Results 51 to 60 of about 24,027 (216)
Drug reactions with skin manifestations. How to discover?
Лечащий Врач, 2021 Reasons of appearance and clinical manifestations of toxicodermia were considered. It was indicated that drug reactions with skin manifestations are extremely versatile.
Yu. G. Haliulin, D. Sh. Macharadze
doaj +2 more sources
Screening of key genes related to disulfidptosis in psoriasis based on the analysis of WGCNA
Scientific ReportsPsoriasis features keratinocyte hyperproliferation. This study aimed to identify disulfidptosis-related key genes in psoriasis for potential diagnostic biomarkers or therapeutic targets.
Qingshan Li +4 more
doaj +1 more source
Oral tofacitinib for generalized Dowling-Degos disease with refractory pruritus: a case report
Journal of Dermatological TreatmentAim To evaluate the efficacy and safety of the Janus kinase (JAK) inhibitor tofacitinib in generalized Dowling-Degos disease (DDD) with refractory pruritus and to comparatively analyze its advantages and limitations versus existing therapies.Methods We ...
Luan Yang +5 more
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Refractory Eczema as a Presenting Feature of Common Variable Immunodeficiency
JEADV Clinical Practice, EarlyView.ABSTRACT Common variable immunodeficiency (CVID) is the most prevalent symptomatic inborn error of immunity (IEI) in adults. It presents with recurrent infections and non‐infectious complications, including autoimmunity, lymphoproliferation and dermatitis.
Mercedes Sanchez‐Diaz +2 more
wiley +1 more source
The role of SPRED1 mutation in melanoma
European Journal of Medical ResearchMelanoma is a highly malignant tumor, with its initiation and progression tightly linked to the aberrant activation of the MAPK signaling pathway. As a critical negative regulator of the MAPK pathway, SPRED1 frequently exhibits genomic alteration in ...
Hui Hou +3 more
doaj +1 more source
Practice Patterns in Extramammary Paget's Disease
JEADV Clinical Practice, EarlyView.ABSTRACT Background In patients with Extramammary Paget's Disease (EMPD), a rare intraepithelial adenocarcinoma, wide local excision (WLE) has historically been the standard of treatment despite high rates of positive margins and recurrence. Mohs micrographic surgery (MMS) has demonstrated superior outcomes, yet practice patterns vary due to limited ...
Yasmine Mohseni +4 more
wiley +1 more source
The regulatory mechanisms and treatment of HDAC6 in immune dysregulation diseases
Frontiers in ImmunologyHistone deacetylase 6 (HDAC6) is a class IIb histone deacetylase that contains two catalytic domains and a zinc finger ubiquitin binding domain (ZnF-UBP). The deacetylation function of HDAC6 has been extensively studied with well-characterized substrates
Yanyang Liang +9 more
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Characteristics of Sensitive Scalp in French Women and Comparison With Scalp Dermatoses
JEADV Clinical Practice, EarlyView.ABSTRACT Background A sensitive scalp is a particular location of sensitive skin, characterised by the occurrence of unpleasant sensations which cannot be explained by a skin disease. It is a common syndrome that could affect 30%–50% of women. Clinical data are scarce, and the impact on the quality of life poorly described.
Ficheux Anne‐Sophie +3 more
wiley +1 more source
Journal of Clinical MicrobiologyNon-tuberculous mycobacterial (NTM) skin infections present diagnostic and therapeutic challenges in resource-limited primary care settings. This retrospective study evaluated the diagnosis and treatment of NTM skin infections at a primary care hospital ...
Tianyi Xu +6 more
doaj +1 more source
JEADV Clinical Practice, EarlyView.ABSTRACT Background Pyoderma gangrenosum (PG) is a rare neutrophilic dermatosis associated with systemic inflammatory diseases and malignancy. Although biologic therapies demonstrate efficacy in PG, the extent of their real‐world use remains incompletely characterized.
Rhiannon Grange +4 more
wiley +1 more source