Implementation of an Ultraviolet Phototherapy Service at a National Referral Hospital in Western Kenya: Reflections on Challenges and Lessons Learned. [PDF]
IntroductionIn order to manage skin conditions at a national referral hospital level in Kenya, specialized dermatology services, such as dermatologic surgery, dermatopathology, phototherapy, and sub-specialty care, should be offered, as is typically ...
Beck, Kristen+17 more
core
Collaborative Duality of CircGLIS3(2) RNA and Protein in human Wound Repair
CircGLIS3(2), a circRNA transiently upregulated in dermal fibroblasts during acute wound healing, is induced by IL‐1α and TGF‐β. Its RNA activates fibroblasts into matrix‐secreting cells, while its encoded protein enhances proliferation. The RNA stabilizes PCOLCE, and the protein interacts with BTF3, collectively accelerating wound repair. Abstract The
Guanglin Niu+20 more
wiley +1 more source
Identification of human papillomavirus DNA in cutaneous lesions of Cowden syndrome [PDF]
Background: Cowden syndrome (CS) or multiple hamartoma syndrome is a cancer-associated genodermatosis inherited in an autosomal dominant pattern. One of the diagnostic criteria is facial papules which are felt to be trichilemmomas, benign hair follicle ...
Burgdorf, Walter H. C.+4 more
core +1 more source
Structure and Antigenicity of Kaposi's Sarcoma‐Associated Herpesvirus Glycoprotein B
Kaposi's sarcoma‐associated herpesvirus (KSHV) causes severe cancers without effective treatments. This study presents an atomic model of KSHV's critical infection protein, gB, revealing a unique structure shared with related herpesviruses like Epstein‐Barr virus (EBV). The structural similarity highlights vulnerable targets for antibodies, guiding the
Xin‐Yan Fang+8 more
wiley +1 more source
Diabetic wound healing is blocked by persistent inflammation and oxidative stress. Bioactive substances like growth factors and Hsts promote repair but lack long‐term stability. Herein, a platelet membrane‐coated nanoparticle system (PNP) is proposed to achieve enhanced retention of aggregation‐induced emissive (AIE) molecular‐modified Hst1 (Hst1‐AIE ...
Xiaoxuan Lei+9 more
wiley +1 more source
Long-term follow-up of 22 psoriatic patients treated with ixekizumab after failure of secukinumab [PDF]
Switching of biologic agents in treatment of plaque psoriasis is a common strategy. Only a few studies are available on switching between IL17A-blockers.
Amschler, K+6 more
core +1 more source
Antioxidants in dermatology [PDF]
The skin cells continuously produce, through cellular respiration, metabolic processes or under external aggressions, highly reactive molecules oxidation products, generally called free radicals. These molecules are immediately neutralized by enzymatic and non-enzymatic systems in a physiological and dynamic balance. In situations where this balance is
openaire +5 more sources
Smart Transfemoral Prosthetic Socket with Motorized Cable‐Driven System
This study presents an innovative transfemoral socket featuring a motorized cable‐driven system and a sensorized liner, designed to adapt to changes in residual limb volume while monitoring interface pressures. Users can seamlessly control the socket in both open‐ and closed‐loop modes via a customized mobile application, enhancing comfort and ...
Linda Paternò+7 more
wiley +1 more source
Research in Cosmetic Dermatology: Reconciling medicine with business [PDF]
Cosmetic dermatology is a marriage between medicine and business. Research in cosmetic dermatology shares the fundamental principles of clinical and pharmaceutical research.
Eapen, Bell R
core +1 more source
Challenges to smartphone applications for melanoma detection [PDF]
This commentary addresses the emerging market for health-related smartphone applications. Specific to dermatology, there has been a significant increase not only in applications that promote skin cancer awareness and education but also in those meant for
Chapman, Lance W.+2 more
core +1 more source