Results 31 to 40 of about 1,925 (175)

Pathological classification of Fuchs endothelial corneal dystrophy into several types and their relationships with CTG18.1 expansion repeats

open access: yesThe Journal of Pathology, Volume 269, Issue 2, Page 182-196, June 2026.
Abstract Late‐onset Fuchs endothelial corneal dystrophy (FECD) is the most common primary disease of the corneal endothelium and the leading indication for corneal transplantation in Western countries. It is characterized by progressive accumulation, over two to three decades, of extracellular matrix (ECM) components in Descemet's membrane (DM ...
Hanielle Vaitinadapoulé   +45 more
wiley   +1 more source

Triamcinolone Acetonide-Assisted Descemetectomy for Retained Descemet Membrane

open access: yesCase Reports in Ophthalmology, 2018
We present a case of decreased vision due to the presence of retained Descemet membrane (DM) following Descemet stripping automated endothelial keratoplasty (DSAEK) and penetrating keratoplasty (PKP). A 78-year-old male presented postoperatively from PKP
Ariel Tyring, Oliver Chang, Hoon Jung
doaj   +1 more source

Descemet-stripping Automated Endothelial Keratoplasty—A Review

open access: yesUS Ophthalmic Review, 2009
Descemet-stripping automated endothelial keratoplasty (DSAEK) has become the procedure of choice to treat corneal endothelial dysfunction. The technique involves replacing the diseased host endothelium with a graft consisting of a thin layer of posterior stroma, Descemet membrane, and endothelium.
Jimmy K Lee, Anita M Hwang
openaire   +1 more source

The Impact of Real‐Time Data Analytics on Infection Prevention and Control Practices in Ophthalmology: A Nursing Perspective on Patient Outcomes and Cost‐Effectiveness

open access: yesNursing &Health Sciences, Volume 28, Issue 2, June 2026.
ABSTRACT Ophthalmic surgeries pose infection risks. Traditional control methods rely on manual monitoring, creating a need for more precise, data‐driven nursing models. This study evaluated the effectiveness of real‐time data analysis in improving ophthalmic infection prevention and control outcomes.
Zhenhui Chen   +3 more
wiley   +1 more source

Descemet’s stripping automated endothelial keratoplasty and penetrating keratoplasty for Fuchs’ endothelial dystrophy [PDF]

open access: yesActa Ophthalmologica, 2009
Abstract.Purpose:  To compare the outcome of Descemet’s stripping endothelial keratoplasty (DSAEK) to that of penetrating keratoplasty (PK) in patients with Fuchs’ endothelial dystrophy.Methods:  The first 20 patients who underwent DSAEK at the Department of Ophthalmology, Aarhus University Hospital were compared to 20 patients treated with classic PK.
Hjortdal, Jesper, Ehlers, Niels
openaire   +3 more sources

Exploring the histopathological signature of repeat‐mediated Fuchs endothelial corneal dystrophy

open access: yesActa Ophthalmologica, Volume 104, Issue 3, Page 333-341, May 2026.
Abstract Purpose To determine the histological differences between Fuchs endothelial corneal dystrophy (FECD) cases with and without the most common genetic risk factor, expansion of a CTG repeat (CTG18.1) within the TCF4 gene. Methods Formalin‐fixed paraffin‐embedded corneal tissues were compared retrospectively, and CTG18.1 status was determined from
Anne‐Marie S. Kladny   +5 more
wiley   +1 more source

Cataract surgery after Descemet stripping endothelial keratoplasty

open access: yesIndian Journal of Ophthalmology, 2012
Management of endothelial dysfunction in phakic patients is sometimes a dilemma for corneal surgeons. Phakic patients with visually significant cataract and endothelial dysfunction are preferably managed by performing combined cataract surgery with ...
Sunita Chaurasia   +2 more
doaj   +1 more source

Generation of a Novel Col8a2P2A‐CreERT2 Mouse Line Enables Targeted Genetic Manipulation of Corneal Endothelial Cells and Modeling of Endothelial Decompensation

open access: yesgenesis, Volume 64, Issue 2, April 2026.
ABSTRACT The corneal endothelium is a monolayer of specialized cells that maintains stromal deturgescence and transparency, functions essential for vision. Despite its clinical importance, the developmental origins and homeostatic programs of the endothelium remain poorly understood, in part due to the lack of a lineage‐specific genetic driver.
Yong Yuan   +9 more
wiley   +1 more source

Double-pass microkeratome technique for ultra-thin graft preparation in Descemet's stripping automated endothelial keratoplasty

open access: yesClinical Ophthalmology, 2012
Maylon Hsu, Walter L Hereth, Majid MoshirfarUniversity of Utah, John A Moran Eye Center, Department of Ophthalmology and Visual Sciences, Salt Lake City, UT, USAAbstract: Endothelial keratoplasty is evolving with increased attention placed on the optical
Hsu M, Hereth WL, Moshirfar M
doaj  

High‐Purity Functional Corneal Endothelial Cells From Human Induced Pluripotent Stem Cells via a Novel Wash‐Out Method

open access: yesMedComm, Volume 7, Issue 4, April 2026.
iPSC‐derived corneal endothelial cells purified via a novel wash‐out method show high functional fidelity, resemble primary CECs, and restore corneal clarity in vivo, offering a scalable alternative to donor transplantation. ABSTRACT Corneal endothelial failure can cause blindness, with transplantation as the only treatment.
Eun‐Ah Ye   +10 more
wiley   +1 more source

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