Results 171 to 180 of about 400,448 (292)

Intravascular ultrasound-guided percutaneous treatment of late-presenting left anterior descending artery compression after penetrating cardiac trauma in a young adult: a case report. [PDF]

Eur Heart J Case Rep
Özdamar H, Hökerek DM, Abud B, Ayça B, Özpelit ME.   +4 more
europepmc   +1 more source

PLXDC2 siRNA‐Mediated Intervention Attenuates Microglial Senescence Through cGAS‐STING Signaling

Advanced Science, EarlyView.
PLXDC2 was identified as a microglial target in Parkinson's disease through human and mouse single‐cell analyses. Ferritin‐armed biomimetic nanovesicles delivered PLXDC2 siRNA, deferoxamine, and CeO2 nanoparticles across the blood–brain barrier, reducing cGAS‐STING activation, iron burden, oxidative stress, and senescence in microglia, thereby ...
Heyue Lu, Zitian Zheng, Feiran Wang, Huanhuan Luo, Fei Ju, Yucheng Zhu, Zheng Zhou, Jie Sun, Zhenghui Qiu, Xiang Luo, Zhongzheng Jia, Jianquan Wang, Hongjie Huang, Bo Zhang   +13 more
wiley   +1 more source

Endoscopic ultrasound-guided fine-needle biopsy of abdominal lymphadenopathy in Kimura's disease. [PDF]

Endoscopy
Ding S, Cao L, Liu Y, Zhou Q, Zheng S, Li Q.   +5 more
europepmc   +1 more source

Palaeoproteomic Deconvolution of Physical and Genetic Collagen Mixtures

Advanced Science, EarlyView.
ClassiCOL_v2 uses a novel “peptide patching” framework that treats any collagen sample as a patchwork of peptide sequences derived from phylogenetically related species. This allows the algorithm to simultaneously resolve two previously intractable problems: multi‐species samples and/or database deficiencies.
Ian Engels, Tristan Dedrie, Synnøve K. Mo, Simon Van de Vyver, Thijs R. A. Vandenbroucke, Kévin Di Modíca, Jan Decher, Alice Toso, Dieter Deforce, Simon Daled, Alexandra Burnett, Grégory Abrams, Maarten Dhaenens   +12 more
wiley   +1 more source

Delayed Descending Thoracic Aortic Laceration Caused by a Posterior Rib Fracture Fragment: A Case Report. [PDF]

Surg Case Rep
Yoden M, Ishihara D, Shibata K, Ueda K, Shiratori T, Kataoka Y, Kawaguchi Y, Hanaoka J, Shoji F.   +8 more
europepmc   +1 more source

Unidentified spelunker descending cave

Photo showing an unidentified spelunker (probably an Alpine Mountain Club member) descending a ...

core  

Neuron‐Derived Vesicular circMagi1 Restrains Vascular Repair After Ischemic Stroke by Promoting TRIM65‐Mediated ANXA2 Degradation

Advanced Science, EarlyView.
After ischemic stroke, injured neurons transfer circMagi1 to endothelial cells through extracellular vesicles. Within endothelial cells, circMagi1 binds ANXA2 and enhances its engagement with TRIM65, promoting ANXA2 ubiquitination and proteasomal degradation to constrain angiogenic repair.
Youkun Bi, Qun Liu, Baohua Zou, Wenyuan Wang, Xinlong Qiao, Lin Gao, Chaoxu Miao, Ningning Huang, Shuqing Tang, Rui Guo, Changqing Zeng, Ce Jia, Yuanchao Xue, Xuejun Guo, Jianjun Chen, Huiwen Wang, Guangju Ji   +16 more
wiley   +1 more source

The "GABAergic Brake" on the Spinal Defecation Reflex: A Proposed Neurobiological Model Explaining Clozapine- and Benzodiazepine-Induced Gastrointestinal Hypomotility and Ogilvie's Syndrome. [PDF]

Neuropsychopharmacol Rep
Nagamine T.
europepmc   +1 more source

Aspirin‐Derived Salicyl‐CoA Drives Histone Lysine Salicylation Regulated by CBP and SIRT2

Advanced Science, EarlyView.
Aspirin‐derived salicyl‐CoA serves as a previously unrecognized acyl donor for protein lysine salicylation. This study identifies histone lysine salicylation as a reversible epigenetic modification regulated by CBP and SIRT2, expanding the biochemical actions of aspirin beyond its canonical acetylation‐dependent mechanisms and providing a new framework
Facai Zhang, Chuanzan Zhou, Jiaoyan He, Pengpeng Huang, Rong Zhang, Huan Hu, Meng Jiao, Linyi Hu, Feng Liu, Xiaolong Qi, Xiang He, Yunkai Yang, Y Eugene Chinn, Dechao Feng, Dahong Zhang, Qi Zhang   +15 more
wiley   +1 more source

Intra-abdominal Versus Descending Thoracic Cannulation Techniques for Abdominal Normothermic Regional Perfusion. [PDF]

Transplant Direct
Boyne G, Walker OC, Du J, Bayer J, Danobeitia JS, Funk G, Gupta A, Lee SH, Martinez E, Monday K, Noesges S, Rayle M, Testa G, Wall A.   +13 more
europepmc   +1 more source