Results 121 to 130 of about 70,002 (313)

Introduction of a novel magnetic resonance imaging-based scoring system for assessing disease activity in children with juvenile dermatomyositis [PDF]

, 2018
Objectives: We aimed to develop and assess the reliability of a novel MRI-based scoring system for reporting the severity of MRI findings in children with suspected JDM.
Adams, Amaka C Offiah, Bohan, Bohan, Brown, Caren Landes, Clarissa Pilkington, Davis, Feldman, Gowdie, Hernandez, Hernandez, Jeannette Kraft, Karl Johnson, Kaufman, Kimball, Love, Lundberg, Maillard, Malattia, Mandela Thyoka, McCann, Oba Adekunle, Owen J Arthurs, Park, Paul Humphries, Pitt, Raj Sinha, Robinson, Stephen Walters, Symmons, Tanimoto, Targoff, Thara Persaud, Van Ness, Walter, Weber   +36 more
core   +2 more sources

Epidemiology and Genetics of Rheumatic Diseases Suggest a Constant Rate of DNA Damage as Underlying Cause

Immunology, EarlyView.
A constant rate of DNA damage that is not perfectly repaired will cause a constant rate of DNA mutations. The chance of mutation will increase if DNA is prone to damage, such as occurs in somatic hypermutation (SHM) hotspots and GC‐rich DNA. Thus, if one mutation‐prone DNA site drives disease, the age of onset of disease and degree of penetrance should
Piet C. de Groen
wiley   +1 more source

Comparison of the Utility and Validity of Three Scoring Tools to Measure Skin Involvement in Patients With Juvenile Dermatomyositis [PDF]

, 2016
OBJECTIVE: To compare the abbreviated Cutaneous Assessment Tool (CAT), Disease Activity Score (DAS), and Myositis Intention to Treat Activity Index (MITAX) and correlate them with the physician's 10-cm skin visual analog scale (VAS) in order to define ...
Almeida, B, Arnold, K, Campanilho-Marques, R, de Iorio, M, Deakin, C, Gallot, N, Juvenile Dermatomyositis Research Group, ., Nistala, K, Pilkington, CA, Wedderburn, LR   +9 more
core   +1 more source

Possible involvement of keratinocyte‐derived microvesicle particles in human photosensitivity disorders

Photochemistry and Photobiology, EarlyView.
In this model, ROS generated by UVB result in PAFR agonists acting upon the PAFR resulting in MVP generation release via the enzyme aSMase. In photosensitivity, there are increased ROS, resulting in augmented PAF agonists and increased MVP release. This process can be blocked by aSMase inhibitors.
Risha Annamraju, Madison S. Owens, Anita Thyagarajan, Danielle A. Corbin, Catherine M. T. Sherwin, Jade Bryant, Garrett W. Fisher, Winston R. Owens, Alycia Ketter, Aadil Umerani, Craig A. Rohan, Michael G. Kemp, Robyn K. Crow, Jeffrey B. Travers   +13 more
wiley   +1 more source

Inflammatory Myopathies with Cutaneous Involvement: from Diagnosis to Therapy

Folia Medica, 2017
The group of idiopathic inflammatory myopathies (IIM) include various disorders of skeletal muscles with or without skin involvement. The most common types are dermatomyositis (DM), polymyositis (PM), inclusion body myositis (IBM) and necrotizing ...
Dourmishev Lyubomir A.
doaj   +1 more source

Clinical Characteristics and Management of Patients With Clinical Amyopathic Dermatomyositis: A Retrospective Study of 64 Patients at a Tertiary Dermatology Department

, 2021
Keyun Tang, Hanlin Zhang, Hongzhong Jin
openalex   +1 more source

Anti‐Melanoma Differentiation‐Associated Gene 5 Antibody‐Positive Interstitial Lung Disease, Induced by Enfortumab Vedotin Plus Pembrolizumab for Advanced Urothelial Carcinoma

IJU Case Reports, Volume 9, Issue 2, March 2026.
ABSTRACT Introduction Anti‐melanoma differentiation‐associated gene 5 antibody‐positive interstitial lung disease is a rare but fatal adverse event following immune checkpoint inhibitor treatment for cancers. However, such cases have not been previously reported in patients with urothelial carcinoma.
Akira Saito, Hiroki Ishihara, Hanae Kondo, Toshio Takagi, Yasunobu Hashimoto   +4 more
wiley   +1 more source

Fulminant systemic capillary leak syndrome due to C1 inhibitor deficiency complicating acute dermatomyositis: a case report [PDF]

, 2014
INTRODUCTION: Dermatomyositis is a chronic inflammatory disorder characterized by muscular and dermatologic symptoms with variable internal organ involvement.
Andreas Brunauer, Daniel Neureiter, Hermann Salmhofer, Ilse Gradwohl-Matis, Martin W Dünser, Romana Illig   +5 more
core   +1 more source

Dermatomyositis presenting with symptomatic dermographism and raised troponin T: a case report

Journal of Medical Case Reports, 2009
Introduction Dermatomyositis is an important inflammation of skin and muscles. Generalised itch is frequent in the condition; however, symptomatic dermographism has not previously been reported as a presenting feature.
Rahim Kartini F, Dawe Robert S
doaj   +1 more source

Cyclophosphamide-induced liver injury during treatment of interstitial lung disease in juvenile dermatomyositis [PDF]

, 2023
Yue Zhang, Christopher Costin
openalex   +1 more source