Results 191 to 200 of about 772,886 (306)

Vitality and Challenging Commitment in Times of Digital Intensification: Evidence for Healthy Educational Organizations Based on Teacher Engagement in Chile. [PDF]

open access: yesEur J Investig Health Psychol Educ
Sandoval-Obando E   +5 more
europepmc   +1 more source

Rapid generation of prion disease models using AAV‐delivered PrP variants in knockout mice

open access: yesBrain Pathology, EarlyView.
We developed a rapid AAV‐based system to generate prion disease models in weeks rather than months. Following systemic AAV9P31 delivery of modified PrP to knockout mice, we achieved brain‐wide expression and successful propagation of both classical (RML) and atypical (GSS‐A117V) prion strains.
Maitena San‐Juan‐Ansoleaga   +11 more
wiley   +1 more source

Desarrollo de software de reconocimiento de matrículas de coche

open access: yes, 2014
En el presente trabajo final de carrera se pretende desarrollar un software, utilizando un sistema de visión artificial, que permita detectar automáticamente matrículas a partir de imágenes de coches y extraer el numero con un formato de texto legible por el ordenador. El trabajo se dividirá en dos etapas: • La primera etapa de adaptación con C++, y en
openaire   +2 more sources

The L108I polymorphism in mouse prion protein drives spontaneous disease and enhances transmission of atypical and classical prion strains

open access: yesBrain Pathology, EarlyView.
A single amino acid change (L108I) combined with PrP overexpression drives spontaneous atypical prion formation in mice, enabling also efficient propagation of diverse prion strains. This model allows studying how spontaneous prion diseases arise and provides powerful tools for investigating strain emergence, transmission barriers, and mechanisms ...
Hasier Eraña   +20 more
wiley   +1 more source

Antimicrobial Effect of Cellulose Nanofibrils (CNFs) and Biobased Additives in Polyvinyl Alcohol Nanocomposite Materials for Sustainable Food Packaging Application. [PDF]

open access: yesPolymers (Basel)
Valdebenito F   +10 more
europepmc   +1 more source

Enhancing antitumour response to proteasome inhibitors with inhibitors of insulin‐degrading enzyme, a new molecular vulnerability in multiple myeloma

open access: yesBritish Journal of Pharmacology, EarlyView.
Inhibitors of insulin‐degrading enzyme boost PI cytotoxicity through an increased sensitivity of proteasome to PI inhibitors, induction of ISR, DNA damage and Myc down‐regulation. They overcome PI resistance in vitro and induce tumour regression in vivo.
Laetitia Lesire   +28 more
wiley   +1 more source

The collective application of shorebird tracking data to conservation

open access: yesConservation Biology, EarlyView.
Abstract Addressing urgent conservation issues, such as the drastic declines of North American migratory birds, requires creative, evidence‐based, efficient, and collaborative approaches. The abundance of over 50% of monitored North American shorebird populations has declined by over 50% since 1980. To address these declines, we developed a partnership
Autumn‐Lynn Harrison   +71 more
wiley   +1 more source

Estado de progreso en el desarrollo de proyectos software apoyado por Semat y QFD

open access: yesIngeniare: Revista Chilena de Ingeniería
El éxito en el desarrollo de un proyecto de software consiste en cumplir con los objetivos para los cuales fue concebido. Un aspecto fundamental radica en medir el estado de progreso del proyecto a través del seguimiento, determinando qué controles se ...
Luis Fernando Castro Rojas   +1 more
doaj  

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