Results 31 to 40 of about 139,114 (288)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Handbook of Research on Visual Computing and Emerging Geometrical Design Tools [PDF]

open access: yes, 2016
Visual computing and descriptive geometry are multidisciplinary fields addressing the handling of images, 3D models, and other computer graphics. These ideas are experiencing a revival due to emergent technologies and applications available to developers.
Giuseppe, Amoruso
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

One Application of the Informatics in the Descriptive Geometry [PDF]

open access: yes, 2010
This work acquaints with a program for interactive computer training to students on the subject "Mutual intersecting of pyramids in axonometry ”. Our software is a set of three modules, which we call "student", "teacher" and "autopilot".
Karaibryamov, Samet, Tsareva, Bistra
core  

Greedy Search for Descriptive Spatial Face Features

open access: yes, 2017
Facial expression recognition methods use a combination of geometric and appearance-based features. Spatial features are derived from displacements of facial landmarks, and carry geometric information.
Benligiray, Burak   +2 more
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Analysis of the use of electronic courses "Descriptive geometry and engineering graphics" [PDF]

open access: yes, 2016
На современном этапе технического развития общества возникла необходимость в изменении стиля преподавания дисциплин инженерного профиля, освоения преподавателями и студентами активных технологий взаимодействия, приближенных к реальной профессиональной ...
Буркова, Светлана Петровна   +2 more
core  

CONSIDERATIONS REGARDING THE EMOTIONAL FACTOR IN ERGONOMICS AND DESIGN

open access: yesJournal of Industrial Design and Engineering Graphics, 2015
Considering the quick development in technology, it is more and more necessary to place the problem of studying the effects of the emotions created, both in terms of design and ergonomics.
DUCA Mioara   +2 more
doaj  

Numerical solution to the Complex 2D Helmholtz Equation based on Finite Volume Method with Impedance Boundary Conditions

open access: yesOpen Physics, 2016
In this paper, the numerical solution to the Helmholtz equation with impedance boundary condition, based on the Finite volume method, is discussed. We used the Robin boundary condition using exterior points.
Handlovičová Angela   +1 more
doaj   +1 more source

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