Results 61 to 70 of about 2,079,368 (207)

Respiratory complex I‐mediated NAD+ regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21Cip1 expression by SIRT3 and SIRT7

Molecular Oncology, EarlyView.
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi, Kazunori Mori, Hidetsugu Nakagawa, Momoko Uchida, Fumihiro Ishikawa, Motoko Shibanuma   +5 more
wiley   +1 more source

Measuring the impact of spatial perturbations on the relationship between data privacy and validity of descriptive statistics. [PDF]

Int J Health Geogr, 2021
Broen K, Trangucci R, Zelner J.
europepmc   +1 more source

CARACTERIZING THE PUBLIC HEALTH SYSTEM REFORM USING THE STATISTICAL SURVEY APPROACH [PDF]

Assuring the health of the general public is a major objective of each country’s public health system. To insure this goal the public health system needs to offer good quality and prompt services according to the population’s needs The paper presents the
Andrei Tudorel, Calin Catalina, Stancu Stelian, Stancu Stelian, Tusa Erika   +4 more
core  

Survey on the Finnsh biotechnology industry: Background and descriptive statistics [PDF]

, 2005
ETLA, the Research Institute of the Finnish Economy, conducted surveys at the end of 2004 and at the beginning of 2002 on the enterprises listed in the Index of Biotechnology Companies in the Finnish Bioindustries organization.
Hermans, Raine, Kulvik, Martti, Tahvanainen, Antti-Jussi   +2 more
core  

Analysis of comprehensive genomic profiling of solid tumors with a novel assay for broad analysis in clinical diagnostics

Molecular Oncology, EarlyView.
In molecular cancer diagnostics, comprehensive genomic profiling (CGP) is going to replace the small NGS panels since it provides all clinically relevant somatic variants as well as genomic biomarkers with clinical value. Here, we compared two CGP assays and demonstrate that the choice for diagnostic implementation will depend on the specific ...
Guy Froyen, Pieter‐Jan Volders, Ellen Geerdens, Severine Berden, Joni Van der Meulen, Aaron De Cock, Stefanie Vermeire, Jacques Van Huysse, Marie de Barsy, Gabriela Beniuga, Wendy W. J. de Leng, Anne M. L. Jansen, Imke Demers, Zeliha Ozgur, Hendrikus Jan Dubbink, Ernst‐Jan M. Speel, Wilfred F. J. van IJcken, Brigitte Maes   +17 more
wiley   +1 more source

Dataset of service life data for 100 building elements and technical systems including their descriptive statistics and fitting to lognormal distribution. [PDF]

Data Brief, 2021
Goulouti K, Favre D, Giorgi M, Padey P, Galimshina A, Habert G, Lasvaux S.   +6 more
europepmc   +1 more source

Dyspnea Experience and Dyspnea Management in Patients with Chronic Obstructive Pulmonary Disease in Bangladesh [PDF]

, 2014
Purpose: This study aimed to evaluate dyspnea experience and dyspnea management intervention used by Chronic Obstructive Pulmonary Disease (COPD) patients in Bangladesh.Methods: A descriptive cross-sectional design was used.
Matchim, Y. (Yaowarat), Parveen, S. (Shahanaz), Thaniwattananon, P. (Ploenpit)   +2 more
core   +1 more source

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

Molecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane, Jérôme Ambroise, Cédric van Marcke, Mieke Van Bockstal, Martine Berlière, Christine Galant, Hélène Dano, Médina Lougué, Elena Benidovskaya, Guy Jerusalem, Vincent Bours, Claire Josse, Jérôme Thiry, Aurélie Daumerie, Caroline Bouzin, Cyril Corbet, François P. Duhoux   +16 more
wiley   +1 more source

Main Concepts for Two Picture Description Tasks: An Addition to Richardson and Dalton, 2016 [PDF]

, 2019
Background: Proposition analysis of the discourse of persons with aphasia (PWAs) has a long history, yielding important advancements in our understanding of communication impairments in this population.
Dalton, Sarah Grace, Richardson, Jessica D.   +1 more
core   +1 more source

Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer

Molecular Oncology, EarlyView.
We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas, Konstantinos Voutetakis, Vivian Kosmidou, Spyridon Tsikalakis, Spyridon Roditis, Konstantinos Pateas, Ryangguk Kim, Kymberleigh Pagel, Stephan Wolf, Gregor Warsow, Antonia Dimitrakopoulou‐Strauss, Georgios N. Zografos, Alexander Pintzas, Johannes Betge, Olga Papadodima, Stefan Wiemann   +15 more
wiley   +1 more source