Results 101 to 110 of about 3,596,410 (291)
, 2012 In a cross-country comparison of 33 European countries, we tested whether a high degree of female representation attenuates the assumed negative impact of gender on political involvement.
Bühlmann, Marc +1 more
core +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Measuring Descriptive Representation
RepresentationStudies of descriptive representation typically use a percentage 'gap' or 'ratio' to measure under- or over-representation. I propose generalisations to the existing approach using measures of disproportionality to measure multigroup representation relative to population benchmarks.
openaire +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Dissertation Project: When does descriptive representation matter?
The representation of social groups in democratic institutions, also defined as descriptive representation, is crucial for people's attitudes towards these institutions.
Verena Reidinger
core +1 more source
METHODS FOR THE REPRESENTATION OF THE HELICOIDAL SURFACE
Journal of Industrial Design and Engineering Graphics, 2017 In this paper there are presented the graphical methods to determine the parameters of an helicoidal stairs. The first part of this paper shows the used methods to generate the helicoidal curves using descriptive geometry methods.
SCURTU Liviu-Iacob +3 more
doaj +4 more sources
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Referendums and political representation
The use of referendums is increasing globally, and as a result, the debate on whether they are a saviour or a danger to democracy has intensified. This chapter contributes to the discussion by examining the merits and challenges of referendums from a ...
Stadelmann-Steffen, Isabelle
core +1 more source