Results 1 to 10 of about 7,949 (97)

d-Pinitol promotes tau dephosphorylation through a cyclin-dependent kinase 5 regulation mechanism: A new potential approach for tauopathies? [PDF]

open access: yesBr J Pharmacol, 2022
Background and Purpose Recent evidence links brain insulin resistance with neurodegenerative diseases, where hyperphosphorylated tau protein contributes to neuronal cell death. In the present study, we aimed to evaluate if d‐pinitol inositol, which acts as an insulin sensitizer, affects the phosphorylation status of tau protein.
Medina-Vera D   +12 more
europepmc   +2 more sources

Empagliflozin reduces vascular damage and cognitive impairment in a mixed murine model of Alzheimer's disease and type 2 diabetes [PDF]

open access: yesAlzheimers Res Ther, 2020
Background Both Alzheimer's disease (AD) and type 2 diabetes (T2D) share common pathological features including inflammation, insulin signaling alterations, or vascular damage.
Alves-Martinez, Pilar   +8 more
core   +2 more sources

UEG Week 2023 Poster Presentations [PDF]

open access: yesUnited European Gastroenterol J, 2023
United European Gastroenterology Journal, Volume 11, Issue S8, Page 535-1498, October 2023.
europepmc   +2 more sources

UEG Week 2022 Oral Presentations [PDF]

open access: yesUnited European Gastroenterol J, 2022
United European Gastroenterology Journal, Volume 10, Issue S8, Page 9-184, October 2022.
europepmc   +2 more sources

UEG Week 2024 Moderated Posters [PDF]

open access: yesUnited European Gastroenterol J
United European Gastroenterology Journal, Volume 12, Issue S8, Page 201-664, October 2024.
europepmc   +2 more sources

Propuesta de modelado de línea de producto de software para aplicaciones mashup

open access: yesInformes Científicos y Técnicos (Universidad Nacional de la Patagonia Austral), 2021
Un mashup es una aplicación compuesta que integra dos o más tipos de componentes disponibles en la Web, creando un nuevo valor a partir de los componentes o artefactos que la componen, permitiendo su reuso y proporcionando una funcionalidad que no ...
Héctor Reinaga   +2 more
doaj   +1 more source

Looking through a policy window with tinted glasses: Setting the agenda for U.S. AI policy

open access: yesReview of Policy Research, Volume 40, Issue 5, Page 729-756, September 2023., 2023
Abstract The policy agenda is currently being established for artificial intelligence (AI), a domain marked by complex and sweeping implications for economic transformation tempered by concerns about social and ethical risks. This article reviews the United States national AI policy strategy through extensive qualitative and quantitative content ...
Daniel S. Schiff
wiley   +1 more source

Estuarine Salinity Response to Freshwater Pulses

open access: yesJournal of Geophysical Research: Oceans, Volume 127, Issue 11, November 2022., 2022
Abstract Freshwater pulses (during which river discharge is much higher than average) occur in many estuaries and strongly impact estuarine functioning. To gain insight into the estuarine salinity response to freshwater pulses, an idealized model is presented.
Bouke Biemond   +3 more
wiley   +1 more source

Development and psychometric properties of a self‐report instrument for the assessment of sexual behaviour and concerns of people with mild intellectual disabilities (SEBECOMID‐S)

open access: yesJournal of Applied Research in Intellectual Disabilities, Volume 35, Issue 1, Page 134-142, January 2022., 2022
Abstract Background This paper presents a description of the development and psychometric properties of a self‐report instrument for the assessment of sexual behaviour and concerns of people with mild intellectual disabilities (SEBECOMID‐S). Methods and procedures The study included 281 people with mild intellectual disabilities.
María Dolores Gil‐Llario   +4 more
wiley   +1 more source

Inhibition of biofilm formation on polystyrene substrates by atmospheric pressure plasma polymerization of siloxane‐based coatings

open access: yesPlasma Processes and Polymers, Volume 18, Issue 12, December 2021., 2021
Polystyrene plates were coated by atmospheric plasma polymerization of (3‐aminopropyl)triethoxysilane (APTES). The coatings induced oxidative stress in Pseudomonas aeruginosa bacteria, which caused bacterial extracellular polymeric substances (EPS) overproduction for the first 2 days of incubation. Overproduced EPS inhibited long‐term biofilm formation
Rodolfo Múgica‐Vidal   +9 more
wiley   +1 more source

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