvanced Science, EarlyView.
Human vellus pilosebaceous units (PSUs) remain uncharted. This single‐nucleus atlas reveals coordinated remodeling of the aging PSU niche: reduced bulge stem cell representation with altered regenerative programs, increased representation of a stress‐responsive channel+ epithelial state, enhanced androgen‐responsive sebaceous programs, reduced ...
Ya'nan Li   +9 more
wiley   +1 more source

A Case Report of Necrolytic Migratory Erythema Associated with Glucagonoma

open access: yesClinical, Cosmetic and Investigational Dermatology
Di Xia,* Zhouliang Liu,* Jiamin Li, Jingjing Liu, Yongbin Qu Dermatology Hospital of Southern Medical University, Southern Medical University, Guangzhou, People’s Republic of China*These authors contributed equally to this ...
Xia D, Liu Z, Li J, Liu J, Qu Y
doaj  

Lipid Metabolic Dysregulation Driven by OSMR Mutations Underlies Amyloidogenesis in Primary Localized Cutaneous Amyloidosis

open access: yesAdvanced Science, EarlyView.
OSMR mutations disrupt STAT5 signaling and AKR1B10‐mediated lipid metabolism, leading to lipid accumulation and protein aggregation in keratinocytes. This metabolic reprogramming drives amyloid deposition in primary localized cutaneous amyloidosis, revealing a mechanistic link between lipid dysregulation and amyloidogenesis.
Huiting Liu   +8 more
wiley   +1 more source

Intermolecular Carbon–Carbon Naphthalene Coupling Involves a Radical Mechanism Driven by Cytochrome P450 in Alternaria alternata

open access: yesAngewandte Chemie, EarlyView.
1,8‐DHN is an important intermediate to form complex aromatic ring systems. Phenol‐coupling reactions are important for the dimerization of two molecules. Here, we show that a fungal cytochrome P450 enzyme catalyzes specific C─C bonds. ABSTRACT Dihydroxynaphthalene (DHN) derivatives are precursors of biologically important molecules, including melanin ...
Jia Gao   +8 more
wiley   +2 more sources

The Pendulum of Adherence: An Interpretative Phenomenological Analysis of Psoriasis Treatment Discontinuation

open access: yesPatient Preference and Adherence
Zhanshuo Xiao,1,* Yilin Jiang,2,* Narina A Samah,2,* Heng Zhou,3 Junhui Wang1 1Department of Dermatology, Guanganmen Hospital, Beijing, 100053, People’s Republic of China; 2Faculty of Educational Sciences and Technology, Universiti Teknologi ...
Xiao Z   +4 more
doaj  

An Adenoviral‐Vectored Tp0326 Vaccine Elicits Robust Functional Antibodies to Prevent Treponema pallidum Dissemination in a Rabbit Model

open access: yesAdvanced Science, EarlyView.
Vaccination promotes cellular infiltration into primary lesions and effectively inhibits T. pallidum dissemination to distal organs. Notably, transfer of lesion tissue from immunized animals fails to establish infection in naive recipients, confirming specific protective immunity.
Yinbo Jiang   +4 more
wiley   +1 more source

Safety and Efficacy of Hyaluronic Acid-Based Filler for Neck Wrinkles: A Prospective, Multicenter, Randomized, Parallel-Controlled Non-Inferiority Trial

open access: yesClinical, Cosmetic and Investigational Dermatology
Meng Jiang,1 Haiyan Cheng,1 Yan Li,1 Hongmei Ai,2 Jun Li,3 Yanjun Liang,4 Wei Xu1 1Department of Dermatology and Venereology, Beijing Friendship Hospital, Capital Medical University, Beijing, People’s Republic of China; 2Department of Plastic Surgery ...
Jiang M   +6 more
doaj  

Autonomous AI‐Driven Design for Skin Product Formulations

open access: yesAdvanced Intelligent Discovery, EarlyView.
This review presents a comprehensive closed‐loop framework for autonomous skin product formulation design. By integrating artificial intelligence‐driven experiment selection with automated multi‐tiered assays, the approach shifts development from trial‐and‐error to intelligent optimisation.
Yu Zhang   +5 more
wiley   +1 more source

A Case Report of a Rare Subacute Cutaneous Lupus Erythematosus with Chin Prostration

open access: yesClinical, Cosmetic and Investigational Dermatology
Wanni Li,1,2,* Wen Luo,1,* Yujia Liang,1,2 Ping Wang,1,2 Chunxia Wang,1,2 Jiejie Lu,1,2 Weiwei Wu1,2 1Department of Dermatology, Affiliated Dermatology Hospital of Hainan Medical University, Haikou, People’s Republic of China; 2Department
Li W   +6 more
doaj  

Home - About - Disclaimer - Privacy