Results 171 to 180 of about 2,735,927 (294)

Descriptive Epidemiology of Game-Related Youth Flag Football Injuries. [PDF]

J Athl Train, 2023
Foss KDB, Khoury JC, Eisenmann JC, Cappaert TA.   +3 more
europepmc   +1 more source

Epidemiology

Background.Spatial epidemiology has emerged as an important subfield of epidemiology over the past quarter century. We trace the origins of spatial epidemiology and note that its emergence coincided with technological developments in spatial statistics ...

core  

Transient Sleep Deprivation Induces Persistent Auditory Neuropathy via ROS‐Initiated Neuroinflammation and BK Channel Suppression

Advanced Science, EarlyView.
Sleep disturbance severity closely tracks hearing loss in a clinical cohort, yet the mechanistic link remains unclear. Acute sleep deprivation is shown to trigger transient cochlear oxidative stress that switches into a self‐sustaining neuroinflammatory state, suppressing BK channels and causing irreversible synaptopathy.
Dan Chen, Ying Ma, Lixuan Huang, Xin Chen, Fanliang Kong, Zhenzhou Qian, Mingyue Guan, Xinlin Wang, Yanyan Yang, Shasha Zhang, Peng Li, Renjie Chai   +11 more
wiley   +1 more source

Descriptive epidemiology of opportunistic infections among patients with advanced HIV disease in Kinshasa, Democratic Republic of Congo. [PDF]

BMC Infect Dis
Bakana LM, Mpika DM, Yobi DM, Kabututu PZ, Mwasomi PT, Ditondo P, Mambimbi MM, Mboyo AN, Sequeira TK, Lagrou K, Mvumbi GL, Zono BB.   +11 more
europepmc   +1 more source

Single‐Nucleus Atlas of Spinal Sarcopenia Patients Reveals Disruption of Quiescent and Regenerative Satellite Cell Niches in Fatty‐Infiltrated Muscle

Advanced Science, EarlyView.
Mechanisms of Fatty Infiltration and Muscle Degeneration. Clinical metadata identified intramuscular fat accumulation as an independent driver of muscle mass decline. Single‐nucleus RNA sequencing of spinal sarcopenia muscle revealed adipogenic reprogramming of fibro‐adipogenic progenitors, satellite‐cell niche disruption, and elevated levels of the ...
Wenkai Wu, Renxian Wang, Dingding Wang, Quanzhong Ren, Ling Wang, Fangfang Duan, Guihe Yang, Ruixuan Yu, Yi Wang, Yingyu Zhang, Zetong Zang, Chuqi Li, Weijia Liu, Wenshuang Zhang, Yi Yuan, Zitong Cheng, Xiaoguang Cheng, Junbo Liang, Yajun Liu   +18 more
wiley   +1 more source

The GPX3‐VCAM1 Axis Gates Pro‐Fibrotic Tubule Cell Fate in Hyperuricemic Nephropathy

Advanced Science, EarlyView.
Hyperuricemia induces NLRP3 inflammasome signaling activation and downregulation of GPX3 in proximal tubular epithelial cells, leading to oxidative stress–driven VCAM1 upregulation, emergence of pro‐fibrotic proximal tubule cells, macrophage recruitment, and renal fibrosis.
Yunfei Qi, Qiang Zhao, Yue Lve, Yaming Yuan, Tingting Zhou, Yue Yuan, Dexi Wu, Yifan Tang, Yan Liu, Zhigang Li, Chunping Jiang, Qiurong Ding   +11 more
wiley   +1 more source

Correction: Real-world evidence from the first online healthcare analytics platform-Livingstone: Validation of its descriptive epidemiology module. [PDF]

PLOS Digit Health
PLOS Digital Health Editors.
europepmc   +1 more source

Proteogenomic Profiling of Idiopathic Pulmonary Arterial Hypertension Identifies Sex‐Differential Proteins and Candidate Therapeutic Targets

Advanced Science, EarlyView.
An integrated proteogenomic analysis of 44,137 predominantly European‐ancestry UK Biobank participants aged 40–69 years identifies 12 robust proteins associated with idiopathic pulmonary arterial hypertension. These proteins define a high‐mortality molecular endotype, support early detection and mortality prediction, reveal sex‐differential proteomic ...
Xinjie Lin, Yangchang Zhang, Yang Pu, Duanke Liu, Tao Lei, Kai Ma, Qiyu He, Zheng Dou, Yuze Liu, Dengyuan Liu, Yinge He, Yanshang Wang, Xiaojiao Zheng, Yanbing Ma, Jianrong Zhou, Weiding Zhai, Binbin Su, Li Chen, Shoujun Li   +18 more
wiley   +1 more source

Evolução da mortalidade por câncer de estômago no Estado do Rio de Janeiro: uma comparação entre a região metropolitana e o interior no período de 1979 a 1986

Cadernos de Saúde Pública
O declínio da mortalidade por câncer de estômago vem sendo verificado em vários países desenvolvidos nos últimos cinqüenta anos. No Estado do Rio de Janeiro, o câncer de estômago foi a segunda causa de óbito por câncer entre homens e a terceira entre ...
Gulnar Azevedo Silva Mendonça
doaj  

Descriptive epidemiology of age at HPV vaccination: Analysis using the 2020 NIS-Teen. [PDF]

Hum Vaccin Immunother, 2023
Bednarczyk RA, Brandt HM.
europepmc   +1 more source