Results 171 to 180 of about 60,642 (273)

Quantitative Proteomics and CRISPR/Cas9 Editing Reveal UPR‐Mediated Control of Immunoglobulin Homeostasis in Hybridomas

open access: yesAdvanced Science, Volume 13, Issue 17, 23 March 2026.
BCR sequencing and subclone analysis correlated immunoglobulin (Ig) chain loss in dysfunctional hybridomas with disrupted monoclonal antibody homeostasis. Proteomics‐guided CRISPR/Cas9 editing revealed that the unfolded protein response (UPR) regulates aberrant Ig synthesis.
Rubing Zou   +9 more
wiley   +1 more source

Attenuated Bacteria‐Based Tumor Therapy: Clinical Application Risks, Marketing Approval Restrictions, and Coping Strategies

open access: yesAdvanced Science, Volume 13, Issue 16, 18 March 2026.
This review comprehensively overviews attenuated bacteria‐based tumor therapy, highlighting key methodologies and recent progress. It examines strategies for enhancing safety, stabilizing efficacy, optimizing manufacturing, and navigating regulatory pathways.
Yucheng Liu   +8 more
wiley   +1 more source

Modification Strategies of Carbon‐Based Electrodes From Structural Regulation to Multifunctional Integration

open access: yesAdvanced Science, Volume 13, Issue 14, 9 March 2026.
Tracing the evolution from structural regulation to multifunctional integration, this paper systematically analyzes modification strategies for carbon‐based electrodes. It evaluates how element doping, surface functionalization, and composite material design affect the electrode performance, and offers perspectives on future applications and challenges
Yunlei Wang   +4 more
wiley   +1 more source

Future trends of desalination and wastewater treatment accounting for risks of maladaptation

open access: yes
Andrijevic M   +6 more
europepmc   +1 more source

Towards Climate Neutrality by 2050: Role of Aluminum for Short‐ and Long‐Term Energy and Hydrogen Storage

open access: yesAdvanced Energy Materials, Volume 16, Issue 10, 11 March 2026.
The Aluminum energy storage cycle involves the use of renewable energy for Al production and the generation of heat (dry cycle) and heat and H2 (wet cycle) for energy production via Al‐steam combustion. ABSTRACT Reaching climate neutrality by 2050 requires innovative long‐term energy storage (LTES) solutions beyond the current use of fossil fuels ...
Lorenzo Trombetti   +2 more
wiley   +1 more source

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