Results 91 to 100 of about 16,089,508 (287)

The psychosocial impact of acne vulgaris

Indian Journal of Dermatology, 2016
Background: Acne vulgaris causes erythematous papulopustular lesions in active stage and often leave behind residual scarring and pigmentation. Its onset in adolescence may add to the emotional and psychological challenges experienced during this period.
Neirita Hazarika, M Archana
doaj   +1 more source

A Hepatocyte‐to‐Stellate Cell Axis Couples Alternate‐Day Fasting to Liver Fibrosis Resolution via ATG7 S‐Nitrosylation

Advanced Science, EarlyView.
Alternate‐day fasting suppresses mitochondrial complex II assembly via SDHAF4 to upregulate hepatocyte eNOS. The resulting nitric oxide S‐nitrosylates ATG7 at C184 in hepatic stellate cells, restraining autophagic flux and preventing their profibrotic activation.
Xueqiang Wang, Mengqi Zeng, Cunxiao Sun, Yuhan Gou, Zhaode Feng, Weiqiang Lv, Chaoying Yan, Hansen Wu, Pengfei Zhang, Jie Xu, Ke Cao, Hao Li, Mingge Ding, Zhongbo Liu, Xing Zhang, Jiankang Liu, Xuan Zou, Zhihui Feng   +17 more
wiley   +1 more source

Dermatology Life Quality Index: Data from Danish Inpatients and Outpatients

Acta Dermato-Venereologica, 2000
The aim of the present study was to provide data on the reliability and validity of a Danish translation of the Dermatology Life Quality Index (DLQI), a short measure of the impact of dermatological diseases on quality of life. The DLQI was administered to 200 outpatients and 100 hospitalized patients suffering from a range of dermatological diseases ...
Zachariae, R; id_orcid 0000-0001-9076-3068, Zachariae, C, Ibsen, H, Mortensen, J T, Wulf, H C   +4 more
openaire   +4 more sources

Low‐Intensity Ultrasound‐Triggered Microbubble Cavitation Attenuates Diabetic Kidney Injury Partially by Reversing Endothelial Dysfunction

Advanced Science, EarlyView.
Non‐invasive low‐intensity pulsed ultrasound ‐triggered cavitation of clinically approved diagnostic‐grade microbubbles delivers favorable mechanical stimuli to renal microvasculature. This intervention restores renal microvascular homeostasis, alleviates DKD‐associated histological and functional damage, and suppresses inflammatory and fibrotic ...
Yubo Lai, Liang Zhang, Wenxin Tao, Jieyuan An, Lantian Wang, Zhaoyou Liu, Guodong Yang, Pengying Wu, Lijun Yuan   +8 more
wiley   +1 more source

Long‐Term Human Skin Platform for Modeling Chronic Inflammation, Environmental Stress, and Therapeutic Intervention

Advanced Science, EarlyView.
An advanced, long‐term human skin platform maintains native skin structure and key tissue functions for up to four weeks. The platform models chronic inflammation, aging‐related skin changes, and UVB damage, enabling drug and topical interventions—including anti‐inflammatory therapy, senolytic treatment, and sunscreen—to be evaluated in intact human ...
Purnendu Kumar Sharma, Evelien Schaafsma, Elysia Anderson, Jocelyn Chiari, Paige Thompson, Erin Galt, Sunghoon Lee, Jason Holsapple, Sai Hein, Bailey L. Coates, Jade Michaud, Sabrina Zuccaro, Lia Kent, Chris Hinojosa, Kyung‐Jin Jang   +14 more
wiley   +1 more source

Efficacy of intralesional tranexamic acid in melasma: Assessment with Melasma Area Severity Index and Dermatology Quality of Life Index

, 2022
Background and Design: Melasma is a common hypermelanotic condition, mostly observed in women, which affects their psychological, emotional, and social well-being as well as their quality of life.
Ashna Ashraf, Rajashekar T. S., Sneha Krishnoji Rao   +2 more
core   +1 more source

Lipid Metabolic Dysregulation Driven by OSMR Mutations Underlies Amyloidogenesis in Primary Localized Cutaneous Amyloidosis

Advanced Science, EarlyView.
OSMR mutations disrupt STAT5 signaling and AKR1B10‐mediated lipid metabolism, leading to lipid accumulation and protein aggregation in keratinocytes. This metabolic reprogramming drives amyloid deposition in primary localized cutaneous amyloidosis, revealing a mechanistic link between lipid dysregulation and amyloidogenesis.
Huiting Liu, Wen Zheng, Chao Yang, Tao Yang, Qiuyu Chen, Ping Lu, Huan Yang, Jun Liu, Bin Yang   +8 more
wiley   +1 more source

Life Quality Assessment among Adult Patients with Atopic Dermatitis

, 2007
Background: Quantification of quality of life (QOL) related to disease severity is important in patients with atopic dermatitis (AD), because the assessment provides additional information to the traditional objective clinical scoring systems. Objective:
이주희, 이광훈
core  

Correlation between Psoriasis Area Severity Index and Dermatology Life Quality Index in Patients of Psoriasis: A Cross-Sectional Study

Nepal Journal of Dermatology, Venereology & Leprology
Introduction:Psoriasis is a chronic skin disease that affects both the physical and social aspects of a patient’s life. The disease's severity, as measured by the Psoriasis Area Severity Index (PASI), can significantly impact the patient’s quality of ...
S Drishya, Deepadarshan Kalegowda, Shashikumar Basavapura Madegowda, Phani Halevoor   +3 more
doaj   +3 more sources

Anxiety, Depression and Dermatology Life Quality Index Scores in Dermatology Outpatients

Clinical Dermatology Open Access Journal
Background: The physical or perceived disfigurement can become a source of significant distress, with a considerable impact on an individual’s psychological, social, and physical well-being. Dermatological conditions are responsible for a significant source of social stigmatization in many human societies and cultures, contributing to the development ...
Najat H Belkhair, Ghada A Albarghathi*, Gamal A Duweb   +2 more
openaire   +1 more source