Results 31 to 40 of about 36,760 (309)

Successful Co‐Administration of Secukinumab and Dupilumab in a Patient With Psoriasis and Paradoxical Atopic Dermatitis

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Paradoxical atopic dermatitis (AD) can arise during biologic therapy for psoriasis due to an immune‐axis imbalance. We describe a 47‐year‐old man who developed severe AD while receiving secukinumab, which was successfully managed with the addition of dupilumab, allowing long‐term control of both diseases.
So Yun Park   +6 more
wiley   +1 more source

Crotonylation deficiency of S100A7 K49 promotes psoriatic keratinocyte proliferation through enhanced interaction with RAGE

open access: yesScientific Reports
Psoriasis is a chronic inflammatory dermatosis characterized by the hyperproliferative of keratinocytes. S100A7 plays a pivotal role in the pathogenesis of psoriasis.
Huifang Liang   +3 more
doaj   +1 more source

Apremilast in the treatment of pityriasis lichenoides et varioliformis acuta: a case report

open access: yesJournal of Dermatological Treatment
Objectives To evaluate the efficacy and safety of apremilast, a phosphodiesterase-4 (PDE-4) inhibitor, in treating pityriasis lichenoides et varioliformis acuta (PLEVA) and explore its potential mechanisms.Methods We present a 16-year-old male with ...
Jing Zhou   +5 more
doaj   +1 more source

Acantholytic dermatosis of the vulva [PDF]

open access: yesDermatology Online Journal, 2015
Acantholytic dermatosis of the vulva is a rare condition, presenting with papular eruption in the genital area without history of Darier disease or Hailey-Hailey disease. We report a case with a papular pruritic eruption in the region of the vulva, coalescing into plaques.
Mansura, Adva   +3 more
openaire   +4 more sources

Refractory Eczema as a Presenting Feature of Common Variable Immunodeficiency

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Common variable immunodeficiency (CVID) is the most prevalent symptomatic inborn error of immunity (IEI) in adults. It presents with recurrent infections and non‐infectious complications, including autoimmunity, lymphoproliferation and dermatitis.
Mercedes Sanchez‐Diaz   +2 more
wiley   +1 more source

Leporacarus gibbus (Acari: listrophoridae) in a naturally-infested domestic rabbit: first report of its occurrence in the state of Espírito Santo, Brazil

open access: yesBioscience Journal, 2018
This study aimed to report the first occurrence of Leporacarus gibbus in a domestic rabbit (Oryctolagus cuniculus) from the state of Espírito Santo, Brazil.
Leonardo Lima Gorza   +8 more
doaj   +3 more sources

Regulation of epidermal barrier function and pathogenesis of psoriasis by serine protease inhibitors

open access: yesFrontiers in Immunology
Serine protease inhibitors (Serpins) are a protein superfamily of protease inhibitors that are thought to play a role in the regulation of inflammation, immunity, tumorigenesis, coagulation, blood pressure and cancer metastasis.
Juanjuan Wang   +9 more
doaj   +1 more source

Regulatory role of transcription factor c-Myc in the pathogenesis of psoriasis [PDF]

open access: yesPeerJ
Psoriasis is a chronic relapsing dermatosis characterized by hyperproliferation and poor differentiation of keratinocytes (KCs). The c-Myc gene is one of the main members of the Myc family and exerts multiple biological functions.
Yue Cao, Xu-Ping Niu, Kai-Ming Zhang
doaj   +2 more sources

ASHY DERMATOSIS - TRATAMENTO COM CLOFAZIMINA [PDF]

open access: yes, 2013
Ashy dermatosis, or erythema dyschromicum perstans, is a rare dermatosis of unknown etiology. The au- thors report the case of a 46-year-old healthy man that presented with a 1-year history of asymptomatic gray macules on the trunk.
Selores, Manuela   +7 more
core   +1 more source

Chronic Hand Eczema of Charlie Chaplin

open access: yesJEADV Clinical Practice, EarlyView.
Abstract Charlie Chaplin (1889–1977), one of the most iconic figures in cinema history, suffered throughout his career from a chronic hand eczema he consistently concealed behind white cotton gloves. According to his biographers, Chaplin attributed this condition to the prolonged handling of cellulose nitrate film stock during editing—a highly ...
Bruno Halioua, Charles Taieb
wiley   +1 more source

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