Results 31 to 40 of about 3,953 (185)

Exploring the histopathological signature of repeat‐mediated Fuchs endothelial corneal dystrophy

Acta Ophthalmologica, Volume 104, Issue 3, Page 333-341, May 2026.
Abstract Purpose To determine the histological differences between Fuchs endothelial corneal dystrophy (FECD) cases with and without the most common genetic risk factor, expansion of a CTG repeat (CTG18.1) within the TCF4 gene. Methods Formalin‐fixed paraffin‐embedded corneal tissues were compared retrospectively, and CTG18.1 status was determined from
Anne‐Marie S. Kladny, Nihar Bhattacharyya, Marcos Abreu Costa, Stephen J. Tuft, Caroline Thaung, Alice E. Davidson   +5 more
wiley   +1 more source

Double-pass microkeratome technique for ultra-thin graft preparation in Descemet's stripping automated endothelial keratoplasty

Clinical Ophthalmology, 2012
Maylon Hsu, Walter L Hereth, Majid MoshirfarUniversity of Utah, John A Moran Eye Center, Department of Ophthalmology and Visual Sciences, Salt Lake City, UT, USAAbstract: Endothelial keratoplasty is evolving with increased attention placed on the optical
Hsu M, Hereth WL, Moshirfar M
doaj  

Generation of a Novel Col8a2P2A‐CreERT2 Mouse Line Enables Targeted Genetic Manipulation of Corneal Endothelial Cells and Modeling of Endothelial Decompensation

genesis, Volume 64, Issue 2, April 2026.
ABSTRACT The corneal endothelium is a monolayer of specialized cells that maintains stromal deturgescence and transparency, functions essential for vision. Despite its clinical importance, the developmental origins and homeostatic programs of the endothelium remain poorly understood, in part due to the lack of a lineage‐specific genetic driver.
Yong Yuan, Josiah Holt, Samuel Lorry, Yen‐Chiao Wang, Yueh‐Chiang Hu, Zhixing Ma, Adam Kaufman, Winston Kao, Diego G. Ogando, Chia‐Yang Liu   +9 more
wiley   +1 more source

Descemet's stripping automated endothelial keratoplasty for congenital hereditary endothelial dystrophy

Clinical Ophthalmology, 2012
Hamed M Anwar, AM El Danasoury, AN HashemCorneal and Refractive Surgery Unit, Magrabi Eye Hospital, Jeddah, Saudi ArabiaAbstract: Congenital hereditary endothelial dystrophy (CHED), presents in infancy or early childhood with bilateral clouding of ...
Anwar HM, El Danasoury AM, Hashem AN
doaj  

Major indications for keratoplasty in the eastern province, Saudi Arabia

Saudi Journal of Medicine and Medical Sciences, 2014
Purpose: To determine the leading indications for keratoplasty in the Eastern Province of the Kingdom of Saudi Arabia (KSA) over a 5 years period (2005-2010) and to compare these indications with previously published studies.
Khalid Arfaj, Reem Abdulqader
doaj   +1 more source

High‐Purity Functional Corneal Endothelial Cells From Human Induced Pluripotent Stem Cells via a Novel Wash‐Out Method

MedComm, Volume 7, Issue 4, April 2026.
iPSC‐derived corneal endothelial cells purified via a novel wash‐out method show high functional fidelity, resemble primary CECs, and restore corneal clarity in vivo, offering a scalable alternative to donor transplantation. ABSTRACT Corneal endothelial failure can cause blindness, with transplantation as the only treatment.
Eun‐Ah Ye, Changmin Kim, Minah Jeon, Yeji Yoon, Jiyoon Park, Ryun Hee Lee, Carson Yu, Ho Seok Chung, Jae Yong Kim, David Myung, Hun Lee   +10 more
wiley   +1 more source

Fuchs endothelial corneal dystrophy: current perspectives

Clinical Ophthalmology, 2016
Gustavo Vedana, Guadalupe Villarreal Jr, Albert S Jun Wilmer Eye Institute, Johns Hopkins Medical Institutions, Baltimore, MD, USA Abstract: Fuchs endothelial corneal dystrophy (FECD) is the most common corneal dystrophy and frequently results in ...
Vedana G, Villarreal Jr G, Jun AS
doaj  

Effects of COVID‐19 on Corneal Transplants Across the Five Regions of Brazil and Trends in Post‐Pandemic Recovery—A Cross‐Sectional Study

Health Science Reports, Volume 9, Issue 2, February 2026.
ABSTRACT Background and Aims The COVID‐19 pandemic significantly disrupted global eye health services, including corneal transplants. This study evaluates the pandemic's long‐term impact on corneal transplantation across Brazil's five regions, highlighting national and regional recovery trends.
Josue Geraldo Lessa, Amélia Soares de Melo, Leandro Vassuler Baldon, Bernardo G. L. Carvalho, Nathalia Sernizon Guimaraes, Aleida N. Soares, Bruno Lovaglio Cançado Trindade, Fernanda Ludolf   +7 more
wiley   +1 more source

Intraoperative use of spectral-domain optical coherence tomography during Descemet’s stripping automated endothelial keratoplasty

Clinical Ophthalmology, 2012
Chelvin CA Sng1,2, Federico Luengo Gimeno1, Jodhbir S Mehta1,2, Hla Myint Htoon1, Donald T Tan1,21Singapore Eye Research Institute and Singapore National Eye Center, 2Department of Ophthalmology, National University Health System, SingaporePurpose: To ...
Sng CCA, Luengo Gimeno F, Mehta JS, Htoon HM, Tan DT   +4 more
doaj  

Quality of life and participation after corneal transplantation and potential predictors: A multicenter prospective cohort study

Acta Ophthalmologica, Volume 104, Issue 1, Page 52-64, February 2026.
Abstract Purpose To evaluate the long‐term effect of corneal transplantation on health‐ and vision‐related quality of life, visual functioning, and societal participation, and to assess potential predictors. Methods We conducted a multicenter prospective cohort study in 11 Dutch hospitals and eye clinics.
E. B. M. Elsman, D. Van der Meij, H. P. A. Van der Aa, N. Santana, M. C. Bartels, M. Zaal, Y. Y. Cheng, R. M. M. A. Nuijts, G. H. M. B. Van Rens, R. M. A. Van Nispen   +9 more
wiley   +1 more source