Results 151 to 160 of about 3,572,618 (307)
Can large language models accurately compute descriptive statistics from structured datasets? A comparative evaluation of ChatGPT and Claude. [PDF]
Sebo P, Wang T.
europepmc +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Beyond descriptive SWOT in pharmacy strategy: A quantitative framework for leaders, managers and educators from prioritization to strategic response. [PDF]
Odeh M, Harb KA.
europepmc +1 more source
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
Recurrent and system-specific model-attribution patterns in PISA 2022 science performance across nine education systems. [PDF]
Liu M, Bai X, Li X, Jin W, Jin W.
europepmc +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
A descriptive account of the Bjokapakha language
Since 2012, I have conducted field research in Geneva with two speakers of the Bjokapakha language, a member of the Tshangla subgroup of Tibeto-Burman. Bjokapakha is spoken in the Bjoka geo (rged-ḥog) in the southeast of the Zh’ämgang district in Bhutan.
Grollmann, Selin
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