Results 211 to 220 of about 772,886 (306)

Polyesterase activity and thermostability of carboxylesterases from Thermoleophilum album YS‐3

open access: yesThe FEBS Journal, EarlyView.
Three novel α/β‐hydrolases from thermophilic bacterium Thermoleophilum album display carboxylesterase and polyesterase activity. These enzymes hydrolyse PET, PLA and PCL both at high and moderate temperatures. TA21 shows superior activity, efficiently converting MHET to terephthalic acid. Structural features underlying substrate binding highlight their
Tatyana N. Chernikova   +6 more
wiley   +1 more source

Testing the Island Effect in a Highly Mobile Pollinator: Wing Morphological Divergence in Euglossa mixta from Continental and Insular Panama. [PDF]

open access: yesAnimals (Basel)
Añino Y   +11 more
europepmc   +1 more source

Investigating transthyretin variants H88R and I107V in amyloid priming: From destabilization to complete dissociation

open access: yesThe FEBS Journal, EarlyView.
Investigated mutations in transthyretin (TTR) disrupt the F87‐centered hydrophobic core that stabilizes its tetrameric structure. The mild I107V mutation weakens inter‐chain packing, while H88R fully abolishes tetramer formation, yielding a monomeric, aggregation‐prone form. Structural, biophysical, and computational analyses reveal that both mutations
István L. Bódy   +7 more
wiley   +1 more source

¿Porque fracasan los proyectos de desarrollo de software?

open access: yes, 2014
La investigación permitió elaborar una relación actualizada de las causas principales por las cuales los proyectos de desarrollo de software fracasan, tomando como punto de partida la revisión de lo investigado por otros autores y contrastándolo con los testimonios de profesionales activos que lideran o hacen parte de equipos de trabajo que se dedican ...
openaire   +1 more source

Persistent in vitro nociceptor hyperexcitability and axonal retraction produced by repeated paclitaxel doses

open access: yesThe FEBS Journal, EarlyView.
Repeated paclitaxel exposure causes long‐lasting nociceptor hyperexcitability and axonal retraction in adult sensory neurons. Using a long‐term primary nociceptor culture, we show that hyperexcitability is mediated by sequential upregulation of NaV1.8, TRPV1, TRPA1, and TRPM8 channels.
Angela Lamberti   +3 more
wiley   +1 more source

Melanoma cell inoculation improves cognitive impairment in the 5xFAD mouse model of Alzheimer's disease. [PDF]

open access: yesSci Rep
Bruna-Jara B   +15 more
europepmc   +1 more source

Proyecto de desarrollo de software "This is it"

open access: yes, 2014
Fil: Galván, Paula Daniela. Universidad de Buenos Aires. Facultad de Ciencias Económicas. Buenos Aires, Argentina.
openaire   +1 more source

What Job Would You Apply To? Findings on the Impact of Language on Job Searches

open access: yesGender, Work &Organization, EarlyView.
ABSTRACT This study examines whether gender‐inclusive language in job advertisements can increase women's interest in applying for male‐dominated occupations. We implemented a discrete choice experiment with 5679 participants in Argentina, Chile, Colombia, Mexico, and Peru. Each respondent evaluates multiple paired ads for the same job with job content
Ana Maria Diaz   +3 more
wiley   +1 more source

Identification of 14-3-3 Proteins as Binding Partners of TRP Channels. [PDF]

open access: yesJ Chem Inf Model
Peña-Vilches N   +10 more
europepmc   +1 more source

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