Results 41 to 50 of about 348,332 (257)

Implantable Microarray Patch: Engineering at the Nano and Macro Scale for Sustained Therapeutic Release via Synthetic Biodegradable Polymers

open access: yesAdvanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
This review focuses on the application of synthetic biodegradable microarray patches (MAPs) in sustained drug delivery. Compared to conventional MAPs which release drugs into the skin in an immediate manner, these implantable MAPs release drugs into skin microcirculation gradually as the biodegradable polymers degrade, thus offering sustained release ...
Li Zhao   +6 more
wiley   +1 more source

Remote‐Controlled Wireless Bioelectronics for Fluoxetine Therapy to Promote Wound Healing in a Porcine Model

open access: yesAdvanced Materials Technologies, EarlyView.
A wireless bioelectronic ion pump platform is developed for controlled fluoxetine delivery for wound healing in a large mammal model. Over 3 days, treated wounds showed 37% greater re‐epithelialization and a 33% lower ratio of pro‐inflammatory to reparative macrophages.
Houpu Li   +25 more
wiley   +1 more source

In vivo Terahertz Sensing of Skin Cancer Patients

open access: yesAdvanced Photonics Research, EarlyView.
This study presents the first in vivo measurements of skin cancer patients in a hospital setting using a handheld THz probe. Furthermore, a new analysis approach is developed to generate a patient‐normalized THz response function, which enables clear contrast to be seen between cancer and healthy skin of the same patient.The first in vivo study of skin
Jacob J. Young   +4 more
wiley   +1 more source

George Higoumenakis (1895-1983): Greek dermatologist [PDF]

open access: yes, 2009
This paper describes the Higoumenakis sign, enlargement of the sternal end of the clavicle in patients with late congenital syphilis and the dermatologist after whom it is named. Several professors and doctors from the Medical School of the University of
Frangos, CC, Frangos, CC
core   +1 more source

Microbiota‐Derived Inosine Suppresses Systemic Autoimmunity via Restriction of B Cell Differentiation and Migration

open access: yesAdvanced Science, EarlyView.
Lactobacillus johnsonii and its associated purine metabolite inosine not only restrict systemic B cell differentiation, but also contribute to immune cell infiltration in the kidneys, thereby serving dual functions in mitigating the progression of systemic lupus erythematosus (SLE).
Lingyu Gao   +15 more
wiley   +1 more source

Case of a 16‐Year‐Old Boy With Headache, Vomiting, and Behavioral Changes

open access: yes
Annals of Clinical and Translational Neurology, EarlyView.
Kundian Guo, Zhen Hong
wiley   +1 more source

Accurate Transcription Factor Activity Inference to Decipher Cell Identity from Single‐Cell Transcriptomic Data with MetaTF

open access: yesAdvanced Science, EarlyView.
MetaTF is a new computational framework that uses single‐cell RNA sequencing (scRNA‐seq) data to infer transcription factor activity with the aim to help in deciphering cells identity starting from a heterogeneous population, and apply it to characterize mouse hematopoietic stem cells and breast cancer epithelial cells, thus identifying a novel subset ...
Yongfei Hu   +15 more
wiley   +1 more source

Long-term safety and efficacy of trifarotene 50 μg/g cream, a first-in-class RAR-γ selective topical retinoid, in patients with moderate facial and truncal acne. [PDF]

open access: yes, 2020
BackgroundTreatment for both facial and truncal acne has not sufficiently been studied.ObjectivesTo evaluate the long-term safety and efficacy of trifarotene in both facial and truncal acne.MethodsIn a multicentre, open-label, 52-week study, patients ...
Ahmad, F   +11 more
core  

Low‐Irradiance Antimicrobial Blue Light‐Bathing Therapy for Wound Infection Control

open access: yesAdvanced Science, EarlyView.
Antimicrobial blue light has been shown as an appealing non‐pharmacological antimicrobial alternative. However, its clinical applications have been hindered by high irradiance‐associated photothermal risks. In this work, a low‐irradiance blue light‐bathing concept and a wearable photonic wound patch are established to address this challenge in terms of
Jie Hui   +12 more
wiley   +1 more source

Icaritin Represses Autophagy to Promote Colorectal Cancer Cell Apoptosis and Sensitized Low‐Temperature Photothermal Therapy via Targeting HSP90‐TXNDC9 Interactions

open access: yesAdvanced Science, EarlyView.
Icaritin demonstrates broad antitumor effects by inhibiting colorectal cancer (CRC) cell proliferation, migration, invasion, and causing cell cycle arrest. It induces apoptosis by repressing autophagic flux through disrupting HSP90‐TXNDC9 interactions.
Dan He   +6 more
wiley   +1 more source

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