Results 111 to 120 of about 3,596,410 (291)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Gender, politics and media: sterotypical representations. How do we draw the line?
Sfera Politicii, 2015 The article explores specific intersections within the gender, politics and media triangle in order to better understand the positioning of media in regards to political representation of women.
Oana Băluţă
doaj
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Journal of Industrial Design and Engineering Graphics, 2015 This paper presents how descriptive geometry contributes to the achievement of intersections of simple objects and isometric axonometric representation of these intersections.
Mihaela Cotrumba, Alexandru Pintilie
doaj +4 more sources
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
The representation of paganism in midsommar (2019)
, 2021 The unit analysis of this study is the midsommar (2019) film directed by Ari Aster. The study focuses on the representation of paganism in the horror film midsommar. This study uses qualitative descriptive analysis as the method to analyze paganism signs
Muhammad Farkhan, Farah juniar adianti
core
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
This data represents the replication data for the article "The Link Between Educational Socialization, Descriptive Representation, and Substantive ...
Christopher Stout
core +1 more source
Descriptive and Directive Representation
, 2018 Abstract A distinction between descriptive and directive representations can readily be drawn within the varitel framework. Neither decoupling, nor the ability to keep track of goal satisfaction, are constitutive of having directive content, although both imply that content will be directive.
openaire +1 more source