Results 111 to 120 of about 2,644,434 (248)

Disrupting gender norms in health systems: making the case for change

, 2019
Restrictive gender norms and gender inequalities are replicated and reinforced in health systems, contributing to gender inequalities in health. In this Series paper, we explore how to address all three through recognition and then with disruptive ...
Fielding-Miller, Rebecca, Dehingia, Nabamallika, Shabalala, Fortunate, Blokhina, Elena, Silverman, Jay G, Huque, Rumana, Saggurti, Niranjan, Kharel, Chandani, Henry, Sarah, Yore, Jennifer, Barasa, Edwine, Morgan, Rosemary, Dey, Arnab, McDougal, Lotus, Klugman, Jeni, Atmavilas, Yamini, Raven, Joanna, Wurie, Haja, Hay, Katherine, Bhan, Nandita, Percival, Valerie, Raj, Anita   +21 more
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Social norms and economic incentives in firms [PDF]

, 2003
This paper studies the interplay between economic incentives and social norms in firms. We introduce a general framework to model social norms arguing that norms stem from agents’ desire for, or peer pressure towards, social efficiency.
Huck, S., Weibull, J., Kubler, D.
core  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Fanning the flames: the interplay between social norms and conservation values in misleading news sharing and evaluation among adolescents

Social Influence
This study investigates the role of injunctive and descriptive social norms and their interplay with conservation values on adolescents' evaluation and sharing of misleading news. The research, conducted with 353 Italian adolescents (mean age = 14.4, SD =
Paolo Giovanni Cicirelli, Carmela Sportelli, Giuseppe Corbelli, Marinella Paciello, Francesca D’Errico   +4 more
doaj   +1 more source

Social-contextual factors interact with masculinity to influence college men's HPV vaccination intentions: The role of descriptive norms, prototypes, and physician gender. [PDF]

J Behav Med, 2022
Peterson LM, Orr JA, Rogelberg SD, Olsen N.   +3 more
europepmc   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Social identity support, descriptive norms, and economic instability in PrEP engagement for emerging adult MSM in the United States. [PDF]

AIDS Care, 2022
Bonett S, Bauermeister J, Meanley S.
europepmc   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Gender Differences in Descriptive Norms as Mediators of a Military Web-Based Alcohol Intervention. [PDF]

J Stud Alcohol Drugs, 2021
Williams J.
europepmc   +1 more source