Results 181 to 190 of about 35,808 (310)
TNF Inhibitor Therapy in Corticosteroid‐Resistant or ‐Dependent Pediatric Neutrophilic Dermatosis
ABSTRACT Neutrophilic dermatoses are rare in children. Systemic corticosteroids are the first‐line treatment, but guidelines for second‐line therapies are lacking. We report five cases of children with systemic steroid‐resistant/dependent neutrophilic dermatoses, successfully treated with tumor necrosis factor inhibitors.
Laure Chêne +7 more
wiley +1 more source
Male external genital skin disorders: a retrospective analysis from a tertiary hospital in China. [PDF]
Qian YT +5 more
europepmc +1 more source
Journal of the European Academy of Dermatology and Venereology, EarlyView.
S. Benkimoun +14 more
wiley +1 more source
Prescribing Patterns in Pediatric Hidradenitis Suppurativa
ABSTRACT Hidradenitis suppurativa (HS) is an inflammatory skin condition increasingly diagnosed in pediatric populations; however, data on treatment practices in this group remains limited. In this retrospective study of 163 patients diagnosed with HS ≤ 18 years of age, we found that treatment patterns varied significantly by disease severity.
Hannah Neimy +3 more
wiley +1 more source
Canine atopic dermatitis (cAD) is a chronic condition requiring life‐long management. Accurate diagnosis can be challenging, with no reliable diagnostic test. This study aimed to generate a simple diagnostic model for cAD. This model is a relevant prototype for an app‐based tool to support general practitioners in the diagnosis of cAD alongside ...
Xavier Langon +2 more
wiley +1 more source
Discovery of a First‐in‐Class Covalent Allosteric SHP1 Inhibitor with Immunotherapeutic Activity
A covalent allosteric inhibitor M029 was discovered for SHP1, a novel target for immunotherapy. M029 binds to a cryptic Cys remote from the active site, exhibits robust target engagement, and blocks tumor progression by stimulating antitumor immune response.
Zihan Qu +16 more
wiley +2 more sources
Off-label use of abrocitinib in dermatology: A systematic literature review with narrative summary. [PDF]
Su Z, Sun C, Yao WH, Wang P, Zeng YP.
europepmc +1 more source
Congenital Hypotrichosis in a female Rottweiler [PDF]
Ihrke, P. J. +2 more
core +1 more source
Treatment of Reactive Histiocytosis With Oclacitinib: A Retrospective Case Series of 10 Dogs
Background: Canine reactive histiocytosis is a proliferative disorder of activated interstitial dendritic cells with cutaneous and systemic forms. An immune‐mediated aetiology is likely, and systemic immunomodulatory agents such as corticosteroids, tetracycline/niacinamide, ciclosporin, azathioprine and leflunomide have been employed for its management.
Christine L. Cain +2 more
wiley +1 more source

