Results 101 to 110 of about 16,089,508 (287)

An Adenoviral‐Vectored Tp0326 Vaccine Elicits Robust Functional Antibodies to Prevent Treponema pallidum Dissemination in a Rabbit Model

Advanced Science, EarlyView.
Vaccination promotes cellular infiltration into primary lesions and effectively inhibits T. pallidum dissemination to distal organs. Notably, transfer of lesion tissue from immunized animals fails to establish infection in naive recipients, confirming specific protective immunity.
Yinbo Jiang, Xinyuan Li, Lixia Huang, Xiangcai Zhang, Wujian Ke   +4 more
wiley   +1 more source

Quality Of Life in Patients with Non-Genital Warts: A Cross-Sectional Study using Dermatology Life Quality Index (DLQI) Questionnaire [PDF]

, 2022
Introduction: Warts are one of the commonest causes for the dermatology outpatient department visits. These are caused by the Human Papilloma Viruses (HPV). Sometime warts can cause significant embarrassment and consequently impair the quality of life.
Indu Acharya, Sushil Paudel, Prajwal Pudasaini, Monique Kafle   +3 more
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Targeting Macrophage STING O‐GlcNAcylation via Small‐Molecule Allosteric Modulation for Psoriasis Therapy

Advanced Science, EarlyView.
Paeoniflorin allosterically targets the STING cyclic dinucleotide‐binding domain, stabilizes an inactive open conformation, and disrupts STING–OGT interaction to reduce Thr229 O‐GlcNAcylation and downstream signaling. This mechanism restrains myeloid STING activation, alleviates psoriasis‐like inflammation, and is supported by analyses of patient ...
Fang‐Fang Zhuo, Cheng‐Chen Hou, Wei Wang, Ya‐Xuan Zhu, Ling Li, Li‐Juan Liu, Chuan‐Jian Lu, Peng‐Fei Tu, Yang Liu, Rui‐Zhi Zhao, Ke‐Wu Zeng   +10 more
wiley   +1 more source

Quality of life measurement in hidradenitis suppurativa:position statement of the European Academy of Dermatology and Venereology task forces on Quality of Life and Patient-Oriented Outcomes and Acne, Rosacea and Hidradenitis Suppurativa

, 2019
This paper is organized jointly by the European Academy of Dermatology and Venereology (EADV) Task Force (TF) on Quality of Life (QoL) and Patient-Oriented Outcomes and the EADV TF on acne, rosacea and hidradenitis suppurativa (ARHS). The purpose of this
L. Tomas‐Aragones, Manolache, L, Pustisek, N., G.B. Jemec, S.E. Marron, Abeni, D, C.C. Zouboulis, L. Manolache, T. Tzellos, A. Bewley, Linder, D., M. Augustin, S. Spillekom‐van Koulil, van der Zee, H. H., Abeni, D., Szepietowski, J. C., Manolache, L., Svensson, A., Tomas-Aragones, L., Bewley, A, Szepietowski, JC, Jemec, G. B., J.C. Szepietowski, Spillekom-van Koulil, S., Augustin, M, Pustisek, N, Augustin, M., N. Pustisek, D. Abeni, Sampogna, F, Marron, SE, Finlay, AY, Tomas-Aragones, L, P.V. Chernyshov, Tzellos, T., van der Zee, Hessel, A.Y. Finlay, A. Svensson, Chernyshov, P. V., Linder, D, Tzellos, T, Zouboulis, C. C., Finlay, A. Y., D. Linder, Marron, S. E., Sampogna, F., Spillekom-van Koulil, S, H.H. van der Zee, Zouboulis, CC, F. Sampogna, Chernyshov, PV, Svensson, A, Jemec, G B, Bewley, A.   +53 more
core   +1 more source

Targeting Cannabinoid 1 Receptor in Macrophages Alleviates Psoriatic Skin Inflammation Through the AUF1–NLRP3 Axis

Advanced Science, EarlyView.
Macrophage CB1R emerges as a key driver of psoriatic inflammation by suppressing AUF1‐mediated post‐transcriptional control of NLRP3. CB1R inhibition restores AUF1‐dependent NLRP3 mRNA decay, restrains inflammasome activation, and alleviates psoriasis‐like inflammation.
Hongseo Choi, Sukyoung Han, Jinho Kim, Ji Hye Han, Eunsu Kim, Yeonjeong Heo, Minju Lee, Jooyoung Lee, Heerim You, Soyoun Lee, Su‐Hee Han, Ilrok Yoon, Sung Anjeon, Hyerim Kang, Seungyeon Ryu, Hyun‐Ji Park, Eunha Kim, Chul Hwan Bang, Ji Hyun Lee, Josephine M. Egan, Jung‐Woong Kim, Eun Kyung Lee, Wook Kim   +22 more
wiley   +1 more source

Comparing the Quality of Life of Patients and their Family Members with Dermatological and other Chronic Conditions, in The Bahamas

Caribbean Medical Journal, 2023
Background & Objectives: Impact of dermatological and other chronic conditions not only affects the quality of life (QoL) of patients but also that of their family members.
Chanta’l Clare-Kleinbussink, Flora Kiss, Morton A.C. Frankson, Andrew Y. Finlay, Jui Vyas   +4 more
doaj  

Symptom‐Driven Prediction of Chronic Multimorbidity with a Macro–Micro Heterogeneous Graph Neural Network

Advanced Science, EarlyView.
Clinical symptoms offer a window into multimorbidity. A macro‐micro heterogeneous graph neural network integrates clinical records with biomedical knowledge to improve patient‐level symptom‐disease association learning and visit‐level multimorbidity completion.
Yiheng Ye, Miaoru Han, Siqiao Tang, Zongxiang Zhang, Haichen Shen, Bingzhen Sun, Yan Zhang, Xiaodong Chu, Lijuan Deng, Chaoyang Zheng, Qingchun Huang, Kun Bao, Ronghua Zhang, Yong Wang, Fengwei Zhang, Xiaoli Chu   +15 more
wiley   +1 more source

Quimp (QUality of life IMPairment): an addition to the Quality of Life lexicon

, 2017
There has been a constant growth in the number of publications each year concerning "quality of life (QoL)" and "dermatology," since the publication of the Dermatology Life Quality Index in 1994.
Augustin, M., Szepietowski, J C, L. Tomas-Aragones, O.D. van Cranenburgh, Sampogna, F, Linder, M D, Manolache, L, M.D. Linder, van Cranenburgh, O D, Linder, M. D., Pustišek, N, Tomas-Aragones, L, P.V. Chernyshov, Chernyshov, P V, Salek, M S, A. Svensson, Chernyshov, P. V., G.B. Jemec, S.E. Marron, L. Manolache, A. Bewley, M.S. Salek, N. Pustišek, M. Augustin, F. Poot, Poot, F, Marron, S. E., Sampogna, F., Szepietowski, J. C., Manolache, L., Svensson, A., Tomas-Aragones, L., van Cranenburgh, O. D., Salek, N. N., Marron, S E, F. Sampogna, Poot, F., Bewley, A, Pustišek, N., Jemec, G. B., J.C. Szepietowski, Svensson, A, Augustin, M, Jemec, G B, Bewley, A.   +44 more
core   +1 more source

Autonomous AI‐Driven Design for Skin Product Formulations

Advanced Intelligent Discovery, EarlyView.
This review presents a comprehensive closed‐loop framework for autonomous skin product formulation design. By integrating artificial intelligence‐driven experiment selection with automated multi‐tiered assays, the approach shifts development from trial‐and‐error to intelligent optimisation.
Yu Zhang, Yongrui Xiao, Chunlin Chen, Dimitrios Tsaoulidis, Kai Yang, Tao Chen   +5 more
wiley   +1 more source

Carcinoma basocelular: estimativa da qualidade de vida, infiltrado inflamatório e avaliação das margens laterais após exérese por bisturi de lâmina dupla [PDF]

, 2013
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Ciências Médicas, Florianópolis, 2013.Introdução: O carcinoma basocelular (CBC) é o tumor maligno de pele mais comum em humanos ...
Nunes, Daniel Holthausen.
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