Results 181 to 190 of about 763,739 (333)

Extending the firm versus industry debate into social enterprises: A multilevel analysis on Spanish cooperatives 2008–2023

open access: yesAnnals of Public and Cooperative Economics, EarlyView.
Abstract An important debate in the field of strategy and industrial organization economics has long focused on whether the industry environment or firm idiosyncrasies have a greater impact on firm performance. However, cooperatives have been excluded from this inquiry, despite profits being the primary means to achieve their social objectives.
Pablo Doucet, Marta Solórzano‐García
wiley   +1 more source

Desarrollando sistemas de información centrados en la calidad de datos Developing information systems focused on data quality

open access: yesIngeniare: Revista Chilena de Ingeniería, 2013
Los Sistemas de Información se pueden comparar con los sistemas de fabricación de productos en el sentido que estos últimos generan productos físicos a partir de materia prima, y los primeros generan productos de información a partir de datos puros. Esta
Angélica Caro   +2 more
doaj  

14‐3‐3σ up‐regulation in the temporal cortex associates with tau pathology and reactive astroglia in Lewy body disorders

open access: yesBrain Pathology, EarlyView.
14‐3‐3 protein homeostasis is disrupted in Lewy body pathology, showing a diminution of six isotypes and overexpression of stratifin. The latter was associated with stratifin colocalization with tau pathology and reactive astrocytes. Platelets, as a peripheral biomarker source, mirrored inversely cortical 14‐3‐3 gene expression patterns in dementia ...
Laura Marsal‐García   +13 more
wiley   +1 more source

Rapid generation of prion disease models using AAV‐delivered PrP variants in knockout mice

open access: yesBrain Pathology, EarlyView.
We developed a rapid AAV‐based system to generate prion disease models in weeks rather than months. Following systemic AAV9P31 delivery of modified PrP to knockout mice, we achieved brain‐wide expression and successful propagation of both classical (RML) and atypical (GSS‐A117V) prion strains.
Maitena San‐Juan‐Ansoleaga   +11 more
wiley   +1 more source

Synergistic antiviral activity against human adenovirus through combination of itraconazole and brincidofovir

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Human adenovirus (HAdV) causes respiratory or gastrointestinal tract infections depending on the virus subtype. While HAdV infections are generally self‐limiting in immunocompetent people, they can result in significant morbidity and mortality in immunocompromised adults and children.
Mohamed Zamzamy   +16 more
wiley   +1 more source

Testing the Island Effect in a Highly Mobile Pollinator: Wing Morphological Divergence in Euglossa mixta from Continental and Insular Panama. [PDF]

open access: yesAnimals (Basel)
Añino Y   +11 more
europepmc   +1 more source

Divergence in μ and δ opioid receptor pharmacology in neurons and antinociceptive efficacy in neuropathic pain: Insights from MP135 and CYM51010

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and purpose Opioids targeting the μ opioid receptor remain largely ineffective in neuropathic pain conditions, emphasizing the need for novel therapeutic strategies. MP135 was reported to reduce thermal nociception in naive animals by activating μ‐δ opioid receptor heteromers.
Perrine Inquimbert   +13 more
wiley   +1 more source

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