Results 1 to 10 of about 25,736 (119)

Pathogenic role of S100 proteins in psoriasis

Frontiers in Immunology, 2023
Psoriasis is a chronic inflammatory skin disease. The histopathological features of psoriasis include excessive proliferation of keratinocytes and infiltration of immune cells.
Huifang Liang, Huifang Liang, Junqin Li, Junqin Li, Kaiming Zhang, Kaiming Zhang   +5 more
doaj   +1 more source

Dermatoses in the elderly: Clinico-demographic profile of patients attending a tertiary care centre

Indian Journal of Dermatology, 2021
Background: Elderly population is vulnerable to develop a multitude of dermatological diseases, owing to comorbidities and polypharmacies. Objective: To know the prevalence of dermatological conditions in elderly patients attending outpatient department,
Dhiraj Kumar, Anupam Das, Debabrata Bandyopadhyay, Satyendra N Chowdhury, Nilay K Das, Preeti Sharma, Amit Kumar   +6 more
doaj   +1 more source

Dermal mesenchymal stem cells: a resource of migration-associated function in psoriasis?

Stem Cell Research & Therapy, 2019
Background Psoriasis is a chronic and systemic, immune-mediated, inflammatory disease. Mesenchymal stem cells have effects on the inflammatory microenvironment, including regulating the proliferation, differentiation, recruitment, and migration of ...
Xuping Niu, Junqing Li, Xincheng Zhao, Qiang Wang, Gang Wang, Ruixia Hou, Xinhua Li, Peng An, Guohua Yin, Kaiming Zhang   +9 more
doaj   +1 more source

Variation at ACOT12 and CT62 locus represents susceptibility to psoriasis in Han population

Molecular Genetics & Genomic Medicine, 2020
Background Psoriasis is a chronic inflammatory disorder of the skin, and genetic factors are reported to be involved in the disease pathogenesis. Many studies have named psoriasis candidate genes.
Jianxiao Xing, Xincheng Zhao, Xiaofang Li, Ying Wang, Junqin Li, Ruixia Hou, Xuping Niu, Guohua Yin, Xinhua Li, Kaiming Zhang   +9 more
doaj   +1 more source

The role of actin cytoskeleton component Arp2/3 in inflammatory response

Frontiers in Cell and Developmental Biology
Actin regulatory protein plays an important role in immune-related diseases and affects cellular behavior by regulating the dynamic changes of the cytoskeleton.
Jianxiao Xing, Ying Wang, Yanyang Liang, Jiao Li, Yuanjun Yao, Junqin Li, Kaiming Zhang   +6 more
doaj   +1 more source

Possible relationship between poor skin disorders prognosis and serum zinc level: A narrative review

Dermatology Reports, 2022
Zinc is a trace nutrient essential for the normal growth and development of human body. The main aim was to evaluate the significant association between measured zinc status in relation to different skin disorders and their severity.
Mohammed Abadie, Zinah Sharara, Miriam Abadie, Patrick Ball, Hana Morrissey   +4 more
doaj   +1 more source

The function of phosphoglycerate mutase 1 (PGAM1) and its role in diseases

Frontiers in Molecular Biosciences
Phosphoglycerate mutase 1 (PGAM1) is a pivotal metabolic enzyme during the process of glycolysis, catalyzing the interconversion between 3-phosphoglycerate and 2-phosphoglycerate.
Aihong Peng, Junqin Li, Huifang Liang, Yuanjun Yao, Kaiming Zhang   +4 more
doaj   +1 more source

Clarithromycin-based therapy with adjunctive photobiomodulation and microwave treatment for cutaneous Mycobacterium marinum infection

Photodiagnosis and Photodynamic Therapy
Background: Cutaneous Mycobacterium marinum (M. marinum) infection poses substantial diagnostic and therapeutic challenges and often necessitates prolonged multidrug antibiotic regimens, which are frequently associated with poor adherence and potential ...
Yaru Su, Wen Zhao, Yueqiong Yang, Miao Hong, Yinghua Zhu   +4 more
doaj   +1 more source

ADIPOQ regulates lipid metabolism by activating AMPK/CPT-1 pathway to attenuate the proliferation of psoriasis lesions

Scientific Reports
Psoriasis is an immune-mediated chronic inflammatory skin disease, with over 100 million people affected worldwide. This disease is accompanied by significant lipid metabolism disorders, affecting the circulatory system and skin tissue.
Jianxiao Xing, Jiao Li, Aihong Peng, Ying Wang, Yuanjun Yao, Yali He, Junqin Li, Kaiming Zhang   +7 more
doaj   +1 more source

Case Report: Upadacitinib and apremilast combination therapy for guselkumab-induced paradoxical eczema in psoriasis

Frontiers in Immunology
Psoriasis is an immune-mediated inflammatory skin disease. Although biologics have markedly improved psoriasis symptoms, they may occasionally trigger paradoxical inflammatory reactions, particularly with IL-17A or TNF-α inhibitors.
Luan Yang, Jing Zhou, Zhenqiang Ruan, Keshi Shi   +3 more
doaj   +1 more source