Results 61 to 70 of about 275,152 (253)

The EXPLAIN Study: Exploring Arthrogryposis Multiplex Congenita in Adults in Norway — A Description of Demographic, Medical, and Neurological Findings

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Arthrogryposis Multiplex Congenita (AMC) encompasses several hundred conditions with diverse genetic, pathophysiological, and clinical origins. The overarching EXPLAIN study explores underlying causes and implications of AMC and represents the largest clinical cohort of adults with AMC reported to date.
My Vuong Hermansen, Kristin Ørstavik, Unni Steen, Mathias Toft, Cathrine Brunborg, Lena Lande Wekre   +5 more
wiley   +1 more source

A Case Report of a Rare Subacute Cutaneous Lupus Erythematosus with Chin Prostration

Clinical, Cosmetic and Investigational Dermatology
Wanni Li,1,2,* Wen Luo,1,* Yujia Liang,1,2 Ping Wang,1,2 Chunxia Wang,1,2 Jiejie Lu,1,2 Weiwei Wu1,2 1Department of Dermatology, Affiliated Dermatology Hospital of Hainan Medical University, Haikou, People’s Republic of China; 2Department
Li W, Luo W, Liang Y, Wang P, Wang C, Lu J, Wu W   +6 more
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Phenotypic profiling of pristane‐induced mimicking human systemic lupus erythematosus in Macaca fascicularis

Animal Models and Experimental Medicine, EarlyView.
Pristane (5 mL/kg) induced a robust systemic lupus erythematosus (SLE)‐like phenotype in Macaca fascicularis, marked by elevated antinuclear antibody (ANA) levels and systemic clinical, hematological, and biochemical changes. This model closely reflects human SLE and provides a translational platform for disease studies and therapeutic evaluation ...
Jonny Jonny, Soetojo Wirjopranoto, Chairul A. Nidom, I Ketut Sudiana, Terawan A. Putranto, Elisa D. Pratiwi, Tiza W. Mawaddah, Astria N. Nidom, Reviany V. Nidom, Setyarina Indrasari, Irma Y. Rosytania, Hiqmah Y. Yana, Sanindita Kusumastuti   +12 more
wiley   +1 more source

Safety and Efficacy of Hyaluronic Acid-Based Filler for Neck Wrinkles: A Prospective, Multicenter, Randomized, Parallel-Controlled Non-Inferiority Trial

Clinical, Cosmetic and Investigational Dermatology
Meng Jiang,1 Haiyan Cheng,1 Yan Li,1 Hongmei Ai,2 Jun Li,3 Yanjun Liang,4 Wei Xu1 1Department of Dermatology and Venereology, Beijing Friendship Hospital, Capital Medical University, Beijing, People’s Republic of China; 2Department of Plastic Surgery ...
Jiang M, Cheng H, Li Y, Ai H, Li J, Liang Y, Xu W   +6 more
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GS‐9620 alleviates psoriasis‐like inflammation by regulating autophagy in keratinocytes

Animal Models and Experimental Medicine, EarlyView.
Psoriasis is an immune‐mediated inflammatory disease of the skin characterized by excessive proliferation and abnormal differentiation of keratinocytes. GS‐9620 can increase the expression of ATG5, ATG7 and ATG16L1, thereby regulating the autophagy of keratinocytes and inhibiting the secretion of related inflammatory factors.
Yansi Lyu, Wei Zhou, Pei Zhang, Chen Lin, Xin Wen, Zigang Zhao, Guoqiang Zhang, Qian Zhang, Si Chen   +8 more
wiley   +1 more source

Evaluating Baricitinib for Severe Paediatric Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) with Single-Cell Sequencing

Journal of Inflammation Research
Danyang Yang,1 Xin Liu,1 Wenwen Jing,1 Xu Feng,1 Canying Lai,1 Chenyue Liu,2 Zhigang Xu,1,3 Yangang Zhang,1 Jiayi Han,1 Songmei Geng,1 Ruilian Li,1 Dan Li,4 Boyi Cheng,1 Yufei Wu,1 Zhuokun Liu,1 Jialin Lian,1 Zhenghui Wang,5 Yale Liu,1,* Xiaoli ...
Yang D, Liu X, Jing W, Feng X, Lai C, Liu C, Xu Z, Zhang Y, Han J, Geng S, Li R, Li D, Cheng B, Wu Y, Liu Z, Lian J, Wang Z, Liu Y, Li X   +18 more
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Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles

Advanced NanoBiomed Research, EarlyView.
This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley   +1 more source

Biological and Bioinspired Vesicles for Wound Healing: Insights, Advances and Challenges

International Journal of Nanomedicine
Yingchao Zhao,1,* Tingrui Zhang,1,* Guan Lin Zhao,2,* Jiaye Lu,1 Xinyue Zhang,1 Yongxian Lai,1 Zhongjian Chen,1 Xiaofeng Ding,1 Zongguang Tai1 1Shanghai Skin Disease Hospital, School of Medicine, Tongji University, Shanghai ...
Zhao Y, Zhang T, Zhao GL, Lu J, Zhang X, Lai Y, Chen Z, Ding X, Tai Z   +8 more
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Selenium Nanomaterials for Wound Healing: Synergistic Strategies from Anti‐Infection to Tissue Regeneration

Advanced NanoBiomed Research, EarlyView.
Selenium nanoparticles (SeNPs) are emerging as multifunctional platforms for wound healing, integrating antimicrobial, anti‐inflammatory, and proregenerative activities. This review summarises key mechanisms and recent advances in SeNP‐enabled composite dressings, immunomodulatory nanocomposites, microenvironment‐responsive hydrogels, photothermal and ...
Yangxia Chen, Xiaoshuang Liang, Sirui Li, Shuoshan Li, Wei Liu, Yingping Lin, Siqi Li, Zehang Zhang, Judun Zheng, Tianfeng Chen, Rongyi Chen   +10 more
wiley   +1 more source

Association of the Monocyte-to-High Density Lipoprotein Ratio with the FRS and as a Predictor of Cardiovascular Risk in Individuals with Psoriasis Vulgaris

Clinical, Cosmetic and Investigational Dermatology
Xueqin Gu,1,* Hongmei Shen,2,* Jiafeng Jiang,1,* Ping Gu,2,* Peilong Liu,2 Zhenguo Zhao,3 Jinfang Ge1 1Department of Dermatology, The Second People’s Hospital of Nantong, Nantong, Jiangsu Province, People’s Republic of ...
Gu X, Shen H, Jiang J, Gu P, Liu P, Zhao Z, Ge J   +6 more
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