Results 81 to 90 of about 2,644,434 (248)

Did Descriptive and Prescriptive Norms About Gender Equality at Home Change During the COVID-19 Pandemic? A Cross-National Investigation. [PDF]

Using data from 15 countries, this article investigates whether descriptive and prescriptive gender norms concerning housework and child care (domestic work) changed after the onset of the COVID-19 pandemic.
Saxler, Franziska Magdalena, Danyliuk, Ivan, Dorrough, Angela R., Schmader, Toni, Germano, Adriana, Ishii, Keiko, Froehlich, Laura, Olsson, Maria, Gavreliuc, Alin, Meeussen, Loes, Cheryan, Sapna, Velásquez Díaz, Laura María, Birneanu, Andreea, Lapytskaia Aidy, Christina, Steele, Jennifer, Venegas, Mar, Croft, Alyssa, Estevan-Reina, Lucía, Block, Katharina, Benson-Greenwald, Tessa, Morandini, James, Cavojova, Vladimira, Steffens, Melanie C, Kundtová Klocová, Eva, Martiny, Sarah E, Scheifele, Carolin, Ramis, TamilSelvan, Eisner, Léïla, Kozytska, Inna, van Grootel, Sanne, Henningsen, Levke, López López, Wilson, Fedáková, Denisa, Schuster, Carolin, Martiny, Sarah E., Kulich, Clara, Gavreliuc, Dana, Dorrough, Angela R, Van Laar, Colette, Atkinson, Ciara, de Lemus, Soledad, Steffens, Melanie C., Dar-Nimrod, Ilan, Diekman, Amanda, Hässler, Tabea, Lee Kai Chung, Albert   +45 more
core   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Breaking False Polarization: How Information on Descriptive Norms Mitigates Worry Rooted in Polarization (Mis)perceptions

Social Inclusion
Worry about polarization in society, particularly around the topic of immigration, is widespread despite the lack of substantial evidence supporting the existence of actual polarization of attitudes.
Tom Nijs
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Norms, interests and institutional change [PDF]

, 2005
This paper provides a norms-based account of institutional change. It compares two cases of attempted change, one successful and one unsuccessful. The argument advanced is that norm-based change occurs when the norms are congruent with the perceived ...
Dionyssis G. Dimitrakopoulos, Dimitrakopoulos, Dionyssis G.   +1 more
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Local descriptive body weight and dietary norms, food availability, and 10-year change in glycosylated haemoglobin in an Australian population-based biomedical cohort

BMC Public Health, 2017
Background Individual-level health outcomes are shaped by environmental risk conditions. Norms figure prominently in socio-behavioural theories yet spatial variations in health-related norms have rarely been investigated as environmental risk conditions.
Suzanne J. Carroll, Catherine Paquet, Natasha J. Howard, Neil T. Coffee, Robert J. Adams, Anne W. Taylor, Theo Niyonsenga, Mark Daniel   +7 more
doaj   +1 more source