Results 101 to 110 of about 1,911,987 (302)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Economic and competence regions: a descriptive analysis of Danish regions [PDF]

open access: yes
The prosperity of the capital city and surrounding area has been used as one fundamental argument for localisation of large foreign companies. But recent research on regional systems of innovation has emphasised, not just the structure of the system ...
Knudsen, Mette Praest
core  

Descriptive analysis of adverse events following immunization with oral cholera vaccine in Lebanon

open access: yesFrontiers in Public Health
BackgroundA national Oral Cholera Vaccine (OCV) Euvichol-Plus® campaign was launched in Lebanon, in response to the first outbreak in three decades, recorded in October 2022. The OCV vaccination campaign was carried out between November 2022 and February
Abeer Zeitoun   +6 more
doaj   +1 more source

La localización de la clase creativa en los municipios españoles Discusión conceptual-operativa y análisis descriptivo

open access: yesEMPIRIA: Revista de Metodología de Ciencias Sociales, 2014
In spite of critics received, the creative class concept is nowadays a central topic in the literature on territorial development. After a critical review of this concept, a proposal to measurement that concept in Spanish municipals is made using the ...
Cristina Mateos Mora   +1 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

A descriptive analysis of overviews of reviews published between 2000 and 2011.

open access: yes, 2012
Background: Overviews of systematic reviews compile data from multiple systematic reviews (SRs) and are a new method of evidence synthesis. Objectives: To describe the methodological approaches in overviews of interventions.
Hartling, L.   +3 more
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

AN ANALYSIS OF DESCRIPTIVE TEXT WRITING COMPOSED BY THE HIGH AND THE LOW ACHIEVERS OF THE EIGHTH GRADE STUDENTS OF SMPN SUKORAMBI JEMBER

open access: yes, 2013
Writing is one of four language skills in English that students have to learn in Indonesia. However, there is not any research which analyzes qualitatively the students’ writing, especially in the genre of descriptive.
Setyo Utami
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Descriptive analysis of extra-curricular program outcome attaintment: A case study of Universiti Malaysia Pahang [PDF]

open access: yes, 2019
This study presents the descriptive analysis of students’ performance in extra-curricular activities at Universiti Malaysia Pahang (UMP). The data analysed are students from all bachelor degree programme at UMP of year 2015 to 2018.
Siti Zanariah, Satari   +3 more
core  

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