Results 61 to 70 of about 155,972 (334)

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source

INDUSTRIAL DESIGN AND MODERN EDUCATION

Journal of Industrial Design and Engineering Graphics, 2008
The paper presents a study of modern education regarding the selection and approach of a design theme, its social and psychological impact the aims of the developer of a design product, the key steps in the development of the theme and its completion ...
CRISAN Nour - I., BODEA, Sanda, BUDISAN Tiberiu   +2 more
doaj  

Screencast : promovendo o sucesso na disciplina de geometria descritiva [PDF]

, 2009
Nesta comunicação vamos apresentar um projecto inovador desenvolvido numa turma de 11º ano de escolaridade na disciplina de Geometria Descritiva. A Geometria Descritiva é uma disciplina com elevado grau de insucesso no exame nacional e, no sentido de ...
Coutinho, Clara Pereira, Rocha, Aurora Maria Moreira da   +1 more
core  

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

ABOUT THE HIGH PRECISION PRESCRIBED ON THE DRAWING AND REQUIREMENTS IMPOSED FOR SORTING ASSEMBLING OF AD JOINT PIECES

Journal of Industrial Design and Engineering Graphics, 2009
High precision prescribed on the shop drawing of ad joint pieces within a fit or within a unit imposes certain requirements concerning the assembling modality, concomitantly, the forming methodology of highly precise assembling must be cost-efficiently ...
Popescu Narcisa, Duca Mioara
doaj  

Development of a Prediction Model for Progression Risk in High‐Grade Gliomas Based on Habitat Radiomics and Pathomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate the value of constructing models based on habitat radiomics and pathomics for predicting the risk of progression in high‐grade gliomas. Methods This study conducted a retrospective analysis of preoperative magnetic resonance (MR) images and pathological sections from 72 patients diagnosed with high‐grade gliomas (52 ...
Yuchen Zhu, Yuxi Gong, Weilin Xu, Xingjian Sun, Gefei Jiang, Lei Qiu, Kexin Shi, Mengxing Wu, Yinjiao Fei, Jinling Yuan, Jinyan Luo, Yurong Li, Yuandong Cao, Minhong Pan, Shu Zhou   +14 more
wiley   +1 more source

SYMMETRY – MATHEMATICAL CONCEPTS AND APPLICATIONS IN TECHNOLOGY AND ENGINEERING

Journal of Industrial Design and Engineering Graphics, 2009
This article discusses the relation between the concept of symmetry and its applications in engineering. "Symmetry" is interpreted in a broad sense as repeated, coplanar shape fragments.
Dobre Daniel, Simion Ionel
doaj  

Toward a Semiotic Framework for Using Technology in Mathematics Education: The Case of Learning 3D Geometry [PDF]

, 2004
This paper proposes and examines a semiotic framework to inform the use of technology in mathematics education. Semiotics asserts that all cognition is irreducibly triadic, of the nature of a sign, fallible, and thoroughly immersed in a continuing ...
Nason, Rodney, Yeh, Andy
core   +1 more source

Feasibility and Tolerability of Performing Portable MRI for Neurological Disorders in an Outpatient Neurology Clinic: A Prospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Accessing brain magnetic resonance imaging (MRI) can be challenging, especially for underserved patients, which may lead to disparities in neurological diagnosis. Method This mixed‐methods study enrolled adults with one of four neurological disorders: mild cognitive impairment or dementia of the Alzheimer type, multiple sclerosis ...
Maya L. Mastick, Nomin Enkhtsetseg, Joseph Sadok, Matheus Mochetti, Annabel Sorby Adams, Jennifer Guo, Cristina Trapaga Hacker, Isabella Gomez Hjerthen, Seungwon Lee, Siddharth Satish, Andrew S. Ham, Justin Hill, Denis Balaban, Kevin Kyle, Rebecca L. Gillani, Marcelo Matiello, Aleksandar Videnovic, Eric C. Klawiter, W. Taylor Kimberly, Farrah J. Mateen   +19 more
wiley   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source