Results 51 to 60 of about 316,264 (317)

Elemene Augments the Effects of Anti‐PD‐1 Immunotherapy on Hepatocellular Carcinoma by Regulating the miR‐130a‐5p/SPP/MHC‐I Axis

Advanced Science, EarlyView.
Elemene increases SPP expression by competitively binding with miR‐130a‐5p to suppress SPP mRNA degradation. This led to more antigen/MHC‐I complexes being expressed on the cell surface, which consequently facilitated the recognition and killing of HCC cells by CTLs and enhancing the antitumor immune efficacy of anti‐PD‐1.
Menglan Wang, Mengqing Sun, Heng Dong, Xiaoting Zhang, Jingbo Zhang, Zhengguo Zhang, Mengjie Ni, Lina Li, Yunxin Pei, Xiaoyu Chen, Qian Li, Fangtian Bu, Jiacheng Huang, Liangyu Jiang, Zhuting Fang, Xuliang Chen, Jianxiang Chen, Yiting Qiao, Tian Xie   +18 more
wiley   +1 more source

Predictors of Successful Secukinumab Dose Tapering in Moderate-to-Severe Psoriasis: A Retrospective Study

Psoriasis: Targets and Therapy
Jiawen Chen,1– 4,* Zhixun Xiao,1– 4,* Xueting Zeng,1– 4,* Niu Xiang,1– 4,* Renwei Luo,1– 4 Rongying Chen,1– 4 Beiqi Lin,1– 4 Hui Ke,1– 4 Ting Gong,5 Chao Ji1– 4 1Department of Dermatology, the First Affiliated Hospital of ...
Chen J, Xiao Z, Zeng X, Xiang N, Luo R, Chen R, Lin B, Ke H, Gong T, Ji C   +9 more
doaj  

Expert consensus on clinical treatment dilemmas in elderly patients with atopic dermatitis

Pifu-xingbing zhenliaoxue zazhi
Atopic dermatitis (AD) is a common chronic, recurrent, inflammatory skin disease. With the aging of the global population, the prevalence of atopic dermatitis is increasing in the elderly (>60 years old).
Dermatology Branch of Guangdong Elder Health Care Association
doaj   +1 more source

Rapid Arbitrary‐Shape Microscopy of Unsectioned Tissues for Precise Intraoperative Tumor Margin Assessment

Advanced Science, EarlyView.
This study presents a novel microscopic imaging system capable of rapid, section‐free scanning of irregular tissue surfaces, delivering high sensitivity for detecting cancer cell clusters during intraoperative tumor margin assessment. Abstract Rapid and accurate intraoperative examination of tumor margins is crucial for precise surgical treatment, yet ...
Zhicheng Shao, Xiangwei Meng, Peifen Fu, Keer Huang, Xibei Chen, Yue Ying, Jun Li, Yuxin Zheng, Xiaolong Li, Hyeon Jeong Lee, Jingyi Feng, Yuexin Lu, Runping Cai, Xiongling Jiang, Qing Chen, Hong Zhang, Xiaoyong Man, Li Lin   +17 more
wiley   +1 more source

The Saudi National Policy and Protocol for Epidermolysis Bullosa

Risk Management and Healthcare Policy
Ashjan Alheggi,1,* Amal Alhashem,2,3,* Hind Mohammad H Alshihry,4,* Sultan Al-khenaizan,5,* Fawwaz Freih Alshammrie,6,* Mariam M AlEissa,7– 10,* Hajer Y Almudaiheem,11,* Nancy Shehata,12,&ast ...
Alheggi A, Alhashem A, Alshihry HMH, Al-khenaizan S, Alshammrie FF, AlEissa MM, Almudaiheem HY, Shehata N, Alshingetti N, Almudeer AH, Alshammari IF, Alsefri MF, Al-jedai A, Eshmawi MT   +13 more
doaj  

DNA‐Inspired Multi‐Functional Double‐Cross‐Linking Self‐Healing Hydrogel Promotes the Healing of Diabetic Wounds

Advanced Science, EarlyView.
A self‐healing hydrogel crosslinked with dynamic nucleobase‐mimetic bonds delivers curcumin‐loaded exosomes. It promotes diabetic wound healing via a synergistic combination of antibacterial, anti‐inflammatory, pro‐angiogenic, and immunomodulatory mechanisms, providing a comprehensive therapeutic approach.
Pu Yang, Yue Hu, Yikun Ju, Naihsin Hsiung, Juyi Ye, Anquan Jian, Lanjie Lei, Bairong Fang   +7 more
wiley   +1 more source

A Case Report of Necrolytic Migratory Erythema Associated with Glucagonoma

Clinical, Cosmetic and Investigational Dermatology
Di Xia,* Zhouliang Liu,* Jiamin Li, Jingjing Liu, Yongbin Qu Dermatology Hospital of Southern Medical University, Southern Medical University, Guangzhou, People’s Republic of China*These authors contributed equally to this ...
Xia D, Liu Z, Li J, Liu J, Qu Y
doaj  

Images Made by Contagion: On Dermatological Wax Moulages

, 2022
Mechthild Fend
openalex   +1 more source

NIR‐Activatable Domino Cascade Catalysis Nanozyme Reactor for Multi‐Mechanism Synergistic Immunotherapy in Bladder Cancer

Advanced Science, EarlyView.
This study presents an intravesical delivery strategy of ferroptosis‐ and immunity‐inducing nanozyme‐loaded thermoresponsive hydrogels (FMCC@PNH) for enhanced bladder cancer therapy. Abstract Current intravesical therapies for bladder cancer after resection are limited by poor tissue penetration, off‐target effects, and insufficient efficacy.
Yongnan Jiang, Qingling Zhang, Yuhan Zhang, Xinlu Yu, Bo Jia, Yulong Dong, Yalong Wu, Kelong Fan, Xinquan Gu, Lei Ji, Wei Jiang, Bin Liu   +11 more
wiley   +1 more source

The Pendulum of Adherence: An Interpretative Phenomenological Analysis of Psoriasis Treatment Discontinuation

Patient Preference and Adherence
Zhanshuo Xiao,1,* Yilin Jiang,2,* Narina A Samah,2,* Heng Zhou,3 Junhui Wang1 1Department of Dermatology, Guanganmen Hospital, Beijing, 100053, People’s Republic of China; 2Faculty of Educational Sciences and Technology, Universiti Teknologi ...
Xiao Z, Jiang Y, Samah NA, Zhou H, Wang J   +4 more
doaj