Des-gamma-carboxyprothrombin is a favorable biomarker for the early diagnosis of alfa-fetoprotein-negative hepatitis B virus-related hepatocellular carcinoma [PDF]
Objectives Des-gamma-carboxyprothrombin (DCP) is an important serum biomarker for the clinical screening of hepatocellular carcinoma (HCC). This study aimed to evaluate the value of DCP for the early diagnosis of alpha-fetoprotein (AFP)-negative ...
Zhaobo Liu +3 more
doaj +6 more sources
Prognostic Values of Alpha-Fetoprotein and Des-Gamma-Carboxyprothrombin in Hepatocellular Carcinoma in China: An Analysis of 4792 Patients [PDF]
Yang-Xun Pan,1– 3,* Xu-Qi Sun,1,2,* Zi-Li Hu,1,2,* Wa Xie,1,2 Ke-Xin Nie,4 Ai-Ping Fang,5 Ying-Yao Zhang,4 Yi-Zhen Fu,1,2 Jin-Bin Chen,1,2 Jun-Cheng Wang,1,2 Xin Wang,1,2 Yao-Jun Zhang,1,2 Dan-Dan Hu,1,2 Min-Shan Chen1,2 1Collaborative ...
Pan YX +13 more
doaj +6 more sources
Diagnostic value of alpha-fetoprotein, agglutinin-reactive alpha-fetoprotein, and des-gamma-carboxyprothrombin in hepatitis B virus-related hepatocellular carcinoma [PDF]
Objective This study aimed to explore the use of different combinations of alpha-fetoprotein (AFP), Lens culinaris agglutinin-reactive AFP (AFP-L3), and des-gamma-carboxyprothrombin (DCP) for the early diagnosis of hepatocellular carcinoma (HCC) in ...
Ting Song +7 more
doaj +5 more sources
Utility of serum des-gamma-carboxyprothrombin in the diagnosis of hepatocellular carcinoma among Nigerians, a case-control study. [PDF]
Hepatocellular Carcinoma (HCC) is a common malignancy occurring globally but with a dismal prognosis. Des-gamma-carboxyprothrombin (DCP) has been reported to be more sensitive and specific than Alpha-fetoprotein (AFP) in the diagnosis of HCC among the White population. Its efficacy among the Black population is yet to be established.
Ette AI +3 more
europepmc +5 more sources
Early Tumor Marker Response Predicts Treatment Outcomes in Patients with Unresectable Hepatocellular Carcinoma Receiving Combined Lenvatinib, Immune Checkpoint Inhibitors, and Transcatheter Arterial Chemoembolization Therapy [PDF]
Meng-Chao Luo,1,2,* Jia-Yi Wu,1,3,* Jun-Yi Wu,1,3 Zhong-Tai Lin,1,2 Yi-Nan Li,3 Zhen-Xin Zeng,3 Shao-Ming Wei,1,2 Mao-Lin Yan1,3 1Shengli Clinical Medical College of Fujian Medical University, Fuzhou, Fujian Province, 350001, People’s Republic of
Luo MC +7 more
doaj +2 more sources
Effect of abdominal aortic calcification on long‐term outcomes after the first liver resection in very old patients with hepatocellular carcinoma [PDF]
Aim We previously reported that abdominal aortic calcification is associated with poor overall and recurrence‐free survival after hepatectomy for hepatocellular carcinoma (HCC).
Yosuke Namba +19 more
doaj +2 more sources
Economic evaluation of biomarker-based surveillance for Hepatocellular Carcinoma in Thai patients with Compensated Liver Cirrhosis. [PDF]
ObjectiveHepatocellular carcinoma (HCC) is the leading cause of cancer-related death in Thailand. However, most Thai patients at high risk of HCC lack access to routine surveillance programs.
Nutcha Pinjaroen +7 more
doaj +2 more sources
Development and Validation of a Prognostic Nomogram for Patients with AFP and DCP Double-Negative Hepatocellular Carcinoma After Local Ablation [PDF]
Wenying Qiao,1– 3,* Jiashuo Li,2,* Qi Wang,2,* Ronghua Jin,2,3 Honghai Zhang1 1Interventional Therapy Center for Oncology, Beijing You’an Hospital, Capital Medical University, Beijing, People’s Republic of China; 2Beijing Di’tan Hospital ...
Qiao W, Li J, Wang Q, Jin R, Zhang H
doaj +2 more sources
The Impact of TP53-Induced Glycolysis and Apoptosis Regulator on Prognosis in Hepatocellular Carcinoma: Association with Tumor Microenvironment and Ferroptosis [PDF]
Introduction: TP53-induced glycolysis and apoptosis regulator (TIGAR) is a p53 target protein that has critical roles in glycolysis and redox balance. The reports about the effect of TIGAR on prognosis and its biological role in hepatocellular carcinoma (
Katsuya Toshida +12 more
doaj +2 more sources
ASSESSMENT OF THE VALUE OF MEAN PLATELET VOLUME, DES GAMMA CARBOXY PROTHROMBIN AND ALPHA FETO PROTEIN IN EARLY DETECTION OF HCC [PDF]
Background: Hepatocellular carcinoma (HCC) is the commonest primary hepatic neoplasm. The gold standard HCC biomarker is alfa-feto protein (AFP), also mean platelet volume (MPV) is increased in many inflammatory disorders and numerous neoplasms.
Omnia Ellaithy +3 more
doaj +1 more source

